Gene Card
Best human hits
EXO1; FEN1; GEN1
Unique Gene ID
Cirobu.g00002010
Gene Model ID
KH2012:KH.C11.197
Location
KhC11:360038..362803
Transcript Models and Sequences
KH2012:KH.C11.197.v1.A.nonSL2-1
KH2012:KH.C11.197.v1.A.nonSL3-1
KH2012:KH.C11.197.v1.A.SL4-1
KH2012:KH.C11.197.v1.R.ND1-1
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000021072 |
NCBI Reference Sequence | XM_002130178.2 |
cien92545
Plate: VES84_F19
cien206915
Plate: VES102_F10
cieg002n24
Plate: R1CiGC15d08
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
XPG-I_dom | SMART | XPG-I domain |
Exo1 | PANTHER | Exonuclease 1 |
XPG_DNA_repair_N | SMART | XPG N-terminal |
XPG-I_dom | Pfam | XPG-I domain |
HhH2 | SMART | Helix-hairpin-helix motif, class 2 |
XPG_CS | ProSitePatterns | XPG conserved site |
XPG/Rad2 | PANTHER | XPG/Rad2 endonuclease |
XPG_DNA_repair_N | Pfam | XPG N-terminal |
EXO1_H3TH | CDD | Exonuclease-1, H3TH domain |
PIN-like_dom_sf | SUPERFAMILY | PIN-like domain superfamily |
5-3_exonuclease_C_sf | SUPERFAMILY | 5'-3' exonuclease, C-terminal domain superfamily |
XPG/Rad2 | PRINTS | XPG/Rad2 endonuclease |
GO Term | Annotation Origin | Type |
---|---|---|
magnesium ion binding | Blast | molecular function |
immune system process | Orthology | biological process |
DNA binding | Orthology | molecular function |
chromatin binding | Orthology | molecular function |
double-stranded DNA binding | Blast | molecular function |
catalytic activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
nucleolus | Blast | cellular component |
mitochondrion | Blast | cellular component |
centrosome | Blast | cellular component |
plasma membrane | Orthology | cellular component |
DNA replication | Orthology | biological process |
DNA repair | Orthology | biological process |
cellular response to DNA damage stimulus | Orthology | biological process |
membrane | Blast | cellular component |
nuclear body | Orthology | cellular component |
hydrolase activity | Orthology | molecular function |
macromolecular complex | Blast | cellular component |
metal ion binding | Orthology | molecular function |
extracellular exosome | Blast | cellular component |
DNA metabolic process | Orthology | biological process |
RNA metabolic process | Orthology | biological process |
system development | Orthology | biological process |
immune response | Orthology | biological process |
reproductive process | Orthology | biological process |
intracellular non-membrane-bounded organelle | Blast | cellular component |
nuclear lumen | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
DNA synthesis involved in DNA repair | Hs | biological process |
strand displacement | Hs | biological process |
immune system process | Hs | biological process |
DNA binding | Hs | molecular function |
chromatin binding | Hs | molecular function |
catalytic activity | Hs | molecular function |
nuclease activity | Hs | molecular function |
endonuclease activity | Hs | molecular function |
RNA-DNA hybrid ribonuclease activity | Hs | molecular function |
exonuclease activity | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
plasma membrane | Hs | cellular component |
DNA replication | Hs | biological process |
DNA repair | Hs | biological process |
mismatch repair | Hs | biological process |
DNA recombination | Hs | biological process |
cellular response to DNA damage stimulus | Hs | biological process |
5'-3' exonuclease activity | Hs | molecular function |
somatic hypermutation of immunoglobulin genes | Hs | biological process |
nuclear body | Hs | cellular component |
hydrolase activity | Hs | molecular function |
hydrolase activity, acting on ester bonds | Hs | molecular function |
5'-3' exodeoxyribonuclease activity | Hs | molecular function |
single-stranded DNA 5'-3' exodeoxyribonuclease activity | Hs | molecular function |
isotype switching | Hs | biological process |
metal ion binding | Hs | molecular function |
flap endonuclease activity | Hs | molecular function |
meiotic cell cycle | Hs | biological process |
double-stranded DNA 5'-3' exodeoxyribonuclease activity | Hs | molecular function |
nucleic acid phosphodiester bond hydrolysis | Hs | biological process |
RNA phosphodiester bond hydrolysis, endonucleolytic | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
magnesium ion binding | Hs | molecular function | 88.2 | 1.38e-18 |
nuclear chromosome, telomeric region | Hs | cellular component | 88.2 | 1.38e-18 |
DNA binding | Hs | molecular function | 419 | 4.49e-135 |
chromatin binding | Hs | molecular function | 419 | 4.49e-135 |
damaged DNA binding | Hs | molecular function | 88.2 | 1.38e-18 |
double-stranded DNA binding | Hs | molecular function | 88.2 | 1.38e-18 |
catalytic activity | Hs | molecular function | 419 | 4.49e-135 |
nuclease activity | Hs | molecular function | 419 | 4.49e-135 |
endonuclease activity | Hs | molecular function | 419 | 4.49e-135 |
endodeoxyribonuclease activity | Hs | molecular function | 68.6 | 9.16e-12 |
RNA-DNA hybrid ribonuclease activity | Hs | molecular function | 419 | 4.49e-135 |
exonuclease activity | Hs | molecular function | 419 | 4.49e-135 |
protein binding | Hs | molecular function | 419 | 4.49e-135 |
nucleus | Hs | cellular component | 419 | 4.49e-135 |
nucleoplasm | Hs | cellular component | 419 | 4.49e-135 |
nucleolus | Hs | cellular component | 88.2 | 1.38e-18 |
mitochondrion | Hs | cellular component | 88.2 | 1.38e-18 |
centrosome | Hs | cellular component | 68.6 | 9.16e-12 |
plasma membrane | Hs | cellular component | 419 | 4.49e-135 |
double-stranded DNA exodeoxyribonuclease activity | Hs | molecular function | 88.2 | 1.38e-18 |
5'-3' exonuclease activity | Hs | molecular function | 419 | 4.49e-135 |
crossover junction endodeoxyribonuclease activity | Hs | molecular function | 68.6 | 9.16e-12 |
membrane | Hs | cellular component | 88.2 | 1.38e-18 |
nuclear body | Hs | cellular component | 419 | 4.49e-135 |
hydrolase activity | Hs | molecular function | 419 | 4.49e-135 |
hydrolase activity, acting on ester bonds | Hs | molecular function | 419 | 4.49e-135 |
5'-flap endonuclease activity | Hs | molecular function | 88.2 | 1.38e-18 |
macromolecular complex | Hs | cellular component | 88.2 | 1.38e-18 |
5'-3' exodeoxyribonuclease activity | Hs | molecular function | 419 | 4.49e-135 |
single-stranded DNA 5'-3' exodeoxyribonuclease activity | Hs | molecular function | 419 | 4.49e-135 |
metal ion binding | Hs | molecular function | 419 | 4.49e-135 |
flap endonuclease activity | Hs | molecular function | 419 | 4.49e-135 |
double-stranded DNA 5'-3' exodeoxyribonuclease activity | Hs | molecular function | 419 | 4.49e-135 |
extracellular exosome | Hs | cellular component | 68.6 | 9.16e-12 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
DNA binding | CDD | molecular function | 4.92388E-26 |
catalytic activity | SMART | molecular function | 1.2E-7 |
nuclease activity | PANTHER | molecular function | 2.6E-146 |
DNA repair | PANTHER | biological process | 2.6E-146 |
hydrolase activity, acting on ester bonds | ProSitePatterns | molecular function | |
5'-3' exodeoxyribonuclease activity | PANTHER | molecular function | 2.6E-146 |