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GENE CARD

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Gene Card

Best human hits

DUSP1; DUSP2; DUSP4

Unique Gene ID

Cirobu.g00000090

Gene Model ID

KH2012:KH.C1.1079

Location

KhC1:6298693..6302536

External Database Gene Card

External database links

2 results

Collections

Gateway full ORF

2 results

cima873673

Plate: VES67_F05

cima884158

Plate: VES69_A13

Gene collection 1 (N. Satoh)

1 result

cicl053i15

Plate: R1CiGC14c24

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

17 results

IPR Term Analysis Definition
Tyr_Pase_cat SMART Protein-tyrosine phosphatase, catalytic
TYR_PHOSPHATASE_DUAL_dom CDD Dual specificity protein phosphatase domain
Rhodanese-like_dom_sf SUPERFAMILY Rhodanese-like domain superfamily
TYR_PHOSPHATASE_DUAL_dom SMART Dual specificity protein phosphatase domain
Rhodanese-like_dom SMART Rhodanese-like domain
Prot-tyrosine_phosphatase-like Gene3D Protein-tyrosine phosphatase-like
Dual-sp_phosphatase_cat-dom Pfam Dual specificity phosphatase, catalytic domain
Rhodanese-like_dom Pfam Rhodanese-like domain
Prot-tyrosine_phosphatase-like SUPERFAMILY Protein-tyrosine phosphatase-like
Tyr_Pase_AS ProSitePatterns Protein-tyrosine phosphatase, active site
Rhodanese-like_dom ProSiteProfiles Rhodanese-like domain
TYR_PHOSPHATASE_DUAL_dom ProSiteProfiles Dual specificity protein phosphatase domain
Rhodanese-like_dom_sf Gene3D Rhodanese-like domain superfamily
MKP PRINTS Mitogen-activated protein (MAP) kinase phosphatase
DUSP PANTHER Dual specificity phosphatase
TYR_PHOSPHATASE_dom ProSiteProfiles Tyrosine specific protein phosphatases domain
Atypical_DUSP PRINTS Atypical dual specificity phosphatase

GOSlim

28 results

GO Term Annotation Origin Type
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
protein dephosphorylation Orthology biological process
response to oxidative stress Orthology biological process
cell cycle Orthology biological process
response to organic substance Orthology biological process
dephosphorylation Orthology biological process
hydrolase activity Orthology molecular function
nuclear membrane Orthology cellular component
intracellular signal transduction Orthology biological process
regulation of apoptotic process Orthology biological process
positive regulation of apoptotic process Orthology biological process
negative regulation of apoptotic process Orthology biological process
regulation of catalytic activity Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
negative regulation of signal transduction Orthology biological process
anatomical structure formation involved in morphogenesis Orthology biological process
multicellular organism development Orthology biological process
response to lipid Orthology biological process
cellular response to organic substance Orthology biological process
protein phosphorylation Orthology biological process
protein kinase binding Orthology molecular function
reproductive process Orthology biological process
mitotic cell cycle phase transition Orthology biological process
positive regulation of catalytic activity Orthology biological process
positive regulation of signal transduction Orthology biological process

GO (Orthology)

45 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
inactivation of MAPK activity Hs biological process
endoderm formation Hs biological process
phosphoprotein phosphatase activity Hs molecular function
protein tyrosine phosphatase activity Hs molecular function
non-membrane spanning protein tyrosine phosphatase activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
protein dephosphorylation Hs biological process
response to oxidative stress Hs biological process
cell cycle Hs biological process
protein tyrosine/serine/threonine phosphatase activity Hs molecular function
protein tyrosine/threonine phosphatase activity Hs molecular function
response to light stimulus Hs biological process
response to organic substance Hs biological process
dephosphorylation Hs biological process
hydrolase activity Hs molecular function
phosphatase activity Hs molecular function
MAP kinase tyrosine/serine/threonine phosphatase activity Hs molecular function
growth factor binding Hs molecular function
nuclear membrane Hs cellular component
response to estradiol Hs biological process
response to retinoic acid Hs biological process
cellular response to hormone stimulus Hs biological process
peptidyl-tyrosine dephosphorylation Hs biological process
intracellular signal transduction Hs biological process
peptidyl-threonine dephosphorylation Hs biological process
response to hydrogen peroxide Hs biological process
regulation of apoptotic process Hs biological process
positive regulation of apoptotic process Hs biological process
negative regulation of apoptotic process Hs biological process
negative regulation of MAP kinase activity Hs biological process
negative regulation of MAPK cascade Hs biological process
mitogen-activated protein kinase binding Hs molecular function
response to glucocorticoid Hs biological process
negative regulation of meiotic cell cycle Hs biological process
response to cAMP Hs biological process
response to calcium ion Hs biological process
negative regulation of ERK1 and ERK2 cascade Hs biological process
mitotic cell cycle arrest Hs biological process
regulation of mitotic cell cycle spindle assembly checkpoint Hs biological process
MAP kinase serine/threonine phosphatase activity Hs molecular function
MAPK cascade Hs biological process
activation of MAPK activity Hs biological process

GO (Blast)

16 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
phosphoprotein phosphatase activity Hs molecular function 278 1.93e-90
protein tyrosine phosphatase activity Hs molecular function 278 1.93e-90
non-membrane spanning protein tyrosine phosphatase activity Hs molecular function 278 1.93e-90
protein binding Hs molecular function 278 1.93e-90
nucleus Hs cellular component 278 1.93e-90
nucleoplasm Hs cellular component 257 5.74e-82
cytoplasm Hs cellular component 278 1.93e-90
protein tyrosine/serine/threonine phosphatase activity Hs molecular function 278 1.93e-90
protein tyrosine/threonine phosphatase activity Hs molecular function 278 1.93e-90
hydrolase activity Hs molecular function 278 1.93e-90
phosphatase activity Hs molecular function 278 1.93e-90
MAP kinase tyrosine/serine/threonine phosphatase activity Hs molecular function 278 1.93e-90
growth factor binding Hs molecular function 278 1.93e-90
nuclear membrane Hs cellular component 235 1.90e-74
mitogen-activated protein kinase binding Hs molecular function 235 1.90e-74
MAP kinase serine/threonine phosphatase activity Hs molecular function 257 5.74e-82

GO (InterProScan)

6 results

GO Term Analysis Type e-value
protein tyrosine phosphatase activity ProSitePatterns molecular function
protein dephosphorylation CDD biological process 2.98644E-60
protein tyrosine/serine/threonine phosphatase activity CDD molecular function 2.98644E-60
dephosphorylation Pfam biological process 1.9E-41
phosphatase activity ProSiteProfiles molecular function 14.6
MAP kinase tyrosine/serine/threonine phosphatase activity PRINTS molecular function 1.4E-17