- Region 'REG00001355'
Cis-regulatory Region
Name
Cirobu.REG.KH2012.C12:712425-712628|CbpD,CbpE,CbpN
Short name
n/a
Region ID
REG00001355
Status
Curated
Origin
natural region from C. robusta formely Ciona int. type A
Type of Activity
regulatory_region
(enhancer)
Author
Diana S. José-Edwards (2018-05-09)
Annotator
Marion Gueroult-Bellone (2018-05-09)
Curator
Marion Gueroult-Bellone (2018-05-09)
This 213bp sequence, located in the downstream region of KH.C12.16, drives reporter gene expression in notochord. It contains a cluster of 3 Fox and 1 Myb#3 putative binding sites.
Modification of Cirobu.REG.KH2012.C12:712425-714190|CbpD,CbpE,CbpN by deletion
- Cirobu.REG.KH2012.C12:711845-714190|CbpD,CbpE,CbpN REG00001352 [ regulatory_region (complex_region) ]
712,425712,628
| Motif Name | Binding Factor(s) | Sequence | Position in Region | Comment | |
|---|---|---|---|---|---|
| 1 | Fox | n/a | acaaaca | [712,452 / 712,459] | This is one of the 3 Fox binding sites located in the notochord-active enhancer of KH.C12.16. |
| 2 | Fox | n/a | acaaata | [712,465 / 712,472] | This is one of the 3 Fox binding sites located in the notochord-active enhancer of KH.C12.16. |
| 3 | Fox | n/a | acaata | [712,480 / 712,486] | This is one of the 3 Fox binding sites located in the notochord-active enhancer of KH.C12.16. |
| 4 | Helix Turn Helix / Tryptophane clusters | n/a | ccgttg | [712,519 / 712,525] | This Myb#3 binding site is located in the notochord-active enhancer of KH.C12.16. Mutation or deletion of this binding site inhibits enhancer activity in the notochord. |
Aniseed Coordinates: [712,425 / 712,628] on scaffold KhC12
This sequence was retrieved using ANISEED Blast tool, thanks to the information provided in FigS1.e and TableS5 of Jose-Edwards et al. 2015.
Show sequence
Length: 204
tcacatatatgcgttgtgacgtcatatacaaacaacaagaacaaatagtgacgtaacaat
acaaatatcgagtaaattcgacgtcacggttgaaccgttgtgtggataagttaaccatga
cgtcaccggtataaaggtaatgcggtgacgtcacagataagatgaaagtcttcaacgcga
atataaaacttctggcatcaattt
