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GENE CARD

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Gene Card

Best human hits

SIX1; SIX3; SIX6

Unique Gene ID

Cirobu.g00001582

Gene Model ID

KH2012:KH.C10.367

Location

KhC10:809959..812548

Transcript Models and Sequences

  KH2012:KH.C10.367.v1.A.ND1-1

External Database Gene Card

External database links

1 result

Database Gene ID
ENSEMBL ENSCING00000005828
Collections

Gene collection 1 (N. Satoh)

1 result

cicl021e08

Plate: R1CiGC11m13

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

6 results

IPR Term Analysis Definition
Homeobox_dom SMART Homeobox domain
Homeobox_dom Pfam Homeobox domain
SIX1_SD Pfam Homeobox protein SIX1, N-terminal SD domain
Homeobox-like_sf SUPERFAMILY Homeobox-like domain superfamily
Homeobox_dom ProSiteProfiles Homeobox domain
Homeobox_dom CDD Homeobox domain

GOSlim

42 results

GO Term Annotation Origin Type
RNA polymerase II core promoter proximal region sequence-specific DNA binding Blast molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
DNA binding Orthology molecular function
chromatin binding Blast molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcription coactivator activity Orthology molecular function
receptor binding Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleolus Blast cellular component
cytoplasm Blast cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
transcription from RNA polymerase II promoter Orthology biological process
apoptotic process Orthology biological process
multicellular organism development Orthology biological process
brain development Orthology biological process
visual perception Orthology biological process
cell proliferation Orthology biological process
negative regulation of Wnt signaling pathway Orthology biological process
regulation of cell proliferation Orthology biological process
sequence-specific DNA binding Orthology molecular function
transcription regulatory region DNA binding Blast molecular function
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
animal organ development Orthology biological process
generation of neurons Orthology biological process
anatomical structure development Orthology biological process
RNA polymerase II regulatory region sequence-specific DNA binding Orthology molecular function
transcription factor binding Orthology molecular function
cell development Orthology biological process
anatomical structure morphogenesis Orthology biological process
intracellular protein transport Orthology biological process
establishment of protein localization to organelle Orthology biological process
enzyme binding Orthology molecular function
neuron differentiation Orthology biological process
cell differentiation Orthology biological process
cell migration Orthology biological process
cell division Orthology biological process
intracellular part Blast cellular component
macromolecular complex Blast cellular component

GO (Orthology)

48 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
protein import into nucleus, translocation Hs biological process
RNA polymerase II distal enhancer sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function
transcription corepressor binding Hs molecular function
eye development Hs biological process
epithelial cell maturation Hs biological process
lens development in camera-type eye Hs biological process
optic vesicle morphogenesis Hs biological process
DNA binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function
transcription coactivator activity Hs molecular function
receptor binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
regulation of transcription from RNA polymerase II promoter Hs biological process
transcription from RNA polymerase II promoter Hs biological process
protein import into nucleus Hs biological process
multicellular organism development Hs biological process
brain development Hs biological process
visual perception Hs biological process
animal organ morphogenesis Hs biological process
proximal/distal axis specification Hs biological process
neuroblast differentiation Hs biological process
diencephalon development Hs biological process
telencephalon development Hs biological process
forebrain anterior/posterior pattern specification Hs biological process
forebrain dorsal/ventral pattern formation Hs biological process
cell proliferation in forebrain Hs biological process
pituitary gland development Hs biological process
negative regulation of Wnt signaling pathway Hs biological process
regulation of cell proliferation Hs biological process
histone deacetylase binding Hs molecular function
camera-type eye development Hs biological process
sequence-specific DNA binding Hs molecular function
negative regulation of neuron differentiation Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
circadian behavior Hs biological process
regulation of neural retina development Hs biological process
lens fiber cell differentiation Hs biological process
neuroblast migration Hs biological process
regulation of neuroblast proliferation Hs biological process
apoptotic process involved in development Hs biological process
regulation of neural precursor cell proliferation Hs biological process

GO (Blast)

21 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function 265 5.20e-87
RNA polymerase II distal enhancer sequence-specific DNA binding Hs molecular function 326 3.39e-110
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 326 3.39e-110
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function 265 5.20e-87
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function 326 3.39e-110
transcription corepressor binding Hs molecular function 326 3.39e-110
transcription coactivator binding Hs molecular function 265 5.20e-87
DNA binding Hs molecular function 326 3.39e-110
chromatin binding Hs molecular function 265 5.20e-87
transcription factor activity, sequence-specific DNA binding Hs molecular function 326 3.39e-110
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function 326 3.39e-110
transcription coactivator activity Hs molecular function 326 3.39e-110
receptor binding Hs molecular function 326 3.39e-110
protein binding Hs molecular function 326 3.39e-110
nucleus Hs cellular component 326 3.39e-110
transcription factor complex Hs cellular component 265 5.20e-87
nucleolus Hs cellular component 265 5.20e-87
cytoplasm Hs cellular component 265 5.20e-87
histone deacetylase binding Hs molecular function 326 3.39e-110
sequence-specific DNA binding Hs molecular function 326 3.39e-110
transcription regulatory region DNA binding Hs molecular function 265 5.20e-87

GO (InterProScan)

1 result

GO Term Analysis Type e-value
DNA binding SUPERFAMILY molecular function 4.18E-16