Gene Card
Best human hits
IRAK1; IRAK3; IRAK4
Unique Gene ID
Cirobu.g00000068
Gene Model ID
KH2012:KH.C1.1059
Location
KhC1:5382359..5387096
Transcript Models and Sequences
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000007925 |
NCBI Reference Sequence | XM_002128846.4 |
cien54049
Plate: VES78_H16
cima867383
Plate: VES66_C03
cieg055d24
Plate: R1CiGC24i14
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Prot_kinase_dom | SMART | Protein kinase domain |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
Prot_kinase_dom | Pfam | Protein kinase domain |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
magnesium ion binding | Blast | molecular function |
protein kinase activity | Orthology | molecular function |
protein serine/threonine kinase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
extracellular space | Blast | cellular component |
intracellular | Blast | cellular component |
nucleus | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
protein phosphorylation | Orthology | biological process |
signal transduction | Orthology | biological process |
membrane | Blast | cellular component |
kinase activity | Blast | molecular function |
transferase activity | Blast | molecular function |
cytokine-mediated signaling pathway | Orthology | biological process |
response to lipopolysaccharide | Orthology | biological process |
protein homodimerization activity | Orthology | molecular function |
innate immune response | Orthology | biological process |
protein heterodimerization activity | Orthology | molecular function |
intracellular signal transduction | Orthology | biological process |
positive regulation of catalytic activity | Orthology | biological process |
positive regulation of signal transduction | Orthology | biological process |
cellular response to stress | Orthology | biological process |
intracellular organelle part | Orthology | cellular component |
whole membrane | Orthology | cellular component |
endosome | Orthology | cellular component |
bounding membrane of organelle | Orthology | cellular component |
cell surface receptor signaling pathway | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
regulation of molecular function | Orthology | biological process |
transcription factor activity, sequence-specific DNA binding | Orthology | molecular function |
defense response | Orthology | biological process |
enzyme regulator activity | Blast | molecular function |
receptor binding | Blast | molecular function |
intracellular non-membrane-bounded organelle | Blast | cellular component |
integral component of plasma membrane | Blast | cellular component |
macromolecular complex | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 196 | 2.01e-53 |
magnesium ion binding | Hs | molecular function | 176 | 3.66e-47 |
protein kinase activity | Hs | molecular function | 196 | 2.01e-53 |
protein serine/threonine kinase activity | Hs | molecular function | 196 | 2.01e-53 |
NF-kappaB-inducing kinase activity | Hs | molecular function | 196 | 2.01e-53 |
interleukin-1 receptor binding | Hs | molecular function | 173 | 6.72e-47 |
protein binding | Hs | molecular function | 196 | 2.01e-53 |
ATP binding | Hs | molecular function | 196 | 2.01e-53 |
extracellular space | Hs | cellular component | 173 | 6.72e-47 |
intracellular | Hs | cellular component | 173 | 6.72e-47 |
nucleus | Hs | cellular component | 196 | 2.01e-53 |
cytoplasm | Hs | cellular component | 196 | 2.01e-53 |
lipid droplet | Hs | cellular component | 196 | 2.01e-53 |
cytosol | Hs | cellular component | 196 | 2.01e-53 |
plasma membrane | Hs | cellular component | 196 | 2.01e-53 |
endosome membrane | Hs | cellular component | 196 | 2.01e-53 |
membrane | Hs | cellular component | 196 | 2.01e-53 |
kinase activity | Hs | molecular function | 196 | 2.01e-53 |
transferase activity | Hs | molecular function | 196 | 2.01e-53 |
heat shock protein binding | Hs | molecular function | 196 | 2.01e-53 |
protein homodimerization activity | Hs | molecular function | 196 | 2.01e-53 |
interleukin-1 receptor complex | Hs | cellular component | 196 | 2.01e-53 |
protein heterodimerization activity | Hs | molecular function | 196 | 2.01e-53 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 1.3E-43 |
ATP binding | Pfam | molecular function | 1.3E-43 |
protein phosphorylation | Pfam | biological process | 1.3E-43 |