Aniseed - Gene card

Gene Card

Best human hits

HES1; HES2; HES4

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00000369

Gene Model ID

KH2012:KH.C1.159

Location

KhC1:682412..684277

Transcript Models and Sequences

KH2012:KH.C1.159.v1.A.nonSL3-1
KH2012:KH.C1.159.v1.A.nonSL4-1
KH2012:KH.C1.159.v1.A.nonSL5-1
KH2012:KH.C1.159.v1.R.nonSL1-1
KH2012:KH.C1.159.v1.R.nonSL2-1

External Database Gene Card

External database links

2 results

Database	Gene ID
ENSEMBL	ENSCING00000013835
NCBI Reference Sequence	NM_001078521.1

Collections

Gateway full ORF

2 results

Gene collection 1 (N. Satoh)

1 result

citb7o19

Plate: R1CiGC29d10

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Regulatory Regions

1 results

Ci-Hes-a -1624/-1410 REG00000342 [ regulatory_region (enhancer) ]

Gene Phylogeny

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Gene Annotations

InterPro

6 results

IPR Term	Analysis	Definition
HLH_DNA-bd_sf	Gene3D	Helix-loop-helix DNA-binding domain superfamily
bHLH_dom	ProSiteProfiles	Myc-type, basic helix-loop-helix (bHLH) domain
HLH_DNA-bd_sf	SUPERFAMILY	Helix-loop-helix DNA-binding domain superfamily
bHLH_dom	SMART	Myc-type, basic helix-loop-helix (bHLH) domain
bHLH_dom	CDD	Myc-type, basic helix-loop-helix (bHLH) domain
bHLH_dom	Pfam	Myc-type, basic helix-loop-helix (bHLH) domain

GOSlim

26 results

GO Term	Annotation Origin	Type
negative regulation of transcription from RNA polymerase II promoter	Orthology	biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Orthology	molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
DNA binding	Orthology	molecular function
double-stranded DNA binding	Blast	molecular function
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
protein binding	Blast	molecular function
intracellular	Blast	cellular component
nucleus	Orthology	cellular component
nucleoplasm	Blast	cellular component
cytoplasm	Blast	cellular component
transcription, DNA-templated	Orthology	biological process
regulation of transcription, DNA-templated	Orthology	biological process
multicellular organism development	Orthology	biological process
transcription factor binding	Blast	molecular function
protein homodimerization activity	Orthology	molecular function
sequence-specific DNA binding	Blast	molecular function
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
protein dimerization activity	Orthology	molecular function
central nervous system development	Orthology	biological process
gene expression	Orthology	biological process
neuron differentiation	Orthology	biological process
intracellular part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
developmental process	Orthology	biological process
enzyme binding	Blast	molecular function

GO (Orthology)

19 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function
DNA binding	Hs	molecular function
transcription factor activity, sequence-specific DNA binding	Hs	molecular function
nucleus	Hs	cellular component
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
protein homodimerization activity	Hs	molecular function
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
protein dimerization activity	Hs	molecular function
transcription factor complex	Hs	cellular component
central nervous system development	Hs	biological process
post-embryonic development	Hs	biological process
multicellular organism aging	Hs	biological process
gene expression	Hs	biological process
neuron differentiation	Hs	biological process
multicellular organism growth	Hs	biological process

GO (Blast)

18 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function	66.2	2.26e-13
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function	82.0	2.40e-18
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function	82.0	2.40e-18
DNA binding	Hs	molecular function	82.0	2.40e-18
double-stranded DNA binding	Hs	molecular function	66.2	2.26e-13
transcription factor activity, sequence-specific DNA binding	Hs	molecular function	82.0	2.40e-18
protein binding	Hs	molecular function	82.0	2.40e-18
intracellular	Hs	cellular component	82.0	2.40e-18
nucleus	Hs	cellular component	82.0	2.40e-18
nucleoplasm	Hs	cellular component	82.0	2.40e-18
cytoplasm	Hs	cellular component	82.0	2.40e-18
transcription factor binding	Hs	molecular function	82.0	2.40e-18
protein homodimerization activity	Hs	molecular function	82.0	2.40e-18
histone deacetylase binding	Hs	molecular function	82.0	2.40e-18
sequence-specific DNA binding	Hs	molecular function	82.0	2.40e-18
protein dimerization activity	Hs	molecular function	82.0	2.40e-18
chaperone binding	Hs	molecular function	82.0	2.40e-18
N-box binding	Hs	molecular function	82.0	2.40e-18

GO (InterProScan)