Gene Card
Best human hits
DAB2IP; RASA1; RASAL2
Species
Unique Gene ID
Boleac.g00006828
Gene Model ID
Boleac.CG.SB_v3.S29.g06828
Location
S29:273989..284899
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
SH2 | Pfam | SH2 domain |
PH_domain | SMART | Pleckstrin homology domain |
RasGAP_SH3 | CDD | RasGAP, SH3 domain |
PH_domain | Pfam | Pleckstrin homology domain |
PH-like_dom_sf | Gene3D | PH-like domain superfamily |
SH2_dom_sf | SUPERFAMILY | SH2 domain superfamily |
RasGAP_dom | Pfam | Ras GTPase-activating domain |
RasGAP_CS | ProSitePatterns | Ras GTPase-activating protein, conserved site |
SH2 | SMART | SH2 domain |
PH_domain | ProSiteProfiles | Pleckstrin homology domain |
p120-RasGAP | PANTHER | Ras GTPase-activating protein 1 |
C2_domain_sf | Gene3D | C2 domain superfamily |
C2_dom | SMART | C2 domain |
C2_dom | Pfam | C2 domain |
SH3-like_dom_sf | SUPERFAMILY | SH3-like domain superfamily |
SH3_domain | ProSiteProfiles | SH3 domain |
SH2_dom_sf | Gene3D | SH2 domain superfamily |
SH2 | ProSiteProfiles | SH2 domain |
RasGAP_dom | SMART | Ras GTPase-activating domain |
SH2 | PRINTS | SH2 domain |
SH3_domain | Pfam | SH3 domain |
SH3_domain | SMART | SH3 domain |
RasGAP_dom | ProSiteProfiles | Ras GTPase-activating domain |
Rho_GTPase_activation_prot | SUPERFAMILY | Rho GTPase activation protein |
GO Term | Annotation Origin | Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
MAPK cascade | Hs | biological process |
mitotic cytokinesis | Hs | biological process |
vasculogenesis | Hs | biological process |
ruffle | Hs | cellular component |
phosphotyrosine residue binding | Hs | molecular function |
GTPase activity | Hs | molecular function |
GTPase activator activity | Hs | molecular function |
receptor binding | Hs | molecular function |
protein binding | Hs | molecular function |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
negative regulation of cell adhesion | Hs | biological process |
signal transduction | Hs | biological process |
regulation of cell shape | Hs | biological process |
potassium channel inhibitor activity | Hs | molecular function |
regulation of actin filament polymerization | Hs | biological process |
intrinsic component of the cytoplasmic side of the plasma membrane | Hs | cellular component |
intracellular signal transduction | Hs | biological process |
negative regulation of apoptotic process | Hs | biological process |
regulation of GTPase activity | Hs | biological process |
negative regulation of neuron apoptotic process | Hs | biological process |
positive regulation of GTPase activity | Hs | biological process |
negative regulation of Ras protein signal transduction | Hs | biological process |
ephrin receptor signaling pathway | Hs | biological process |
blood vessel morphogenesis | Hs | biological process |
GTPase binding | Hs | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
ruffle | Hs | cellular component | 827 | 0.0 |
phosphotyrosine residue binding | Hs | molecular function | 827 | 0.0 |
GTPase activity | Hs | molecular function | 827 | 0.0 |
GTPase activator activity | Hs | molecular function | 827 | 0.0 |
receptor binding | Hs | molecular function | 827 | 0.0 |
death receptor binding | Hs | molecular function | 190 | 1.77e-49 |
protein binding | Hs | molecular function | 827 | 0.0 |
cytoplasm | Hs | cellular component | 827 | 0.0 |
cytosol | Hs | cellular component | 827 | 0.0 |
plasma membrane | Hs | cellular component | 827 | 0.0 |
membrane | Hs | cellular component | 190 | 1.77e-49 |
SH3 domain binding | Hs | molecular function | 190 | 1.77e-49 |
potassium channel inhibitor activity | Hs | molecular function | 827 | 0.0 |
kinase binding | Hs | molecular function | 190 | 1.77e-49 |
protein kinase binding | Hs | molecular function | 190 | 1.77e-49 |
endocytic vesicle | Hs | cellular component | 190 | 1.77e-49 |
axon | Hs | cellular component | 190 | 1.77e-49 |
dendrite | Hs | cellular component | 190 | 1.77e-49 |
intrinsic component of the cytoplasmic side of the plasma membrane | Hs | cellular component | 827 | 0.0 |
mitogen-activated protein kinase kinase binding | Hs | molecular function | 190 | 1.77e-49 |
mitogen-activated protein kinase kinase kinase binding | Hs | molecular function | 190 | 1.77e-49 |
phosphatidylinositol-3-phosphate binding | Hs | molecular function | 190 | 1.77e-49 |
neuronal cell body membrane | Hs | cellular component | 190 | 1.77e-49 |
signaling adaptor activity | Hs | molecular function | 190 | 1.77e-49 |
phosphatidylinositol 3-kinase regulatory subunit binding | Hs | molecular function | 190 | 1.77e-49 |
identical protein binding | Hs | molecular function | 190 | 1.77e-49 |
protein homodimerization activity | Hs | molecular function | 190 | 1.77e-49 |
cell projection | Hs | cellular component | 190 | 1.77e-49 |
neuronal cell body | Hs | cellular component | 190 | 1.77e-49 |
vascular endothelial growth factor receptor 2 binding | Hs | molecular function | 190 | 1.77e-49 |
phosphatidylinositol 3-kinase binding | Hs | molecular function | 190 | 1.77e-49 |
cerebellar mossy fiber | Hs | cellular component | 190 | 1.77e-49 |
climbing fiber | Hs | cellular component | 190 | 1.77e-49 |
macromolecular complex binding | Hs | molecular function | 190 | 1.77e-49 |
cadherin binding | Hs | molecular function | 190 | 1.77e-49 |
GTPase binding | Hs | molecular function | 827 | 0.0 |
protein phosphatase 2A binding | Hs | molecular function | 190 | 1.77e-49 |
extracellular exosome | Hs | cellular component | 190 | 1.77e-49 |
phosphatidylinositol-4-phosphate binding | Hs | molecular function | 190 | 1.77e-49 |
14-3-3 protein binding | Hs | molecular function | 190 | 1.77e-49 |
parallel fiber | Hs | cellular component | 190 | 1.77e-49 |
AIP1-IRE1 complex | Hs | cellular component | 190 | 1.77e-49 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
GTPase activator activity | PANTHER | molecular function | 0.0 |
protein binding | SUPERFAMILY | molecular function | 1.87E-8 |
signal transduction | SUPERFAMILY | biological process | 5.89E-72 |
regulation of GTPase activity | SMART | biological process | 1.1E-91 |
positive regulation of GTPase activity | PANTHER | biological process | 0.0 |
negative regulation of Ras protein signal transduction | PANTHER | biological process | 0.0 |