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Gene Card

Best human hits

SLC8A1; SLC8A2; SLC8A3

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00001452

Gene Model ID

KH2012:KH.C10.246

Location

KhC10:3786179..3797684

Transcript Models and Sequences

  KH2012:KH.C10.246.v1.A.SL2-1
KH2012:KH.C10.246.v2.A.SL1-1
KH2012:KH.C10.246.v3.A.SL3-1

External Database Gene Card

External database links

3 results

Database Gene ID
ENSEMBL ENSCING00000006261
NCBI Reference Sequence XM_002126723.4
NCBI Reference Sequence XM_018813637.1
Collections

Gateway full ORF

1 result

cien70188

Plate: VES81_E07

Gene collection 1 (N. Satoh)

2 results

cilv006a12

Plate: R1CiGC25k16

citb047j24

Plate: R1CiGC45b04

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

8 results

IPR Term Analysis Definition
CalX-like_sf Gene3D CalX-like domain superfamily
Na_Ca_Ex PRINTS Sodium/calcium exchanger protein
CalX-like_sf SUPERFAMILY CalX-like domain superfamily
Na_Ca_Ex_C-exten Pfam Sodium/calcium exchanger domain, C-terminal extension
Calx_beta Pfam Na-Ca exchanger/integrin-beta4
NaCa_Exmemb Pfam Sodium/calcium exchanger membrane region
Calx_beta SMART Na-Ca exchanger/integrin-beta4
Na_Ca_Ex TIGRFAM Sodium/calcium exchanger protein

GOSlim

55 results

GO Term Annotation Origin Type
response to hypoxia Orthology biological process
calcium ion binding Orthology molecular function
protein binding Orthology molecular function
calmodulin binding Orthology molecular function
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
mitochondrion Orthology cellular component
endoplasmic reticulum Orthology cellular component
endoplasmic reticulum membrane Orthology cellular component
microtubule Orthology cellular component
plasma membrane Orthology cellular component
integral component of plasma membrane Orthology cellular component
ion transport Orthology biological process
sodium ion transport Orthology biological process
cell communication Orthology biological process
cytoskeletal protein binding Orthology molecular function
membrane Orthology cellular component
integral component of membrane Orthology cellular component
basolateral plasma membrane Orthology cellular component
metal ion transport Orthology biological process
cell junction Orthology cellular component
intrinsic component of plasma membrane Orthology cellular component
cell projection Orthology cellular component
neuronal cell body Orthology cellular component
postsynaptic membrane Orthology cellular component
metal ion binding Orthology molecular function
perinuclear region of cytoplasm Orthology cellular component
transmembrane transport Orthology biological process
animal organ development Orthology biological process
immune system process Orthology biological process
cell differentiation Orthology biological process
whole membrane Orthology cellular component
mitochondrial membrane Orthology cellular component
bounding membrane of organelle Orthology cellular component
cellular process Orthology biological process
cell Orthology cellular component
nervous system process Orthology biological process
response to organic substance Orthology biological process
intracellular signal transduction Orthology biological process
brain development Orthology biological process
organelle part Orthology cellular component
cytoplasmic part Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
plasma membrane part Orthology cellular component
synapse Orthology cellular component
response to oxidative stress Orthology biological process
nervous system development Orthology biological process
postsynapse Orthology cellular component
chemical synaptic transmission Orthology biological process
regulation of signaling Orthology biological process
neurogenesis Orthology biological process
central nervous system development Orthology biological process
cell development Orthology biological process
heart development Orthology biological process
cellular response to stress Orthology biological process

GO (Orthology)

84 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
response to hypoxia Hs biological process
regulation of heart rate Hs biological process
regulation of sodium ion transport Hs biological process
hematopoietic progenitor cell differentiation Hs biological process
calcium:sodium antiporter activity Hs molecular function
calcium ion binding Hs molecular function
protein binding Hs molecular function
calmodulin binding Hs molecular function
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
mitochondrion Hs cellular component
mitochondrial outer membrane Hs cellular component
endoplasmic reticulum Hs cellular component
endoplasmic reticulum membrane Hs cellular component
microtubule Hs cellular component
plasma membrane Hs cellular component
integral component of plasma membrane Hs cellular component
ion transport Hs biological process
sodium ion transport Hs biological process
calcium ion transport Hs biological process
mitochondrial calcium ion transmembrane transport Hs biological process
cellular calcium ion homeostasis Hs biological process
cellular sodium ion homeostasis Hs biological process
muscle contraction Hs biological process
cell communication Hs biological process
positive regulation of cytosolic calcium ion concentration Hs biological process
response to nutrient Hs biological process
learning Hs biological process
memory Hs biological process
cytoskeletal protein binding Hs molecular function
response to glucose Hs biological process
regulation of cell communication by electrical coupling Hs biological process
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion Hs biological process
regulation of cardiac muscle contraction by calcium ion signaling Hs biological process
intercalated disc Hs cellular component
antiporter activity Hs molecular function
calcium:cation antiporter activity Hs molecular function
membrane Hs cellular component
integral component of membrane Hs cellular component
basolateral plasma membrane Hs cellular component
sarcoplasm Hs cellular component
telencephalon development Hs biological process
metal ion transport Hs biological process
Z disc Hs cellular component
cell junction Hs cellular component
T-tubule Hs cellular component
dendrite Hs cellular component
positive regulation of bone mineralization Hs biological process
ankyrin binding Hs molecular function
intrinsic component of plasma membrane Hs cellular component
neuromuscular junction Hs cellular component
response to ATP Hs biological process
sodium ion transmembrane transport Hs biological process
sarcolemma Hs cellular component
response to drug Hs biological process
response to hydrogen peroxide Hs biological process
myelination Hs biological process
cell projection Hs cellular component
neuronal cell body Hs cellular component
dendritic spine Hs cellular component
dendritic shaft Hs cellular component
perikaryon Hs cellular component
ion channel binding Hs molecular function
postsynaptic membrane Hs cellular component
metal ion binding Hs molecular function
regulation of short-term neuronal synaptic plasticity Hs biological process
perinuclear region of cytoplasm Hs cellular component
oligodendrocyte differentiation Hs biological process
negative regulation of cytosolic calcium ion concentration Hs biological process
mitochondrial calcium ion homeostasis Hs biological process
regulation of calcium ion transport Hs biological process
cardiac muscle cell development Hs biological process
calcium ion homeostasis Hs biological process
transmembrane transport Hs biological process
cardiac muscle contraction Hs biological process
regulation of postsynaptic membrane potential Hs biological process
long-term synaptic potentiation Hs biological process
calcium ion import Hs biological process
calcium ion transmembrane transport Hs biological process
cellular response to hypoxia Hs biological process
calcium ion import across plasma membrane Hs biological process
sodium ion import across plasma membrane Hs biological process
ion antiporter activity involved in regulation of postsynaptic membrane potential Hs molecular function
regulation of cardiac conduction Hs biological process

GO (Blast)

39 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
calcium:sodium antiporter activity Hs molecular function 1068 0.0
calcium ion binding Hs molecular function 1068 0.0
protein binding Hs molecular function 1068 0.0
calmodulin binding Hs molecular function 1068 0.0
nucleoplasm Hs cellular component 1068 0.0
cytoplasm Hs cellular component 1055 0.0
mitochondrion Hs cellular component 1068 0.0
mitochondrial outer membrane Hs cellular component 1055 0.0
endoplasmic reticulum Hs cellular component 1055 0.0
endoplasmic reticulum membrane Hs cellular component 1055 0.0
microtubule Hs cellular component 1068 0.0
plasma membrane Hs cellular component 1068 0.0
integral component of plasma membrane Hs cellular component 1068 0.0
cytoskeletal protein binding Hs molecular function 1068 0.0
intercalated disc Hs cellular component 1068 0.0
antiporter activity Hs molecular function 1068 0.0
calcium:cation antiporter activity Hs molecular function 1055 0.0
membrane Hs cellular component 1068 0.0
integral component of membrane Hs cellular component 1068 0.0
basolateral plasma membrane Hs cellular component 1013 0.0
sarcoplasm Hs cellular component 1055 0.0
Z disc Hs cellular component 1068 0.0
cell junction Hs cellular component 1055 0.0
T-tubule Hs cellular component 1068 0.0
dendrite Hs cellular component 1055 0.0
ankyrin binding Hs molecular function 1068 0.0
intrinsic component of plasma membrane Hs cellular component 1055 0.0
neuromuscular junction Hs cellular component 1055 0.0
sarcolemma Hs cellular component 1068 0.0
cell projection Hs cellular component 1068 0.0
neuronal cell body Hs cellular component 1055 0.0
dendritic spine Hs cellular component 1068 0.0
dendritic shaft Hs cellular component 1068 0.0
perikaryon Hs cellular component 1055 0.0
ion channel binding Hs molecular function 1068 0.0
postsynaptic membrane Hs cellular component 1068 0.0
metal ion binding Hs molecular function 1068 0.0
perinuclear region of cytoplasm Hs cellular component 1055 0.0
ion antiporter activity involved in regulation of postsynaptic membrane potential Hs molecular function 1068 0.0

GO (InterProScan)

5 results

GO Term Analysis Type e-value
calcium:sodium antiporter activity PRINTS molecular function 1.5E-23
calcium ion transport PRINTS biological process 1.5E-23
cell communication SMART biological process 2.2E-42
membrane PRINTS cellular component 1.5E-23
transmembrane transport Pfam biological process 8.4E-30

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