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- Construct 'CONS00000659'
Construct
ID
CONS00000659
Name
pCi-Pitx -2735/-2540 TALE-class sites mutated:CES2:LacZ
Min Promoter
Endogenous Promoter
Reporter
Comment
The two TALE-class Meis/TGIF regulatory motifs were mutated (TGACAA => AGACAA and TGACAG => TTACAG). The mutations (m3 in the paper) affect the expression in the neurohypophysis primordium, anterior epidermis, ventral anterior sensory vesicle, but in the mesenchyme it seems that expression is higher.
The sequence is based on the first codon on the KH transcript.
Show sequence
Length: 195
ACGGATTAAGGTAATATTTCTTTTTATGTTGCCGCCCAGTCGGTTCCAGACAATACACTT
ACAGGTAGTGCGAATAAAAGGCGCTCGTGGATGTAAAAAAACACTAATAATCTTCAGTAA
TTTCCGTGCCTTTCCTATGGGCGAAAACTCCCGCCGTGTGAAACGACTTCAAAAGGCGGA
CAGTCGCCGCCAAGG