- Clone 'cien174142' >
- Transcript 'KH2012:KH.S215.4.v1....' >
- Transcript 'KH2012:KH.C12.670.v1...' >
- Transcript 'KH2012:KH.C9.176.v3....' >
- Region 'REG00001513'
Cis-regulatory Region
Name
Cirobu.REG.KhC5:2278468-2279057|tyrp1/2a
Short name
tyrp1/2a 0.6kb upstream TSS (Esposito 2012)
Region ID
REG00001513
Status
Curated
Origin
natural region from C. robusta formely Ciona int. type A
Type of Activity
regulatory_region
(extended_promoter)
Author
Rosaira Esposito (2020-11-12)
Annotator
Marion Gueroult-Bellone (2020-11-12)
Curator
Marion Gueroult-Bellone (2020-11-12)
The results indicated that pCi-tyrp1/2a-0.6 had similar activity to pCi-tyrp1/2a, thus permitting an initial dissection of the regulatory region directing Ci-tyrp1/2a transcription.
Modification of Cirobu.REG.KhC5:2277494-2279057|tyrp1/2a by deletion
2,278,4682,279,057
| Motif Name | Binding Factor(s) | Sequence | Position in Region | Comment |
|---|
Aniseed Coordinates: [2,278,468 / 2,279,057] on scaffold KhC5
The 600bp region lacated upstream of tyrp1/2a TSS contains a 400 bp highly conserved fragment through eumetazoans. This cis-regulatory module is able to recapitulate endogenous Ci-tyrp1a expression pattern in pigmented cells precursors.
Show sequence
Length: 590
CTAGAAGAGATAGAATGGGACTTTACAACAATGTTATTTCGTGACACTGTAGCGTTTAAA
TAAAGACCACGACTATAAAATAACGCCAACTTCATAAAAATATGCACAACATTCATTATG
GTTTTATTTAAACATAGCAATTCATTGTTTAAATTGCGCAATAAAGTTTGTAATCAGAAC
ATCCGAGATTACTAATACCAAGCAACTTTTTTATCAATACCGATCACACAACCCGCAGTT
ATTACATTGTCGTTTAAGAAGGAAATCCACTACAGAACAAACGAACAAATAAGTTGCTGG
ATTTGAGTAACTTGTGACTCCGGTTAGGCTTAGCTTTTTAATCCGTTTAATTCATCACTC
CCATGAAAAGTTTCATTATAAAAGCTGCGAAATCAGTTCGAACAGCAGAGCAGTGAAAGT
ACCTCCACCAGTAGCAACTAATACAGTAAGGAAGGCAAAATCGAGTGGGTATATGGAGCG
GCAACGTCTCTATTTCAAGCTCATCGGTTGGTTTGCATGTAGAGATAAACTACCCAAGTG
TAGTTACCTAGAATATCATTTACGACGACTACAATCGCTAACCACTTACT
