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Gene Card

Best human hits

CBL; CBLB; CBLC

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00001585

Gene Model ID

KH2012:KH.C10.37

Location

KhC10:196052..211445

Transcript Models and Sequences

  KH2012:KH.C10.37.v2.B.SL1-1
KH2012:KH.C10.37.v2.B.SL2-1
KH2012:KH.C10.37.v3.B.SL3-1

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000002655
ENSEMBL ENSCING00000024513
Collections

Gateway full ORF

2 results

cien98965

Plate: VES85_B19

cien207393

Plate: VES102_I12

Gene collection 1 (N. Satoh)

3 results

cieg002l12

Plate: R1CiGC15b12

cieg014m16

Plate: R1CiGC17n13

cicl051n21

Plate: R1CiGC14e15

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

15 results

IPR Term Analysis Definition
EF-hand-dom_pair SUPERFAMILY EF-hand domain pair
SH2_dom_sf Gene3D SH2 domain superfamily
Znf_RING_CS ProSitePatterns Zinc finger, RING-type, conserved site
Znf_RING/FYVE/PHD Gene3D Zinc finger, RING/FYVE/PHD-type
Adaptor_Cbl_SH2-like CDD Adaptor protein Cbl, SH2-like domain
Znf_RING SMART Zinc finger, RING-type
Adaptor_Cbl_N_hlx Pfam Adaptor protein Cbl, N-terminal helical
Adaptor_Cbl_N_dom_sf Gene3D Adaptor protein Cbl, N-terminal domain superfamily
Adaptor_Cbl_EF_hand-like Pfam Adaptor protein Cbl, EF hand-like
Cbl_PTB ProSiteProfiles Adaptor protein Cbl, PTB domain
SH2_dom_sf SUPERFAMILY SH2 domain superfamily
Adaptor_Cbl_N_dom_sf SUPERFAMILY Adaptor protein Cbl, N-terminal domain superfamily
Znf_RING ProSiteProfiles Zinc finger, RING-type
Adaptor_Cbl_SH2-like Pfam Adaptor protein Cbl, SH2-like domain
Adaptor_Cbl PANTHER Adaptor protein Cbl

GOSlim

55 results

GO Term Annotation Origin Type
protein polyubiquitination Orthology biological process
transcription factor activity, sequence-specific DNA binding Orthology molecular function
ubiquitin-protein transferase activity Orthology molecular function
signal transducer activity Orthology molecular function
calcium ion binding Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
plasma membrane Orthology cellular component
focal adhesion Orthology cellular component
regulation of transcription, DNA-templated Orthology biological process
proteolysis Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
signal transduction Orthology biological process
cell surface receptor signaling pathway Orthology biological process
zinc ion binding Orthology molecular function
membrane Orthology cellular component
protein ubiquitination Orthology biological process
transferase activity Orthology molecular function
cytokine-mediated signaling pathway Orthology biological process
protein kinase binding Orthology molecular function
regulation of signaling Orthology biological process
axon Orthology cellular component
negative regulation of apoptotic process Orthology biological process
membrane raft Orthology cellular component
metal ion binding Orthology molecular function
perinuclear region of cytoplasm Orthology cellular component
membrane organization Orthology biological process
extracellular exosome Orthology cellular component
receptor binding Orthology molecular function
intracellular protein transport Orthology biological process
establishment of protein localization to organelle Orthology biological process
transmembrane signaling receptor activity Orthology molecular function
regulation of catalytic activity Orthology biological process
protein kinase activity Orthology molecular function
negative regulation of signal transduction Orthology biological process
cellular response to organic substance Orthology biological process
reproductive process Orthology biological process
animal organ development Orthology biological process
intracellular signal transduction Orthology biological process
positive regulation of signal transduction Orthology biological process
response to stimulus Orthology biological process
plasma membrane region Orthology cellular component
macromolecular complex Orthology cellular component
cell projection part Orthology cellular component
response to stress Orthology biological process
lysosome Orthology cellular component
protein serine/threonine kinase activity Orthology molecular function
cell adhesion molecule binding Orthology molecular function
response to organic substance Orthology biological process
organelle organization Orthology biological process
cell death Orthology biological process
negative regulation of cell death Orthology biological process

GO (Orthology)

64 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
protein polyubiquitination Hs biological process
phosphotyrosine residue binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
ubiquitin-protein transferase activity Hs molecular function
signal transducer activity Hs molecular function
epidermal growth factor receptor binding Hs molecular function
calcium ion binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
focal adhesion Hs cellular component
regulation of transcription, DNA-templated Hs biological process
proteolysis Hs biological process
ubiquitin-dependent protein catabolic process Hs biological process
protein monoubiquitination Hs biological process
NLS-bearing protein import into nucleus Hs biological process
cellular response to DNA damage stimulus Hs biological process
signal transduction Hs biological process
cell surface receptor signaling pathway Hs biological process
epidermal growth factor receptor signaling pathway Hs biological process
negative regulation of epidermal growth factor-activated receptor activity Hs biological process
transforming growth factor beta receptor signaling pathway Hs biological process
zinc ion binding Hs molecular function
fibroblast growth factor receptor signaling pathway Hs biological process
male gonad development Hs biological process
response to gamma radiation Hs biological process
positive regulation of phosphatidylinositol 3-kinase signaling Hs biological process
response to activity Hs biological process
membrane Hs cellular component
protein ubiquitination Hs biological process
flotillin complex Hs cellular component
transferase activity Hs molecular function
SH3 domain binding Hs molecular function
cytokine-mediated signaling pathway Hs biological process
protein kinase binding Hs molecular function
regulation of signaling Hs biological process
axon Hs cellular component
growth cone Hs cellular component
receptor tyrosine kinase binding Hs molecular function
phosphatidylinositol 3-kinase regulatory subunit binding Hs molecular function
negative regulation of epidermal growth factor receptor signaling pathway Hs biological process
response to starvation Hs biological process
mast cell granule Hs cellular component
negative regulation of apoptotic process Hs biological process
negative regulation of MAP kinase activity Hs biological process
membrane raft Hs cellular component
cadherin binding Hs molecular function
response to ethanol Hs biological process
positive regulation of epidermal growth factor receptor signaling pathway Hs biological process
response to antibiotic Hs biological process
metal ion binding Hs molecular function
ephrin receptor binding Hs molecular function
positive regulation of receptor-mediated endocytosis Hs biological process
perinuclear region of cytoplasm Hs cellular component
membrane organization Hs biological process
ubiquitin protein ligase activity Hs molecular function
extracellular exosome Hs cellular component
neuron death Hs biological process
cellular response to epidermal growth factor stimulus Hs biological process
negative regulation of neuron death Hs biological process
protein tyrosine kinase binding Hs molecular function

GO (Blast)

32 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
phosphotyrosine residue binding Hs molecular function 617 0.0
transcription factor activity, sequence-specific DNA binding Hs molecular function 617 0.0
ubiquitin-protein transferase activity Hs molecular function 617 0.0
signal transducer activity Hs molecular function 617 0.0
epidermal growth factor receptor binding Hs molecular function 617 0.0
calcium ion binding Hs molecular function 617 0.0
protein binding Hs molecular function 617 0.0
nucleus Hs cellular component 617 0.0
nucleoplasm Hs cellular component 601 0.0
cytoplasm Hs cellular component 617 0.0
cytosol Hs cellular component 617 0.0
plasma membrane Hs cellular component 617 0.0
focal adhesion Hs cellular component 617 0.0
zinc ion binding Hs molecular function 601 0.0
membrane Hs cellular component 617 0.0
flotillin complex Hs cellular component 617 0.0
transferase activity Hs molecular function 617 0.0
SH3 domain binding Hs molecular function 617 0.0
protein kinase binding Hs molecular function 617 0.0
axon Hs cellular component 617 0.0
growth cone Hs cellular component 617 0.0
receptor tyrosine kinase binding Hs molecular function 617 0.0
phosphatidylinositol 3-kinase regulatory subunit binding Hs molecular function 617 0.0
mast cell granule Hs cellular component 617 0.0
membrane raft Hs cellular component 617 0.0
cadherin binding Hs molecular function 617 0.0
metal ion binding Hs molecular function 617 0.0
ephrin receptor binding Hs molecular function 617 0.0
perinuclear region of cytoplasm Hs cellular component 617 0.0
ubiquitin protein ligase activity Hs molecular function 617 0.0
extracellular exosome Hs cellular component 390 1.13e-127
protein tyrosine kinase binding Hs molecular function 617 0.0

GO (InterProScan)

7 results

GO Term Analysis Type e-value
phosphotyrosine residue binding ProSiteProfiles molecular function 81.943
ubiquitin-protein transferase activity PANTHER molecular function 1.0E-236
signal transducer activity Gene3D molecular function 1.5E-53
calcium ion binding Pfam molecular function 4.2E-39
nucleus Pfam cellular component 1.6E-52
cell surface receptor signaling pathway Gene3D biological process 1.5E-53
regulation of signaling PANTHER biological process 1.0E-236

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