Aniseed - Cis-regulation

Region 'REG00000235'

Cis-regulatory Region

Name

Rorb -616/-456

Short name

n/a

Region ID

REG00000235

Status

Curated

Origin

natural region from C. robusta formely Ciona int. type A

Type of Activity

regulatory_region
(enhancer)

Author

Pierre Khoueiry (2007-11-12)

Annotator

Pierre Khoueiry (2010-06-10)

Curator

Delphine Dauga (2010-06-10)

View position in WashU

Description

- Coordinates on the V1.0 ciona genome: scaffold_3:474993-475152 (s3:475043)

Hierarchy of Regulatory Regions

Modification of Ci-RORb -1649bp/4353bp by deletion

Ci-RORb -1649bp/4353bp REG00000445 [ regulatory_region (extended_promoter) ]

Regulated gene(s)

KH2012:KH.C8.737 (MUSK; ROR1; ROR2)

Construct(s) made to test this region

CONS00000227: Rorb -616/-456 pFOG::LacZ

Show in situ data

Overview of functional TF binding sites in this region

2,708,4622,708,621

	Motif Name	Binding Factor(s)	Sequence	Position in Region
1	Ets	n/a	TTCC	[-608 / -605]
2	ZnF_(GATA)	n/a	TATC	[-569 / -566]
3	ZnF_(GATA)	n/a	GATA	[-548 / -545]
4	Ets	n/a	TTCC	[-534 / -531]
5	Ets	n/a	TTCC	[-493 / -490]
6	Ets	n/a	GGAA	[-468 / -465]

Sequence

Aniseed Coordinates: [2,708,462 / 2,708,621] on scaffold KhC8

Show sequence

Length: 160

TGGTATAATTCCCAATTAGAACACACAGGTAGAAAAATACATTAGAATATCTTTGATTAG
ACTAGCAAGATAGGCACCTAATTTCCTATGTTAGTACAACTGGTTTTATAAAATTATAAA
AATTTCCTGCTATAATCGGTTAGAGCAAGGAACGGTGATT

Reference(s)

Khoueiry et al. (2010). A cis-regulatory signature in ascidians and flies, independent of transcription factor binding sites. Curr. Biol. 20(9):792-802