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GENE CARD

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Gene Card

Best human hits

MMP14; MMP16; MMP24

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00000571

Gene Model ID

KH2012:KH.C1.340

Location

KhC1:4879828..4894271

Transcript Models and Sequences

  KH2012:KH.C1.340.v1.A.SL1-1
KH2012:KH.C1.340.v1.A.SL2-1
KH2012:KH.C1.340.v1.A.SL3-1
KH2012:KH.C1.340.v1.A.SL4-1
KH2012:KH.C1.340.v2.A.SL1-2
KH2012:KH.C1.340.v2.A.SL2-2
KH2012:KH.C1.340.v2.A.SL3-2
KH2012:KH.C1.340.v2.A.SL4-2

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000005286
NCBI Reference Sequence XM_009864054.2
Collections

Gateway full ORF

2 results

cien45000

Plate: VES77_A11

cima829635

Plate: VES61_H18

Gene collection 1 (N. Satoh)

2 results

cicl057p10

Plate: R1CiGC14n20

cilv025d05

Plate: R1CiGC27k19

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

17 results

IPR Term Analysis Definition
Pept_M10_metallopeptidase Pfam Peptidase M10, metallopeptidase
Peptidoglycan-bd-like Pfam Peptidoglycan binding-like
Peptidase_Metallo SMART Peptidase, metallopeptidase
Pept_M10A PRINTS Peptidase M10A
PGBD-like_sf SUPERFAMILY PGBD-like superfamily
PGBDSf Gene3D PGBD superfamily
MMP14 PANTHER Matrix metalloproteinase-14
MetalloPept_cat_dom_sf Gene3D Metallopeptidase, catalytic domain superfamily
M10A_MMP CDD Peptidase M10A, catalytic domain
Hemopexin-like_repeat ProSiteProfiles Hemopexin-like repeats
Hemopexin-like_repeat Pfam Hemopexin-like repeats
Hemopexin-like_dom CDD Hemopexin-like domain
Pept_M10A PIRSF Peptidase M10A
Hemopexin-like_dom_sf SUPERFAMILY Hemopexin-like domain superfamily
Hemopexin-like_dom_sf Gene3D Hemopexin-like domain superfamily
Hemopexin-like_repeat SMART Hemopexin-like repeats
MMP15 PANTHER Matrix metalloproteinase-15

GOSlim

65 results

GO Term Annotation Origin Type
angiogenesis Orthology biological process
response to hypoxia Orthology biological process
metalloendopeptidase activity Orthology molecular function
serine-type endopeptidase activity Orthology molecular function
integrin binding Orthology molecular function
protein binding Orthology molecular function
extracellular region Orthology cellular component
extracellular space Orthology cellular component
nucleus Orthology cellular component
cytoplasm Orthology cellular component
Golgi apparatus Orthology cellular component
cytosol Orthology cellular component
plasma membrane Orthology cellular component
integral component of plasma membrane Orthology cellular component
focal adhesion Orthology cellular component
proteolysis Orthology biological process
response to oxidative stress Orthology biological process
cell adhesion Orthology biological process
enzyme activator activity Orthology molecular function
peptidase activity Orthology molecular function
metallopeptidase activity Orthology molecular function
zinc ion binding Orthology molecular function
cell surface Orthology cellular component
membrane Orthology cellular component
integral component of membrane Orthology cellular component
cell migration Orthology biological process
hydrolase activity Orthology molecular function
protein metabolic process Orthology biological process
cytoplasmic vesicle Orthology cellular component
melanosome Orthology cellular component
positive regulation of catalytic activity Orthology biological process
metal ion binding Orthology molecular function
cell motility Orthology biological process
head development Orthology biological process
extracellular exosome Orthology cellular component
cellular protein modification process Orthology biological process
reproductive process Orthology biological process
animal organ development Orthology biological process
cell proliferation Orthology biological process
anatomical structure morphogenesis Orthology biological process
Golgi apparatus part Orthology cellular component
intracellular organelle lumen Orthology cellular component
response to organic substance Orthology biological process
neurogenesis Orthology biological process
anatomical structure development Orthology biological process
cell differentiation Orthology biological process
positive regulation of hydrolase activity Orthology biological process
gene expression Orthology biological process
enzyme binding Orthology molecular function
cellular component organization Orthology biological process
catabolic process Orthology biological process
extracellular region part Orthology cellular component
Golgi membrane Orthology cellular component
anatomical structure formation involved in morphogenesis Orthology biological process
multicellular organism development Orthology biological process
response to stimulus Orthology biological process
endosome Orthology cellular component
cytoskeleton Orthology cellular component
cell adhesion molecule binding Orthology molecular function
immune system process Orthology biological process
negative regulation of signal transduction Orthology biological process
Notch signaling pathway Orthology biological process
sensory perception Orthology biological process
developmental process Orthology biological process
response to lipid Orthology biological process

GO (Orthology)

77 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
ossification Hs biological process
angiogenesis Hs biological process
ovarian follicle development Hs biological process
response to hypoxia Hs biological process
endothelial cell proliferation Hs biological process
endochondral ossification Hs biological process
metalloendopeptidase activity Hs molecular function
serine-type endopeptidase activity Hs molecular function
integrin binding Hs molecular function
protein binding Hs molecular function
extracellular region Hs cellular component
proteinaceous extracellular matrix Hs cellular component
extracellular space Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
Golgi apparatus Hs cellular component
Golgi lumen Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
integral component of plasma membrane Hs cellular component
focal adhesion Hs cellular component
proteolysis Hs biological process
response to oxidative stress Hs biological process
cell adhesion Hs biological process
enzyme activator activity Hs molecular function
peptidase activity Hs molecular function
metallopeptidase activity Hs molecular function
zinc ion binding Hs molecular function
male gonad development Hs biological process
response to mechanical stimulus Hs biological process
response to hormone Hs biological process
cell surface Hs cellular component
glial cell differentiation Hs biological process
positive regulation of myotube differentiation Hs biological process
positive regulation of peptidase activity Hs biological process
response to organic cyclic compound Hs biological process
membrane Hs cellular component
integral component of membrane Hs cellular component
cell migration Hs biological process
protein processing Hs biological process
peptidase activator activity Hs molecular function
hydrolase activity Hs molecular function
protein metabolic process Hs biological process
positive regulation of cell growth Hs biological process
lung development Hs biological process
positive regulation of cell migration Hs biological process
collagen catabolic process Hs biological process
extracellular matrix Hs cellular component
cytoplasmic vesicle Hs cellular component
zymogen activation Hs biological process
trans-Golgi network membrane Hs cellular component
endodermal cell differentiation Hs biological process
chondrocyte proliferation Hs biological process
melanosome Hs cellular component
positive regulation of catalytic activity Hs biological process
response to estrogen Hs biological process
cell-cell adhesion mediated by cadherin Hs biological process
macropinosome Hs cellular component
intermediate filament cytoskeleton Hs cellular component
cadherin binding Hs molecular function
positive regulation of B cell differentiation Hs biological process
negative regulation of Notch signaling pathway Hs biological process
metal ion binding Hs molecular function
embryonic cranial skeleton morphogenesis Hs biological process
branching morphogenesis of an epithelial tube Hs biological process
tissue remodeling Hs biological process
cell motility Hs biological process
detection of temperature stimulus involved in sensory perception of pain Hs biological process
negative regulation of focal adhesion assembly Hs biological process
head development Hs biological process
bone development Hs biological process
metalloaminopeptidase activity Hs molecular function
extracellular exosome Hs cellular component
neuronal stem cell population maintenance Hs biological process
response to odorant Hs biological process
cellular protein modification process Hs biological process
response to estradiol Hs biological process

GO (Blast)

34 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
metalloendopeptidase activity Hs molecular function 404 4.75e-133
serine-type endopeptidase activity Hs molecular function 397 8.44e-131
integrin binding Hs molecular function 397 8.44e-131
protein binding Hs molecular function 397 8.44e-131
extracellular region Hs cellular component 404 4.75e-133
proteinaceous extracellular matrix Hs cellular component 404 4.75e-133
extracellular space Hs cellular component 397 8.44e-131
nucleus Hs cellular component 397 8.44e-131
cytoplasm Hs cellular component 397 8.44e-131
Golgi apparatus Hs cellular component 384 4.20e-125
Golgi lumen Hs cellular component 404 4.75e-133
cytosol Hs cellular component 397 8.44e-131
plasma membrane Hs cellular component 404 4.75e-133
integral component of plasma membrane Hs cellular component 404 4.75e-133
focal adhesion Hs cellular component 397 8.44e-131
enzyme activator activity Hs molecular function 404 4.75e-133
peptidase activity Hs molecular function 404 4.75e-133
metallopeptidase activity Hs molecular function 404 4.75e-133
zinc ion binding Hs molecular function 404 4.75e-133
cell surface Hs cellular component 404 4.75e-133
membrane Hs cellular component 404 4.75e-133
integral component of membrane Hs cellular component 404 4.75e-133
peptidase activator activity Hs molecular function 397 8.44e-131
hydrolase activity Hs molecular function 404 4.75e-133
extracellular matrix Hs cellular component 404 4.75e-133
cytoplasmic vesicle Hs cellular component 397 8.44e-131
trans-Golgi network membrane Hs cellular component 384 4.20e-125
melanosome Hs cellular component 397 8.44e-131
macropinosome Hs cellular component 397 8.44e-131
intermediate filament cytoskeleton Hs cellular component 397 8.44e-131
cadherin binding Hs molecular function 384 4.20e-125
metal ion binding Hs molecular function 404 4.75e-133
metalloaminopeptidase activity Hs molecular function 404 4.75e-133
extracellular exosome Hs cellular component 384 4.20e-125

GO (InterProScan)

8 results

GO Term Analysis Type e-value
metalloendopeptidase activity PANTHER molecular function 7.4E-67
integral component of plasma membrane PANTHER cellular component 1.7E-150
proteolysis PANTHER biological process 7.4E-67
metallopeptidase activity Gene3D molecular function 1.4E-82
zinc ion binding PANTHER molecular function 7.4E-67
positive regulation of cell growth PANTHER biological process 7.4E-67
positive regulation of cell migration PANTHER biological process 7.4E-67
extracellular matrix Pfam cellular component 1.5E-28

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