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GENE CARD

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Gene Card

Best human hits

EXO1; FEN1; GEN1

Unique Gene ID

Cirobu.g00002010

Gene Model ID

KH2012:KH.C11.197

Location

KhC11:360038..362803

External Database Gene Card

External database links

2 results

Collections

Gateway full ORF

2 results

cien92545

Plate: VES84_F19

cien206915

Plate: VES102_F10

Gene collection 1 (N. Satoh)

1 result

cieg002n24

Plate: R1CiGC15d08

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term Analysis Definition
XPG-I_dom SMART XPG-I domain
Exo1 PANTHER Exonuclease 1
XPG_DNA_repair_N SMART XPG N-terminal
XPG-I_dom Pfam XPG-I domain
HhH2 SMART Helix-hairpin-helix motif, class 2
XPG_CS ProSitePatterns XPG conserved site
XPG/Rad2 PANTHER XPG/Rad2 endonuclease
XPG_DNA_repair_N Pfam XPG N-terminal
EXO1_H3TH CDD Exonuclease-1, H3TH domain
PIN-like_dom_sf SUPERFAMILY PIN-like domain superfamily
5-3_exonuclease_C_sf SUPERFAMILY 5'-3' exonuclease, C-terminal domain superfamily
XPG/Rad2 PRINTS XPG/Rad2 endonuclease

GOSlim

29 results

GO Term Annotation Origin Type
magnesium ion binding Blast molecular function
immune system process Orthology biological process
DNA binding Orthology molecular function
chromatin binding Orthology molecular function
double-stranded DNA binding Blast molecular function
catalytic activity Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
nucleolus Blast cellular component
mitochondrion Blast cellular component
centrosome Blast cellular component
plasma membrane Orthology cellular component
DNA replication Orthology biological process
DNA repair Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
membrane Blast cellular component
nuclear body Orthology cellular component
hydrolase activity Orthology molecular function
macromolecular complex Blast cellular component
metal ion binding Orthology molecular function
extracellular exosome Blast cellular component
DNA metabolic process Orthology biological process
RNA metabolic process Orthology biological process
system development Orthology biological process
immune response Orthology biological process
reproductive process Orthology biological process
intracellular non-membrane-bounded organelle Blast cellular component
nuclear lumen Blast cellular component

GO (Orthology)

33 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
DNA synthesis involved in DNA repair Hs biological process
strand displacement Hs biological process
immune system process Hs biological process
DNA binding Hs molecular function
chromatin binding Hs molecular function
catalytic activity Hs molecular function
nuclease activity Hs molecular function
endonuclease activity Hs molecular function
RNA-DNA hybrid ribonuclease activity Hs molecular function
exonuclease activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
plasma membrane Hs cellular component
DNA replication Hs biological process
DNA repair Hs biological process
mismatch repair Hs biological process
DNA recombination Hs biological process
cellular response to DNA damage stimulus Hs biological process
5'-3' exonuclease activity Hs molecular function
somatic hypermutation of immunoglobulin genes Hs biological process
nuclear body Hs cellular component
hydrolase activity Hs molecular function
hydrolase activity, acting on ester bonds Hs molecular function
5'-3' exodeoxyribonuclease activity Hs molecular function
single-stranded DNA 5'-3' exodeoxyribonuclease activity Hs molecular function
isotype switching Hs biological process
metal ion binding Hs molecular function
flap endonuclease activity Hs molecular function
meiotic cell cycle Hs biological process
double-stranded DNA 5'-3' exodeoxyribonuclease activity Hs molecular function
nucleic acid phosphodiester bond hydrolysis Hs biological process
RNA phosphodiester bond hydrolysis, endonucleolytic Hs biological process

GO (Blast)

34 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
magnesium ion binding Hs molecular function 88.2 1.38e-18
nuclear chromosome, telomeric region Hs cellular component 88.2 1.38e-18
DNA binding Hs molecular function 419 4.49e-135
chromatin binding Hs molecular function 419 4.49e-135
damaged DNA binding Hs molecular function 88.2 1.38e-18
double-stranded DNA binding Hs molecular function 88.2 1.38e-18
catalytic activity Hs molecular function 419 4.49e-135
nuclease activity Hs molecular function 419 4.49e-135
endonuclease activity Hs molecular function 419 4.49e-135
endodeoxyribonuclease activity Hs molecular function 68.6 9.16e-12
RNA-DNA hybrid ribonuclease activity Hs molecular function 419 4.49e-135
exonuclease activity Hs molecular function 419 4.49e-135
protein binding Hs molecular function 419 4.49e-135
nucleus Hs cellular component 419 4.49e-135
nucleoplasm Hs cellular component 419 4.49e-135
nucleolus Hs cellular component 88.2 1.38e-18
mitochondrion Hs cellular component 88.2 1.38e-18
centrosome Hs cellular component 68.6 9.16e-12
plasma membrane Hs cellular component 419 4.49e-135
double-stranded DNA exodeoxyribonuclease activity Hs molecular function 88.2 1.38e-18
5'-3' exonuclease activity Hs molecular function 419 4.49e-135
crossover junction endodeoxyribonuclease activity Hs molecular function 68.6 9.16e-12
membrane Hs cellular component 88.2 1.38e-18
nuclear body Hs cellular component 419 4.49e-135
hydrolase activity Hs molecular function 419 4.49e-135
hydrolase activity, acting on ester bonds Hs molecular function 419 4.49e-135
5'-flap endonuclease activity Hs molecular function 88.2 1.38e-18
macromolecular complex Hs cellular component 88.2 1.38e-18
5'-3' exodeoxyribonuclease activity Hs molecular function 419 4.49e-135
single-stranded DNA 5'-3' exodeoxyribonuclease activity Hs molecular function 419 4.49e-135
metal ion binding Hs molecular function 419 4.49e-135
flap endonuclease activity Hs molecular function 419 4.49e-135
double-stranded DNA 5'-3' exodeoxyribonuclease activity Hs molecular function 419 4.49e-135
extracellular exosome Hs cellular component 68.6 9.16e-12

GO (InterProScan)

6 results

GO Term Analysis Type e-value
DNA binding CDD molecular function 4.92388E-26
catalytic activity SMART molecular function 1.2E-7
nuclease activity PANTHER molecular function 2.6E-146
DNA repair PANTHER biological process 2.6E-146
hydrolase activity, acting on ester bonds ProSitePatterns molecular function
5'-3' exodeoxyribonuclease activity PANTHER molecular function 2.6E-146