Description

This region, placed in front of the pfog basal promoter, drives expression in b-epidermis (particulary mid-line and lateral region), nerve cord
and a part of a-epidermis.

Coordinates are based on KH transcript model.

Hierarchy of Regulatory Regions

Modification of Ci-Nodal -2260/-1732 by deletion

Regulated gene(s)

KH2012:KH.L106.16 (BMP10; GDF2; NODAL)

Construct(s) made to test this region

CONS00001524: p.Ci-Nodal -2260/-2078>H2B::Venus

CONS00000295: Ci-Nodal -2260/-2078 pFOG::LacZ

Overview of functional TF binding sites in this region

33,01033,191

	Motif Name	Binding Factor(s)	Sequence	Position in Region	Comment

Sequence

Aniseed Coordinates: [33,010 / 33,191] on scaffold KhL106

Sequence from JGI V1.0

Reference(s)

Stolfi et al. (2015). Migratory neuronal progenitors arise from the neural plate borders in tunicates. Nature 527(7578):371-4

Khoueiry et al. (2010). A cis-regulatory signature in ascidians and flies, independent of transcription factor binding sites. Curr. Biol. 20(9):792-802