- Region 'REG00001324'
Cis-regulatory Region
Name
Cirobu.REG.KH2012.C9:35685-35739|Fkbp9
Short name
n/a
Region ID
REG00001324
Status
Curated
Origin
natural region from C. robusta formely Ciona int. type A
Type of Activity
no_output
Author
Diana S. José-Edwards (2018-05-08)
Annotator
Marion Gueroult-Bellone (2018-05-08)
Curator
Marion Gueroult-Bellone (2018-05-08)
This 55bp sequence, located in the upstream region of KH.C9.778, drives no reporter gene expression in notochord. It contains 1 Sp1/Klf, 3 E-box and 1 Brachyury putative binding sites. Compared to the active WT enhancer, it lacks 2 Brachyury binding site.
Modification of Cirobu.REG.KH2012.C9:35651-35739|Fkbp9 by deletion
- Cirobu.REG.KH2012.C9:35562-36707|Fkbp9 REG00001318 [ regulatory_region (complex_region) ]
35,68535,739
| Motif Name | Binding Factor(s) | Sequence | Position in Region | Comment | |
|---|---|---|---|---|---|
| 1 | T-Box | n/a | taacac | [35,688 / 35,694] | This is one of the 3 Brachyury binding sites located in the notochord enhancer of KH.C9.778. |
| 2 | bHLH | n/a | cacgtg | [35,691 / 35,697] | This is one of the 3 E-box binding sites located in the notochord enhancer of KH.C9.778. |
| 3 | bHLH | n/a | catttg | [35,704 / 35,710] | This is one of the 3 E-box binding sites located in the notochord enhancer of KH.C9.778. |
| 4 | bHLH | n/a | caattg | [35,725 / 35,731] | This is one of the 3 E-box binding sites located in the notochord enhancer of KH.C9.778. Its mutation does not affect ehnacer activity. |
| 5 | ZnF_(C2H2) | n/a | ggtgg | [35,730 / 35,735] | This Sp1/Klf binding site is located in the notochord enhancer of KH.C9.778. |
Aniseed Coordinates: [35,685 / 35,739] on scaffold KhC9
This sequence was retrieved using ANISEED Blast tool, thanks to the information provided in FigS1ab and TableS5 of Jose-Edwards et al. 2015.
Show sequence
Length: 55
aagtaacacgtgacttcaacatttgctcaatgctggaaagcaattggtggataag
