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CIS-REGULATION

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  1. Region 'REG00001359' > 
  2. Region 'REG00001335' > 
  3. Region 'REG00001312' > 
  4. Region 'REG00001330' > 
  5. Region 'REG00001328'

Cis-regulatory Region

Name

Cirobu.REG.KH2012.C10:2816957-2817555|Ubp4,Ubp8,Ubp11

Short name

n/a

Region ID

REG00001328

Status

Curated

Origin

natural region from C. robusta formely Ciona int. type A

Type of Activity

no_output

Author

Diana S. José-Edwards (2018-05-08)

Annotator

Marion Gueroult-Bellone (2018-05-08)

Curator

Marion Gueroult-Bellone (2018-05-08)

View position in WashU

Description

This 89bp sequence, located in the downstream region of KH.C10.320, drives no reporter gene expression in notochord. Compared to the larger active cis-regulatory region, it lacks a cluster of 2 E-box and 1 Brachyury putative binding sites.

Hierarchy of Regulatory Regions

Modification of Cirobu.REG.KH2012.C10:2816169-2817555|Ubp4,Ubp8,Ubp11 by deletion

Regulated gene(s)

KH2012:KH.C10.320 (USP11; USP32; USP4)

Construct(s) made to test this region

CONS00001348: p.Cirobu.REG.KH2012.C10:2816957-2817555>lacZ

Show in situ data
Overview of functional TF binding sites in this region

2,816,9572,817,555

Motif Name Binding Factor(s) Sequence Position in Region Comment

Sequence

Aniseed Coordinates: [2,816,957 / 2,817,555] on scaffold KhC10

This sequence was retrieved using ANISEED Blast tool, thanks to the information provided in FigS1.b and TableS5 of Jose-Edwards et al. 2015.

Show sequence

Length: 599

aatcttcaagttccttagcaaacaagcttaccagtaacggtgtttggtttgtcgcggctc
ttgtttaatatcgcataaatgttccaggaattgttactaaccgtacagtctcgatatcag
tgcaaattgtcacgcgaatattttcacgttaacccagttttgtgagttttttacttgaaa
attattttaaagtaggaacgcgggattatttggttgtctagaccagtgctcttcgacttt
taatgggttggtgaaccccttaagttgttgcgtcgaactcatgcacccctgattgcttta
acgtaaaactaatgaagtttcacaattcccagtgatgcaagatataaaattcatataaaa
aaatgtaggaaagtggctaaattggttaaaaaagtttaaaatgaaaaaatattgctgaaa
attgtcgaagtttgtgatgcacccttgtatacctttttgcactggtgcacccctggcata
ttttggtgcaccctagggtgcaccgtgcacaccggttgaagagcactggtctagactcta
gagtgtcctatataacccgcgaattcgttacttatattgtatttgataacgcggtattt

Reference(s)

José-Edwards et al. (2015). Brachyury, Foxa2 and the cis-Regulatory Origins of the Notochord. PLoS Genet. 11(12):e1005730

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