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Gene Card

Best human hits

HDAC4; HDAC5; HDAC9

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00001339

Gene Model ID

KH2012:KH.C10.140

Location

KhC10:1858581..1875433

Transcript Models and Sequences

  KH2012:KH.C10.140.v1.A.SL1-1
KH2012:KH.C10.140.v1.A.SL2-1
KH2012:KH.C10.140.v2.A.SL3-1

External Database Gene Card

External database links

2 results

Database Gene ID
NCBI Reference Sequence XM_002128106.3
NCBI Reference Sequence XM_018813760.1
Collections

Gateway full ORF

2 results

cien88340

Plate: VES84_K05

cima877781

Plate: VES68_J05

Gene collection 1 (N. Satoh)

2 results

citb035d12

Plate: R1CiGC32m07

citb039n10

Plate: R1CiGC32d16

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

6 results

IPR Term Analysis Definition
His_deacetylse_dom_sf Gene3D Histone deacetylase domain superfamily
His_deacetylse PRINTS Histone deacetylase superfamily
Ureohydrolase_dom_sf SUPERFAMILY Ureohydrolase domain superfamily
His_deacetylse_dom Pfam Histone deacetylase domain
His_deacetylse PANTHER Histone deacetylase superfamily
Histone_deAcase_II_euk PIRSF Histone deacetylase class II, eukaryotic

GOSlim

64 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
DNA binding Orthology molecular function
chromatin binding Orthology molecular function
transcription corepressor activity Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
Golgi apparatus Orthology cellular component
cytosol Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
nervous system development Orthology biological process
heart development Orthology biological process
transcription factor binding Orthology molecular function
zinc ion binding Orthology molecular function
positive regulation of cell proliferation Orthology biological process
negative regulation of cell proliferation Orthology biological process
nuclear speck Orthology cellular component
hydrolase activity Orthology molecular function
protein kinase binding Orthology molecular function
neuron differentiation Orthology biological process
identical protein binding Orthology molecular function
sequence-specific DNA binding Orthology molecular function
transcription regulatory region DNA binding Orthology molecular function
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
metal ion binding Orthology molecular function
nucleoplasm part Orthology cellular component
macromolecular complex Orthology cellular component
system development Orthology biological process
response to organic substance Orthology biological process
cell development Orthology biological process
organelle organization Orthology biological process
cellular protein modification process Orthology biological process
intracellular part Orthology cellular component
defense response Orthology biological process
cell projection assembly Orthology biological process
anatomical structure development Orthology biological process
cell differentiation Orthology biological process
intracellular signal transduction Orthology biological process
response to stimulus Orthology biological process
cytoplasmic part Orthology cellular component
organelle part Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
immune system process Orthology biological process
animal organ development Orthology biological process
synapse Orthology cellular component
cellular response to organic substance Orthology biological process
regulation of gene expression Orthology biological process
cellular process Orthology biological process
cytoskeletal part Orthology cellular component
enzyme binding Orthology molecular function
regulation of molecular function Orthology biological process
transcription factor activity, sequence-specific DNA binding Orthology molecular function
positive regulation of apoptotic process Orthology biological process
response to lipopolysaccharide Orthology biological process
cell migration Orthology biological process
angiogenesis Orthology biological process
blood vessel morphogenesis Orthology biological process
protein modification by small protein conjugation Orthology biological process
ubiquitin-like protein transferase activity Orthology molecular function
negative regulation of signal transduction Orthology biological process

GO (Orthology)

86 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
histone deacetylase complex Hs cellular component
negative regulation of transcription from RNA polymerase II promoter Hs biological process
core promoter binding Hs molecular function
RNA polymerase II transcription factor binding Hs molecular function
skeletal system development Hs biological process
response to amphetamine Hs biological process
osteoblast development Hs biological process
DNA binding Hs molecular function
chromatin binding Hs molecular function
transcription corepressor activity Hs molecular function
histone deacetylase activity Hs molecular function
protein kinase C binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
transcription factor complex Hs cellular component
cytoplasm Hs cellular component
Golgi apparatus Hs cellular component
cytosol Hs cellular component
chromatin organization Hs biological process
chromatin remodeling Hs biological process
chromatin silencing Hs biological process
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
protein deacetylation Hs biological process
inflammatory response Hs biological process
nervous system development Hs biological process
heart development Hs biological process
transcription factor binding Hs molecular function
zinc ion binding Hs molecular function
positive regulation of cell proliferation Hs biological process
negative regulation of cell proliferation Hs biological process
positive regulation of lamellipodium assembly Hs biological process
regulation of myotube differentiation Hs biological process
regulation of cardiac muscle contraction by calcium ion signaling Hs biological process
response to activity Hs biological process
histone deacetylation Hs biological process
nuclear speck Hs cellular component
hydrolase activity Hs molecular function
transcriptional repressor complex Hs cellular component
protein kinase binding Hs molecular function
sarcomere Hs cellular component
Z disc Hs cellular component
neuron differentiation Hs biological process
B cell differentiation Hs biological process
potassium ion binding Hs molecular function
neuromuscular junction Hs cellular component
A band Hs cellular component
NAD-dependent histone deacetylase activity (H3-K14 specific) Hs molecular function
cellular response to insulin stimulus Hs biological process
protein deacetylase activity Hs molecular function
activating transcription factor binding Hs molecular function
histone methyltransferase complex Hs cellular component
regulation of gene expression, epigenetic Hs biological process
B cell activation Hs biological process
response to cocaine Hs biological process
response to drug Hs biological process
actomyosin Hs cellular component
identical protein binding Hs molecular function
histone deacetylase binding Hs molecular function
regulation of protein binding Hs biological process
negative regulation of sequence-specific DNA binding transcription factor activity Hs biological process
positive regulation of neuron apoptotic process Hs biological process
sequence-specific DNA binding Hs molecular function
transcription regulatory region DNA binding Hs molecular function
negative regulation of osteoblast differentiation Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
metal ion binding Hs molecular function
regulation of skeletal muscle fiber development Hs biological process
positive regulation of sequence-specific DNA binding transcription factor activity Hs biological process
repressing transcription factor binding Hs molecular function
histone H3 deacetylation Hs biological process
cellular response to lipopolysaccharide Hs biological process
cellular response to mechanical stimulus Hs biological process
cellular response to tumor necrosis factor Hs biological process
positive regulation of cell migration involved in sprouting angiogenesis Hs biological process
negative regulation of pri-miRNA transcription from RNA polymerase II promoter Hs biological process
promoter-specific chromatin binding Hs molecular function
vasculogenesis Hs biological process
cell-cell junction assembly Hs biological process
protein sumoylation Hs biological process
SUMO transferase activity Hs molecular function
14-3-3 protein binding Hs molecular function
negative regulation of NIK/NF-kappaB signaling Hs biological process

GO (Blast)

38 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
histone deacetylase complex Hs cellular component 519 1.54e-166
core promoter binding Hs molecular function 472 1.28e-148
RNA polymerase II transcription factor binding Hs molecular function 472 1.28e-148
DNA binding Hs molecular function 472 1.28e-148
chromatin binding Hs molecular function 472 1.28e-148
transcription corepressor activity Hs molecular function 519 1.54e-166
histone deacetylase activity Hs molecular function 519 1.54e-166
protein kinase C binding Hs molecular function 519 1.54e-166
protein binding Hs molecular function 519 1.54e-166
nucleus Hs cellular component 519 1.54e-166
nucleoplasm Hs cellular component 519 1.54e-166
transcription factor complex Hs cellular component 519 1.54e-166
cytoplasm Hs cellular component 519 1.54e-166
Golgi apparatus Hs cellular component 438 1.73e-135
cytosol Hs cellular component 472 1.28e-148
transcription factor binding Hs molecular function 519 1.54e-166
zinc ion binding Hs molecular function 472 1.28e-148
nuclear speck Hs cellular component 438 1.73e-135
hydrolase activity Hs molecular function 519 1.54e-166
transcriptional repressor complex Hs cellular component 472 1.28e-148
protein kinase binding Hs molecular function 472 1.28e-148
sarcomere Hs cellular component 472 1.28e-148
Z disc Hs cellular component 472 1.28e-148
potassium ion binding Hs molecular function 472 1.28e-148
neuromuscular junction Hs cellular component 472 1.28e-148
A band Hs cellular component 472 1.28e-148
NAD-dependent histone deacetylase activity (H3-K14 specific) Hs molecular function 519 1.54e-166
protein deacetylase activity Hs molecular function 519 1.54e-166
activating transcription factor binding Hs molecular function 472 1.28e-148
histone methyltransferase complex Hs cellular component 519 1.54e-166
actomyosin Hs cellular component 472 1.28e-148
identical protein binding Hs molecular function 472 1.28e-148
histone deacetylase binding Hs molecular function 519 1.54e-166
sequence-specific DNA binding Hs molecular function 472 1.28e-148
transcription regulatory region DNA binding Hs molecular function 472 1.28e-148
metal ion binding Hs molecular function 519 1.54e-166
repressing transcription factor binding Hs molecular function 519 1.54e-166
promoter-specific chromatin binding Hs molecular function 472 1.28e-148

GO (InterProScan)

4 results

GO Term Analysis Type e-value
histone deacetylase complex PIRSF cellular component 9.2E-223
histone deacetylase activity PIRSF molecular function 9.2E-223
chromatin organization PIRSF biological process 9.2E-223
histone deacetylation PIRSF biological process 9.2E-223

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