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GENE CARD

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Gene Card

Best human hits

CEL; WAS; WASL

Unique Gene ID

Cirobu.g00000608

Gene Model ID

KH2012:KH.C1.374

Location

KhC1:3787444..3800164

Collections

Gateway full ORF

2 results

cien41460

Plate: VES76_G22

cien182135

Plate: VES98_O08

Gene collection 1 (N. Satoh)

2 results

cicl013l21

Plate: R1CiGC09n04

cieg038i23

Plate: R1CiGC21n11

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

15 results

IPR Term Analysis Definition
WH1/EVH1_dom SMART WH1/EVH1 domain
CRIB_dom SMART CRIB domain
CRIB_dom CDD CRIB domain
WASP_C SUPERFAMILY Wiscott-Aldrich syndrome protein, C-terminal
WH1/EVH1_dom ProSiteProfiles WH1/EVH1 domain
CRIB_dom Pfam CRIB domain
WH2_dom SMART WH2 domain
CRIB_dom_sf Gene3D CRIB domain superfamily
WH2_dom ProSiteProfiles WH2 domain
CRIB_dom ProSiteProfiles CRIB domain
WASPfam_EVH1 CDD WASP family, EVH1 domain
N-WASP PANTHER Neural Wiskott-Aldrich syndrome protein
WH2_dom Pfam WH2 domain
WH1/EVH1_dom Pfam WH1/EVH1 domain
PH-like_dom_sf Gene3D PH-like domain superfamily

GOSlim

49 results

GO Term Annotation Origin Type
actin binding Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
cytoskeleton Orthology cellular component
plasma membrane Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
defense response Orthology biological process
immune response Orthology biological process
cell cycle Orthology biological process
blood coagulation Orthology biological process
response to bacterium Orthology biological process
hydrolase activity Blast molecular function
protein kinase binding Orthology molecular function
lamellipodium Orthology cellular component
GTPase regulator activity Orthology molecular function
cytoplasmic vesicle Orthology cellular component
identical protein binding Orthology molecular function
regulation of catalytic activity Orthology biological process
cell division Orthology biological process
membrane organization Orthology biological process
extracellular exosome Orthology cellular component
cytoskeletal part Orthology cellular component
cell junction Orthology cellular component
organelle organization Orthology biological process
anatomical structure development Orthology biological process
cell projection assembly Orthology biological process
vesicle Orthology cellular component
organelle membrane Orthology cellular component
intracellular transport Orthology biological process
cytoplasmic part Orthology cellular component
cell periphery Orthology cellular component
intracellular organelle part Orthology cellular component
whole membrane Orthology cellular component
bounding membrane of organelle Orthology cellular component
enzyme binding Orthology molecular function
protein localization Orthology biological process
cellular protein localization Orthology biological process
cellular process Orthology biological process
immune system process Orthology biological process
cell surface receptor signaling pathway Orthology biological process
regulation of metabolic process Orthology biological process
oxidation-reduction process Orthology biological process
cell morphogenesis involved in neuron differentiation Orthology biological process
neuron projection morphogenesis Orthology biological process
innate immune response Orthology biological process
cell motility Orthology biological process

GO (Orthology)

61 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
actin binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
cytoskeleton Hs cellular component
actin filament Hs cellular component
plasma membrane Hs cellular component
cell-cell junction Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
vesicle budding from membrane Hs biological process
defense response Hs biological process
immune response Hs biological process
actin filament organization Hs biological process
cell cycle Hs biological process
blood coagulation Hs biological process
regulation of actin polymerization or depolymerization Hs biological process
actin polymerization or depolymerization Hs biological process
epidermis development Hs biological process
response to bacterium Hs biological process
regulation of lamellipodium assembly Hs biological process
vesicle membrane Hs cellular component
actin cytoskeleton Hs cellular component
vesicle organization Hs biological process
endosomal transport Hs biological process
SH3 domain binding Hs molecular function
protein kinase binding Hs molecular function
lamellipodium Hs cellular component
actin cytoskeleton organization Hs biological process
actin filament polymerization Hs biological process
actin filament-based movement Hs biological process
vesicle transport along actin filament Hs biological process
actin cap Hs cellular component
endocytic vesicle membrane Hs cellular component
GTPase regulator activity Hs molecular function
small GTPase binding Hs molecular function
cytoplasmic vesicle Hs cellular component
regulation of protein localization Hs biological process
cellular protein complex localization Hs biological process
T cell activation Hs biological process
identical protein binding Hs molecular function
phospholipase binding Hs molecular function
phagocytic vesicle Hs cellular component
ephrin receptor signaling pathway Hs biological process
Rac GTPase binding Hs molecular function
regulation of catalytic activity Hs biological process
T cell receptor signaling pathway Hs biological process
regulation of nitric-oxide synthase activity Hs biological process
cell division Hs biological process
positive regulation of filopodium assembly Hs biological process
regulation of stress fiber assembly Hs biological process
negative regulation of stress fiber assembly Hs biological process
spindle localization Hs biological process
dendritic spine morphogenesis Hs biological process
membrane organization Hs biological process
extracellular exosome Hs cellular component
cellular response to interferon-gamma Hs biological process
negative regulation of cell motility Hs biological process
positive regulation of clathrin-dependent endocytosis Hs biological process
positive regulation of Arp2/3 complex-mediated actin nucleation Hs biological process

GO (Blast)

26 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
actin binding Hs molecular function 272 2.15e-85
protein binding Hs molecular function 272 2.15e-85
nucleus Hs cellular component 258 6.07e-80
cytoplasm Hs cellular component 272 2.15e-85
cytosol Hs cellular component 272 2.15e-85
cytoskeleton Hs cellular component 272 2.15e-85
actin filament Hs cellular component 272 2.15e-85
plasma membrane Hs cellular component 258 6.07e-80
cell-cell junction Hs cellular component 272 2.15e-85
vesicle membrane Hs cellular component 272 2.15e-85
actin cytoskeleton Hs cellular component 272 2.15e-85
hydrolase activity Hs molecular function 52.4 5.08e-07
hydrolase activity, acting on ester bonds Hs molecular function 52.4 5.08e-07
SH3 domain binding Hs molecular function 272 2.15e-85
protein kinase binding Hs molecular function 272 2.15e-85
lamellipodium Hs cellular component 258 6.07e-80
actin cap Hs cellular component 258 6.07e-80
endocytic vesicle membrane Hs cellular component 258 6.07e-80
GTPase regulator activity Hs molecular function 272 2.15e-85
small GTPase binding Hs molecular function 272 2.15e-85
cytoplasmic vesicle Hs cellular component 258 6.07e-80
identical protein binding Hs molecular function 272 2.15e-85
phospholipase binding Hs molecular function 272 2.15e-85
phagocytic vesicle Hs cellular component 272 2.15e-85
Rac GTPase binding Hs molecular function 272 2.15e-85
extracellular exosome Hs cellular component 272 2.15e-85

GO (InterProScan)

3 results

GO Term Analysis Type e-value
actin binding PANTHER molecular function 2.6E-128
actin filament organization PANTHER biological process 2.6E-128
positive regulation of Arp2/3 complex-mediated actin nucleation PANTHER biological process 2.6E-128