Gene Card
Best human hits
RHOA; RHOB; RHOF
Unique Gene ID
Cirobu.g00000321
Gene Model ID
KH2012:KH.C1.129
Location
KhC1:7845995..7848803
Transcript Models and Sequences
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000007565 |
NCBI Reference Sequence | NM_001032772.1 |
cien163900
Plate: VES95_M15
cien228448
Plate: VES105_L11
cilv039m12
Plate: R1CiGC28c18
- Ci-RhoD -3406/1048 REG00000650 [ regulatory_region (extended_promoter) ]
- Ci-RhoD -3406/601 REG00000651 [ regulatory_region (extended_promoter) ]
- Ci-RhoD -2606/1049 REG00000655 [ regulatory_region (extended_promoter) ]
- Ci-RhoD -1299/1049 REG00000656 [ regulatory_region (extended_promoter) ]
- Ci-RhoD -1005/1048 REG00000657 [ regulatory_region (extended_promoter) ]
- Ci-RhoD -645/1049 REG00000658 [ regulatory_region (extended_promoter) ]
- Ci-RhoD -441/1049 REG00000659 [ regulatory_region (extended_promoter) ]
- Ci-RhoD 228/989 REG00000660 [ regulatory_region (enhancer) ]
- Ci-RhoD 448/990 REG00000664 [ regulatory_region (enhancer) ]
- Ci-RhoD 565/989 REG00000661 [ regulatory_region (enhancer) ]
- Ci-RhoD 647/989 REG00000662 [ inactive_region ]
- Ci-RhoD 565/989 FoxF1 mutated REG00000669 [ regulatory_region (enhancer) ]
- Ci-RhoD 565/989 FoxF2 mutated REG00000670 [ regulatory_region (enhancer) ]
- Ci-RhoD 565/989 FoxF3 mutated REG00000671 [ regulatory_region (enhancer) ]
- Ci-RhoD 565/989 FoxF4 mutated REG00000672 [ regulatory_region (enhancer) ]
- Ci-RhoD 565/989 FoxF2/3 mutated REG00000673 [ regulatory_region (enhancer) ]
- Ci-RhoD 565/989 FoxF2/4 mutated REG00000674 [ regulatory_region (enhancer) ]
- Ci-RhoD 565/989 FoxF3/4 mutated REG00000675 [ regulatory_region (enhancer) ]
- Ci-RhoD 565/989 FoxF2/3/4 mutated REG00000676 [ regulatory_region (enhancer) ]
- Ci-RhoD 565/989 Ets1/2-1 mutated REG00000677 [ regulatory_region (enhancer) ]
- Ci-RhoD 565/989 Ets1/2-2 mutated REG00000678 [ regulatory_region (enhancer) ]
- Ci-RhoD 565/989 Ets1/2-1-2 mutated REG00000679 [ regulatory_region (enhancer) ]
- Ci-RhoD 448/835 REG00000665 [ regulatory_region (enhancer) ]
- Ci-RhoD 565/989 REG00000661 [ regulatory_region (enhancer) ]
- Ci-RhoD 228/835 REG00000666 [ inactive_region ]
- Ci-RhoD 448/990 REG00000664 [ regulatory_region (enhancer) ]
- Ci-RhoD 228/989 REG00000660 [ regulatory_region (enhancer) ]
- Ci-RhoD -441/1049 REG00000659 [ regulatory_region (extended_promoter) ]
- Ci-RhoD -645/1049 REG00000658 [ regulatory_region (extended_promoter) ]
- Ci-RhoD -1005/1048 REG00000657 [ regulatory_region (extended_promoter) ]
- Ci-RhoD -1299/1049 REG00000656 [ regulatory_region (extended_promoter) ]
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IPR Term | Analysis | Definition |
---|---|---|
Small_GTP-bd_dom | TIGRFAM | Small GTP-binding protein domain |
Small_GTPase | Pfam | Small GTPase superfamily |
P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
Small_GTPase_Rho | ProSiteProfiles | Small GTPase superfamily, Rho type |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
GTPase activity | Orthology | molecular function |
protein binding | Blast | molecular function |
GTP binding | Orthology | molecular function |
intracellular | Orthology | cellular component |
nucleus | Blast | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Blast | cellular component |
endosome | Orthology | cellular component |
early endosome | Orthology | cellular component |
endoplasmic reticulum membrane | Blast | cellular component |
cytosol | Orthology | cellular component |
cytoskeleton | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
focal adhesion | Blast | cellular component |
cell adhesion | Orthology | biological process |
small GTPase mediated signal transduction | Orthology | biological process |
membrane | Orthology | cellular component |
cell migration | Orthology | biological process |
lamellipodium | Blast | cellular component |
cell junction | Blast | cellular component |
axon | Blast | cellular component |
midbody | Blast | cellular component |
vesicle | Blast | cellular component |
cell projection | Blast | cellular component |
extracellular exosome | Orthology | cellular component |
cell periphery | Blast | cellular component |
protein targeting | Orthology | biological process |
protein kinase binding | Orthology | molecular function |
organelle organization | Orthology | biological process |
intracellular organelle part | Orthology | cellular component |
whole membrane | Orthology | cellular component |
bounding membrane of organelle | Orthology | cellular component |
cytoplasmic vesicle | Orthology | cellular component |
endomembrane system | Orthology | cellular component |
regulation of signal transduction | Orthology | biological process |
cell projection assembly | Orthology | biological process |
cytoplasmic part | Blast | cellular component |
cytoskeletal protein binding | Blast | molecular function |
anion binding | Blast | molecular function |
guanyl ribonucleotide binding | Blast | molecular function |
purine ribonucleoside binding | Blast | molecular function |
intracellular part | Blast | cellular component |
plasma membrane part | Blast | cellular component |
plasma membrane region | Blast | cellular component |
cell projection membrane | Blast | cellular component |
cell leading edge | Blast | cellular component |
postsynapse | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
GTPase activity | Hs | molecular function |
GTP binding | Hs | molecular function |
intracellular | Hs | cellular component |
cytoplasm | Hs | cellular component |
endosome | Hs | cellular component |
early endosome | Hs | cellular component |
cytosol | Hs | cellular component |
cytoskeleton | Hs | cellular component |
plasma membrane | Hs | cellular component |
actin filament organization | Hs | biological process |
small GTPase mediated signal transduction | Hs | biological process |
Rho protein signal transduction | Hs | biological process |
endosome membrane | Hs | cellular component |
membrane | Hs | cellular component |
positive regulation of cell migration | Hs | biological process |
secretory granule membrane | Hs | cellular component |
positive regulation of cell adhesion | Hs | biological process |
regulation of small GTPase mediated signal transduction | Hs | biological process |
extracellular exosome | Hs | cellular component |
protein targeting | Hs | biological process |
protein kinase binding | Hs | molecular function |
lamellipodium assembly | Hs | biological process |
focal adhesion assembly | Hs | biological process |
actin filament bundle assembly | Hs | biological process |
regulation of actin cytoskeleton reorganization | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 173 | 2.43e-54 |
GTPase activity | Hs | molecular function | 173 | 2.43e-54 |
protein binding | Hs | molecular function | 173 | 2.43e-54 |
GTP binding | Hs | molecular function | 173 | 2.43e-54 |
intracellular | Hs | cellular component | 173 | 2.43e-54 |
nucleus | Hs | cellular component | 173 | 2.43e-54 |
cytoplasm | Hs | cellular component | 172 | 6.07e-54 |
mitochondrion | Hs | cellular component | 172 | 6.07e-54 |
endosome | Hs | cellular component | 173 | 2.43e-54 |
early endosome | Hs | cellular component | 173 | 2.43e-54 |
late endosome | Hs | cellular component | 173 | 2.43e-54 |
endoplasmic reticulum membrane | Hs | cellular component | 172 | 6.07e-54 |
cytosol | Hs | cellular component | 173 | 2.43e-54 |
cytoskeleton | Hs | cellular component | 172 | 6.07e-54 |
plasma membrane | Hs | cellular component | 173 | 2.43e-54 |
focal adhesion | Hs | cellular component | 173 | 2.43e-54 |
cell cortex | Hs | cellular component | 172 | 6.07e-54 |
endosome membrane | Hs | cellular component | 173 | 2.43e-54 |
membrane | Hs | cellular component | 173 | 2.43e-54 |
myosin binding | Hs | molecular function | 172 | 6.07e-54 |
GDP binding | Hs | molecular function | 173 | 2.43e-54 |
protein domain specific binding | Hs | molecular function | 172 | 6.07e-54 |
lamellipodium | Hs | cellular component | 172 | 6.07e-54 |
cell junction | Hs | cellular component | 172 | 6.07e-54 |
axon | Hs | cellular component | 172 | 6.07e-54 |
midbody | Hs | cellular component | 172 | 6.07e-54 |
secretory granule membrane | Hs | cellular component | 172 | 6.07e-54 |
extrinsic component of cytoplasmic side of plasma membrane | Hs | cellular component | 172 | 6.07e-54 |
late endosome membrane | Hs | cellular component | 173 | 2.43e-54 |
vesicle | Hs | cellular component | 172 | 6.07e-54 |
cleavage furrow | Hs | cellular component | 173 | 2.43e-54 |
ruffle membrane | Hs | cellular component | 172 | 6.07e-54 |
cell projection | Hs | cellular component | 172 | 6.07e-54 |
dendritic spine | Hs | cellular component | 172 | 6.07e-54 |
apical junction complex | Hs | cellular component | 172 | 6.07e-54 |
Rho GDP-dissociation inhibitor binding | Hs | molecular function | 172 | 6.07e-54 |
extracellular exosome | Hs | cellular component | 173 | 2.43e-54 |
cell periphery | Hs | cellular component | 172 | 6.07e-54 |
ficolin-1-rich granule membrane | Hs | cellular component | 172 | 6.07e-54 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
GTPase activity | Pfam | molecular function | 4.8E-51 |
GTP binding | Pfam | molecular function | 4.8E-51 |
intracellular | ProSiteProfiles | cellular component | 23.037 |
small GTPase mediated signal transduction | ProSiteProfiles | biological process | 23.037 |