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GENE CARD

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Gene Card

Best human hits

EPHA4; EPHA7; EPHB2

Unique Gene ID

Cirobu.g00000095

Gene Model ID

KH2012:KH.C1.1083

Location

KhC1:1000017..1031066

Transcript Models and Sequences

  KH2012:KH.C1.1083.v1.A.SL1-1

External Database Gene Card
Collections

Gateway full ORF

1 result

cima898666

Plate: VES72_I09

Gene collection 1 (N. Satoh)

1 result

cilv003g03

Plate: R1CiGC25i05

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

25 results

IPR Term Analysis Definition
Tyr_kinase_AS ProSitePatterns Tyrosine-protein kinase, active site
FN3_dom SMART Fibronectin type III
Ephrin_rcpt_lig-bd_dom SMART Ephrin receptor ligand binding domain
Ig-like_fold Gene3D Immunoglobulin-like fold
Eph_TM Pfam Ephrin receptor, transmembrane domain
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
SAM SMART Sterile alpha motif domain
Galactose-bd-like_sf SUPERFAMILY Galactose-binding-like domain superfamily
Tyr_kinase_ephrin_rcpt PIRSF Ephrin receptor type-A /type-B
FN3_dom ProSiteProfiles Fibronectin type III
FN3_dom CDD Fibronectin type III
Galactose-bd-like_sf Gene3D Galactose-binding-like domain superfamily
FN3_dom Pfam Fibronectin type III
Ser-Thr/Tyr_kinase_cat_dom PRINTS Serine-threonine/tyrosine-protein kinase, catalytic domain
SAM Pfam Sterile alpha motif domain
SAM ProSiteProfiles Sterile alpha motif domain
Tyr-kin_ephrin_A/B_rcpt-like SMART Tyrosine-protein kinase ephrin type A/B receptor-like
Ser-Thr/Tyr_kinase_cat_dom Pfam Serine-threonine/tyrosine-protein kinase, catalytic domain
Ephrin_rcpt_lig-bd_dom ProSiteProfiles Ephrin receptor ligand binding domain
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site
Ephrin_rcpt_lig-bd_dom Pfam Ephrin receptor ligand binding domain
Tyr_kinase_cat_dom SMART Tyrosine-protein kinase, catalytic domain
SAM/pointed_sf SUPERFAMILY Sterile alpha motif/pointed domain superfamily
FN3_sf SUPERFAMILY Fibronectin type III superfamily

GOSlim

50 results

GO Term Annotation Origin Type
nucleotide binding Blast molecular function
protein kinase activity Blast molecular function
receptor binding Blast molecular function
protein binding Blast molecular function
ATP binding Blast molecular function
extracellular region Blast cellular component
nucleus Blast cellular component
cytoplasm Blast cellular component
endosome Blast cellular component
early endosome Blast cellular component
endoplasmic reticulum Blast cellular component
Golgi apparatus Blast cellular component
cytosol Blast cellular component
plasma membrane Blast cellular component
integral component of plasma membrane Blast cellular component
protein phosphorylation InterProScan biological process
axon guidance Blast biological process
cell surface Blast cellular component
membrane Blast cellular component
integral component of membrane Blast cellular component
kinase activity Blast molecular function
transferase activity Blast molecular function
cell junction Blast cellular component
axon Blast cellular component
identical protein binding Blast molecular function
cell projection Blast cellular component
neuronal cell body Blast cellular component
cell body Blast cellular component
macromolecular complex binding Blast molecular function
synapse Blast cellular component
postsynaptic membrane Blast cellular component
postsynapse Blast cellular component
binding Blast molecular function
transmembrane signaling receptor activity Blast molecular function
cell surface receptor signaling pathway Blast biological process
whole membrane Blast cellular component
mitochondrial membrane Blast cellular component
bounding membrane of organelle Blast cellular component
organelle Blast cellular component
neuron part Blast cellular component
plasma membrane region Blast cellular component
cytoskeletal part Blast cellular component
intracellular organelle part Blast cellular component
cell projection part Blast cellular component
synapse part Blast cellular component
molecular function regulator Blast molecular function
regulation of signal transduction Blast biological process
chemotaxis Blast biological process
signaling receptor activity Blast molecular function
protein kinase binding Blast molecular function

GO (Orthology)

No result

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type

GO (Blast)

54 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 910 0.0
amyloid-beta binding Hs molecular function 899 0.0
protein kinase activity Hs molecular function 910 0.0
protein tyrosine kinase activity Hs molecular function 910 0.0
transmembrane receptor protein tyrosine kinase activity Hs molecular function 910 0.0
receptor activity Hs molecular function 899 0.0
ephrin receptor activity Hs molecular function 910 0.0
GPI-linked ephrin receptor activity Hs molecular function 910 0.0
transmembrane-ephrin receptor activity Hs molecular function 910 0.0
receptor binding Hs molecular function 899 0.0
protein binding Hs molecular function 910 0.0
ATP binding Hs molecular function 910 0.0
extracellular region Hs cellular component 899 0.0
nucleus Hs cellular component 899 0.0
cytoplasm Hs cellular component 910 0.0
mitochondrial outer membrane Hs cellular component 910 0.0
endosome Hs cellular component 910 0.0
early endosome Hs cellular component 910 0.0
endoplasmic reticulum Hs cellular component 910 0.0
Golgi apparatus Hs cellular component 910 0.0
cytosol Hs cellular component 899 0.0
plasma membrane Hs cellular component 910 0.0
integral component of plasma membrane Hs cellular component 910 0.0
axon guidance receptor activity Hs molecular function 901 0.0
cell surface Hs cellular component 910 0.0
postsynaptic density Hs cellular component 910 0.0
membrane Hs cellular component 910 0.0
integral component of membrane Hs cellular component 910 0.0
kinase activity Hs molecular function 910 0.0
transferase activity Hs molecular function 910 0.0
cell junction Hs cellular component 910 0.0
filopodium Hs cellular component 910 0.0
axon Hs cellular component 910 0.0
dendrite Hs cellular component 910 0.0
neuromuscular junction Hs cellular component 910 0.0
early endosome membrane Hs cellular component 910 0.0
PH domain binding Hs molecular function 910 0.0
identical protein binding Hs molecular function 910 0.0
cell projection Hs cellular component 910 0.0
neuronal cell body Hs cellular component 901 0.0
dendritic spine Hs cellular component 910 0.0
dendritic shaft Hs cellular component 910 0.0
perikaryon Hs cellular component 910 0.0
axon terminus Hs cellular component 910 0.0
axonal growth cone Hs cellular component 910 0.0
cell body Hs cellular component 910 0.0
macromolecular complex binding Hs molecular function 899 0.0
synapse Hs cellular component 910 0.0
postsynaptic membrane Hs cellular component 910 0.0
chemorepellent activity Hs molecular function 901 0.0
ephrin receptor binding Hs molecular function 910 0.0
DH domain binding Hs molecular function 910 0.0
postsynapse Hs cellular component 899 0.0
protein tyrosine kinase binding Hs molecular function 910 0.0

GO (InterProScan)

8 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 7.9E-95
protein tyrosine kinase activity SMART molecular function 1.7E-131
ephrin receptor activity PIRSF molecular function 0.0
protein binding SMART molecular function 8.2E-83
ATP binding PIRSF molecular function 0.0
integral component of plasma membrane PIRSF cellular component 0.0
protein phosphorylation PIRSF biological process 0.0
transmembrane receptor protein tyrosine kinase signaling pathway PIRSF biological process 0.0