Gene Card
Best human hits
HDAC1; HDAC2; HDAC3
Species
Unique Gene ID
Boschl.g00013654
Gene Model ID
Boschl.CG.Botznik2013.chr5.g13654
Location
chr5:25421637..25428819
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
7 results
| IPR Term | Analysis | Definition |
|---|---|---|
| His_deacetylse | PANTHER | Histone deacetylase superfamily |
| His_deacetylse_dom | Pfam | Histone deacetylase domain |
| His_deacetylse_dom_sf | Gene3D | Histone deacetylase domain superfamily |
| His_deacetylse | PRINTS | Histone deacetylase superfamily |
| His_deacetylse_1 | PIRSF | Histone deacetylase |
| His_deacetylse_1 | PRINTS | Histone deacetylase |
| Ureohydrolase_dom_sf | SUPERFAMILY | Ureohydrolase domain superfamily |
| GO Term | Annotation Origin | Type |
|---|
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
50 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| histone deacetylase complex | Hs | cellular component | 594 | 0.0 |
| chromatin | Hs | cellular component | 619 | 0.0 |
| nuclear chromatin | Hs | cellular component | 619 | 0.0 |
| transcription regulatory region sequence-specific DNA binding | Hs | molecular function | 594 | 0.0 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | Hs | molecular function | 619 | 0.0 |
| RNA polymerase II distal enhancer sequence-specific DNA binding | Hs | molecular function | 619 | 0.0 |
| core promoter sequence-specific DNA binding | Hs | molecular function | 594 | 0.0 |
| core promoter binding | Hs | molecular function | 594 | 0.0 |
| RNA polymerase II transcription factor binding | Hs | molecular function | 594 | 0.0 |
| RNA polymerase II repressing transcription factor binding | Hs | molecular function | 619 | 0.0 |
| RNA polymerase II transcription corepressor activity | Hs | molecular function | 594 | 0.0 |
| p53 binding | Hs | molecular function | 594 | 0.0 |
| chromatin binding | Hs | molecular function | 619 | 0.0 |
| transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 594 | 0.0 |
| transcription corepressor activity | Hs | molecular function | 431 | 3.13e-149 |
| RNA binding | Hs | molecular function | 619 | 0.0 |
| histone deacetylase activity | Hs | molecular function | 619 | 0.0 |
| protein binding | Hs | molecular function | 619 | 0.0 |
| nucleus | Hs | cellular component | 619 | 0.0 |
| nucleoplasm | Hs | cellular component | 619 | 0.0 |
| cytoplasm | Hs | cellular component | 619 | 0.0 |
| Golgi apparatus | Hs | cellular component | 431 | 3.13e-149 |
| cytosol | Hs | cellular component | 594 | 0.0 |
| spindle microtubule | Hs | cellular component | 431 | 3.13e-149 |
| plasma membrane | Hs | cellular component | 431 | 3.13e-149 |
| transcription factor binding | Hs | molecular function | 619 | 0.0 |
| membrane | Hs | cellular component | 619 | 0.0 |
| integral component of membrane | Hs | cellular component | 619 | 0.0 |
| Sin3 complex | Hs | cellular component | 619 | 0.0 |
| NuRD complex | Hs | cellular component | 619 | 0.0 |
| hydrolase activity | Hs | molecular function | 619 | 0.0 |
| transcriptional repressor complex | Hs | cellular component | 431 | 3.13e-149 |
| deacetylase activity | Hs | molecular function | 619 | 0.0 |
| enzyme binding | Hs | molecular function | 619 | 0.0 |
| cyclin binding | Hs | molecular function | 431 | 3.13e-149 |
| heat shock protein binding | Hs | molecular function | 619 | 0.0 |
| nucleosomal DNA binding | Hs | molecular function | 619 | 0.0 |
| NAD-dependent histone deacetylase activity (H3-K14 specific) | Hs | molecular function | 619 | 0.0 |
| macromolecular complex | Hs | cellular component | 619 | 0.0 |
| protein deacetylase activity | Hs | molecular function | 619 | 0.0 |
| activating transcription factor binding | Hs | molecular function | 594 | 0.0 |
| ESC/E(Z) complex | Hs | cellular component | 619 | 0.0 |
| histone deacetylase binding | Hs | molecular function | 619 | 0.0 |
| sequence-specific DNA binding | Hs | molecular function | 619 | 0.0 |
| transcription regulatory region DNA binding | Hs | molecular function | 594 | 0.0 |
| metal ion binding | Hs | molecular function | 594 | 0.0 |
| protein N-terminus binding | Hs | molecular function | 594 | 0.0 |
| NF-kappaB binding | Hs | molecular function | 619 | 0.0 |
| repressing transcription factor binding | Hs | molecular function | 594 | 0.0 |
| promoter-specific chromatin binding | Hs | molecular function | 619 | 0.0 |
GO (InterProScan)
2 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| histone deacetylase activity | PIRSF | molecular function | 4.1E-165 |
| histone deacetylation | PIRSF | biological process | 4.1E-165 |
