Gene Card
Best human hits
FZD1; FZD2; FZD8
Unique Gene ID
Cirobu.g00000768
Gene Model ID
KH2012:KH.C1.520
Location
KhC1:2454865..2457040
Transcript Models and Sequences
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000013758 |
NCBI Reference Sequence | NM_001078345.1 |
cima831738
Plate: VES62_P03
cima860749
Plate: VES64_E18
citb5k21
Plate: R1CiGC29o10
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Frizzled_dom | SMART | Frizzled domain |
Frizzled_dom | ProSiteProfiles | Frizzled domain |
Frizzled_dom | Pfam | Frizzled domain |
Frizzled_dom_sf | SUPERFAMILY | Frizzled cysteine-rich domain superfamily |
Frizzled/SFRP | PANTHER | Frizzled/secreted frizzled-related protein |
Frizzled_dom_sf | Gene3D | Frizzled cysteine-rich domain superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
signal transducer activity | Blast | molecular function |
transmembrane signaling receptor activity | Orthology | molecular function |
G-protein coupled receptor activity | Orthology | molecular function |
receptor binding | Blast | molecular function |
protein binding | Orthology | molecular function |
cytoplasm | Orthology | cellular component |
Golgi apparatus | Blast | cellular component |
plasma membrane | Blast | cellular component |
focal adhesion | Blast | cellular component |
cell surface receptor signaling pathway | Orthology | biological process |
G-protein coupled receptor signaling pathway | Orthology | biological process |
cell-cell signaling | Orthology | biological process |
multicellular organism development | Orthology | biological process |
cell surface | Orthology | cellular component |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
ubiquitin protein ligase binding | Blast | molecular function |
extracellular region | Orthology | cellular component |
extracellular space | Orthology | cellular component |
nucleus | Orthology | cellular component |
negative regulation of cell proliferation | Orthology | biological process |
positive regulation of gene expression | Orthology | biological process |
cell differentiation | Orthology | biological process |
negative regulation of Wnt signaling pathway | Orthology | biological process |
positive regulation of apoptotic process | Orthology | biological process |
negative regulation of canonical Wnt signaling pathway | Orthology | biological process |
positive regulation of canonical Wnt signaling pathway | Orthology | biological process |
system development | Orthology | biological process |
organelle organization | Orthology | biological process |
membrane organization | Orthology | biological process |
response to organic substance | Orthology | biological process |
animal organ development | Orthology | biological process |
cellular component organization | Orthology | biological process |
regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
regulation of signal transduction | Orthology | biological process |
anatomical structure morphogenesis | Orthology | biological process |
regulation of molecular function | Orthology | biological process |
transcription factor activity, sequence-specific DNA binding | Orthology | molecular function |
whole membrane | Blast | cellular component |
intracellular organelle part | Blast | cellular component |
cytoplasmic vesicle | Blast | cellular component |
bounding membrane of organelle | Blast | cellular component |
plasma membrane part | Blast | cellular component |
macromolecular complex | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
signal transducer activity | Hs | molecular function | 109 | 1.06e-28 |
transmembrane signaling receptor activity | Hs | molecular function | 109 | 1.06e-28 |
G-protein coupled receptor activity | Hs | molecular function | 109 | 1.06e-28 |
receptor binding | Hs | molecular function | 109 | 1.06e-28 |
frizzled binding | Hs | molecular function | 105 | 2.24e-27 |
protein binding | Hs | molecular function | 109 | 1.06e-28 |
cytoplasm | Hs | cellular component | 107 | 5.68e-28 |
Golgi apparatus | Hs | cellular component | 109 | 1.06e-28 |
plasma membrane | Hs | cellular component | 109 | 1.06e-28 |
focal adhesion | Hs | cellular component | 107 | 5.68e-28 |
cell surface | Hs | cellular component | 105 | 2.24e-27 |
membrane | Hs | cellular component | 109 | 1.06e-28 |
integral component of membrane | Hs | cellular component | 109 | 1.06e-28 |
Wnt-protein binding | Hs | molecular function | 109 | 1.06e-28 |
PDZ domain binding | Hs | molecular function | 109 | 1.06e-28 |
clathrin-coated endocytic vesicle membrane | Hs | cellular component | 107 | 5.68e-28 |
ubiquitin protein ligase binding | Hs | molecular function | 109 | 1.06e-28 |
Wnt-activated receptor activity | Hs | molecular function | 109 | 1.06e-28 |
Wnt-Frizzled-LRP5/6 complex | Hs | cellular component | 109 | 1.06e-28 |
Wnt signalosome | Hs | cellular component | 105 | 2.24e-27 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein binding | SUPERFAMILY | molecular function | 4.45E-35 |