Database	Gene ID
ENSEMBL	ENSCING00000023187
NCBI Reference Sequence	XM_002130640.4
NCBI Reference Sequence	XM_002130706.4
NCBI Reference Sequence	XM_002130726.4
NCBI Reference Sequence	XM_002130745.4

IPR Term	Analysis	Definition
CH-domain	ProSiteProfiles	Calponin homology domain
EF_hand_dom	ProSiteProfiles	EF-hand domain
EF_hand_dom	CDD	EF-hand domain
CH_dom_sf	Gene3D	CH domain superfamily
CH-domain	CDD	Calponin homology domain
EF-hand-dom_pair	SUPERFAMILY	EF-hand domain pair
Spectrin/alpha-actinin	SMART	Spectrin/alpha-actinin
CH-domain	SMART	Calponin homology domain
Actinin_actin-bd_CS	ProSitePatterns	Actinin-type actin-binding domain, conserved site
CH_dom_sf	SUPERFAMILY	CH domain superfamily
EF-hand_Ca_insen	Pfam	EF-hand, Ca insensitive
EF_hand_dom	SMART	EF-hand domain
CH-domain	Pfam	Calponin homology domain
Spectrin_repeat	Pfam	Spectrin repeat

GO Term	Annotation Origin	Type
RNA polymerase II regulatory region sequence-specific DNA binding	Orthology	molecular function
response to hypoxia	Orthology	biological process
nucleoside binding	Orthology	molecular function
RNA binding	Orthology	molecular function
actin binding	Orthology	molecular function
integrin binding	Orthology	molecular function
calcium ion binding	Orthology	molecular function
protein binding	Orthology	molecular function
extracellular region	Orthology	cellular component
extracellular space	Orthology	cellular component
intracellular	Orthology	cellular component
nucleus	Orthology	cellular component
cytoplasm	Orthology	cellular component
cytosol	Orthology	cellular component
cytoskeleton	Orthology	cellular component
plasma membrane	Orthology	cellular component
brush border	Orthology	cellular component
focal adhesion	Orthology	cellular component
cell adhesion	Orthology	biological process
cytoskeletal protein binding	Orthology	molecular function
protein transport	Orthology	biological process
nuclear body	Orthology	cellular component
cell junction	Orthology	cellular component
macromolecular complex	Orthology	cellular component
identical protein binding	Orthology	molecular function
protein homodimerization activity	Orthology	molecular function
regulation of apoptotic process	Orthology	biological process
neuron projection	Orthology	cellular component
metal ion binding	Orthology	molecular function
protein dimerization activity	Orthology	molecular function
protein N-terminus binding	Orthology	molecular function
perinuclear region of cytoplasm	Orthology	cellular component
actin filament binding	Orthology	molecular function
extracellular exosome	Orthology	cellular component
regulation of nucleic acid-templated transcription	Orthology	biological process
membrane	Orthology	cellular component
cell projection	Orthology	cellular component
intracellular signal transduction	Orthology	biological process
protein phosphorylation	Orthology	biological process
cytoskeletal part	Orthology	cellular component
membrane organization	Orthology	biological process
organelle organization	Orthology	biological process
enzyme binding	Orthology	molecular function
molecular function regulator	Orthology	molecular function
anion binding	Orthology	molecular function
structural molecule activity	Orthology	molecular function
cytoplasmic part	Orthology	cellular component
organelle part	Orthology	cellular component
intracellular non-membrane-bounded organelle	Orthology	cellular component
intracellular transport	Orthology	biological process
plasma membrane region	Orthology	cellular component
cell migration	Orthology	biological process
transcription coactivator activity	Orthology	molecular function
cell periphery	Orthology	cellular component
intracellular organelle part	Orthology	cellular component
cytoplasmic vesicle	Orthology	cellular component
endomembrane system	Orthology	cellular component
intracellular organelle lumen	Orthology	cellular component
chromatin binding	Orthology	molecular function
DNA binding	Orthology	molecular function
receptor binding	Orthology	molecular function
transcription factor binding	Orthology	molecular function
signal transduction	Orthology	biological process
postsynapse	Orthology	cellular component
metal ion transport	Orthology	biological process
monovalent inorganic cation transport	Orthology	biological process
cell development	Orthology	biological process
protein homooligomerization	Orthology	biological process
heart development	Orthology	biological process
protein localization to membrane	Orthology	biological process
cell morphogenesis involved in differentiation	Orthology	biological process
cellular protein localization	Orthology	biological process
transmembrane transport	Orthology	biological process
cation transport	Orthology	biological process
cell leading edge	Orthology	cellular component
adherens junction	Orthology	cellular component
response to stimulus	Orthology	biological process
anatomical structure formation involved in morphogenesis	Orthology	biological process
immune system process	Orthology	biological process
animal organ development	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
MAPK cascade	Hs	biological process
RNA polymerase II regulatory region sequence-specific DNA binding	Hs	molecular function
response to hypoxia	Hs	biological process
stress fiber	Hs	cellular component
nucleoside binding	Hs	molecular function
platelet degranulation	Hs	biological process
RNA binding	Hs	molecular function
actin binding	Hs	molecular function
Ras guanyl-nucleotide exchange factor activity	Hs	molecular function
integrin binding	Hs	molecular function
calcium ion binding	Hs	molecular function
protein binding	Hs	molecular function
phosphatidylinositol-4,5-bisphosphate binding	Hs	molecular function
extracellular region	Hs	cellular component
extracellular space	Hs	cellular component
intracellular	Hs	cellular component
nucleus	Hs	cellular component
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
cytoskeleton	Hs	cellular component
actin filament	Hs	cellular component
plasma membrane	Hs	cellular component
brush border	Hs	cellular component
cell-cell junction	Hs	cellular component
focal adhesion	Hs	cellular component
muscle contraction	Hs	biological process
cell adhesion	Hs	biological process
cytoskeletal protein binding	Hs	molecular function
structural constituent of muscle	Hs	molecular function
protein transport	Hs	biological process
actin cytoskeleton	Hs	cellular component
nuclear body	Hs	cellular component
protein domain specific binding	Hs	molecular function
sarcomere	Hs	cellular component
Z disc	Hs	cellular component
vesicle transport along actin filament	Hs	biological process
cell junction	Hs	cellular component
filopodium	Hs	cellular component
LIM domain binding	Hs	molecular function
positive regulation of cell migration	Hs	biological process
ligand-dependent nuclear receptor transcription coactivator activity	Hs	molecular function
thyroid hormone receptor coactivator activity	Hs	molecular function
intracellular ribonucleoprotein complex	Hs	cellular component
cortical cytoskeleton	Hs	cellular component
cortical actin cytoskeleton	Hs	cellular component
platelet alpha granule lumen	Hs	cellular component
pseudopodium	Hs	cellular component
titin binding	Hs	molecular function
chromatin DNA binding	Hs	molecular function
macromolecular complex	Hs	cellular component
nuclear hormone receptor binding	Hs	molecular function
peroxisome proliferator activated receptor signaling pathway	Hs	biological process
regulation of membrane potential	Hs	biological process
identical protein binding	Hs	molecular function
protein homodimerization activity	Hs	molecular function
retinoic acid receptor binding	Hs	molecular function
regulation of apoptotic process	Hs	biological process
neuron projection	Hs	cellular component
dendritic spine	Hs	cellular component
negative regulation of potassium ion transport	Hs	biological process
ion channel binding	Hs	molecular function
sarcomere organization	Hs	biological process
metal ion binding	Hs	molecular function
protein dimerization activity	Hs	molecular function
protein N-terminus binding	Hs	molecular function
focal adhesion assembly	Hs	biological process
retinoic acid receptor signaling pathway	Hs	biological process
perinuclear region of cytoplasm	Hs	cellular component
actin filament binding	Hs	molecular function
actin filament bundle assembly	Hs	biological process
protein homotetramerization	Hs	biological process
FATZ binding	Hs	molecular function
cardiac muscle cell development	Hs	biological process
extracellular exosome	Hs	cellular component
titin Z domain binding	Hs	molecular function
bicellular tight junction assembly	Hs	biological process
protein localization to plasma membrane	Hs	biological process
negative regulation of substrate adhesion-dependent cell spreading	Hs	biological process
regulation of nucleic acid-templated transcription	Hs	biological process
negative regulation of protein localization to cell surface	Hs	biological process
positive regulation of cation channel activity	Hs	biological process
ruffle	Hs	cellular component
double-stranded RNA binding	Hs	molecular function
fascia adherens	Hs	cellular component
actin filament organization	Hs	biological process
skeletal muscle atrophy	Hs	biological process
membrane	Hs	cellular component
vinculin binding	Hs	molecular function
platelet formation	Hs	biological process
cell projection	Hs	cellular component
positive regulation of skeletal muscle fiber development	Hs	biological process
actin filament network formation	Hs	biological process
actin crosslink formation	Hs	biological process
bone morphogenesis	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
RNA polymerase II regulatory region sequence-specific DNA binding	Hs	molecular function	1209	0.0
stress fiber	Hs	cellular component	1209	0.0
nucleoside binding	Hs	molecular function	1209	0.0
RNA binding	Hs	molecular function	1209	0.0
actin binding	Hs	molecular function	1256	0.0
Ras guanyl-nucleotide exchange factor activity	Hs	molecular function	1256	0.0
integrin binding	Hs	molecular function	1256	0.0
calcium ion binding	Hs	molecular function	1256	0.0
protein binding	Hs	molecular function	1256	0.0
phosphatidylinositol-4,5-bisphosphate binding	Hs	molecular function	1256	0.0
extracellular region	Hs	cellular component	1256	0.0
extracellular space	Hs	cellular component	1209	0.0
intracellular	Hs	cellular component	1209	0.0
nucleus	Hs	cellular component	1209	0.0
cytoplasm	Hs	cellular component	1256	0.0
cytosol	Hs	cellular component	1256	0.0
cytoskeleton	Hs	cellular component	1256	0.0
actin filament	Hs	cellular component	1256	0.0
plasma membrane	Hs	cellular component	1256	0.0
brush border	Hs	cellular component	1209	0.0
cell-cell junction	Hs	cellular component	1209	0.0
focal adhesion	Hs	cellular component	1256	0.0
cytoskeletal protein binding	Hs	molecular function	1256	0.0
structural constituent of muscle	Hs	molecular function	1256	0.0
actin cytoskeleton	Hs	cellular component	1209	0.0
nuclear body	Hs	cellular component	1209	0.0
protein domain specific binding	Hs	molecular function	1256	0.0
sarcomere	Hs	cellular component	1256	0.0
Z disc	Hs	cellular component	1256	0.0
cell junction	Hs	cellular component	1209	0.0
filopodium	Hs	cellular component	1256	0.0
LIM domain binding	Hs	molecular function	1256	0.0
ligand-dependent nuclear receptor transcription coactivator activity	Hs	molecular function	1256	0.0
thyroid hormone receptor coactivator activity	Hs	molecular function	1256	0.0
intracellular ribonucleoprotein complex	Hs	cellular component	1209	0.0
cortical cytoskeleton	Hs	cellular component	1209	0.0
cortical actin cytoskeleton	Hs	cellular component	1256	0.0
platelet alpha granule lumen	Hs	cellular component	1256	0.0
pseudopodium	Hs	cellular component	1256	0.0
titin binding	Hs	molecular function	1256	0.0
chromatin DNA binding	Hs	molecular function	1209	0.0
macromolecular complex	Hs	cellular component	1209	0.0
nuclear hormone receptor binding	Hs	molecular function	1209	0.0
identical protein binding	Hs	molecular function	1256	0.0
protein homodimerization activity	Hs	molecular function	1256	0.0
retinoic acid receptor binding	Hs	molecular function	1209	0.0
neuron projection	Hs	cellular component	1209	0.0
dendritic spine	Hs	cellular component	1256	0.0
ion channel binding	Hs	molecular function	1256	0.0
metal ion binding	Hs	molecular function	1256	0.0
protein dimerization activity	Hs	molecular function	1256	0.0
protein N-terminus binding	Hs	molecular function	1209	0.0
perinuclear region of cytoplasm	Hs	cellular component	1209	0.0
actin filament binding	Hs	molecular function	1256	0.0
FATZ binding	Hs	molecular function	1256	0.0
extracellular exosome	Hs	cellular component	1256	0.0
titin Z domain binding	Hs	molecular function	1256	0.0

GO Term	Analysis	Type	e-value
calcium ion binding	CDD	molecular function	2.35536E-9
protein binding	Pfam	molecular function	5.0E-28