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Gene Card

Best human hits

REL; RELA; RELB

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00002055

Gene Model ID

KH2012:KH.C11.238

Location

KhC11:3650557..3658587

Transcript Models and Sequences

  KH2012:KH.C11.238.v1.A.SL1-2
KH2012:KH.C11.238.v1.A.SL3-2
KH2012:KH.C11.238.v2.A.SL1-1
KH2012:KH.C11.238.v2.A.SL3-1
KH2012:KH.C11.238.v3.A.SL2-2

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000022223
NCBI Reference Sequence NM_001033841.1
Collections

Gateway full ORF

1 result

cien185437

Plate: VES98_B22

Gene collection 1 (N. Satoh)

4 results

cicl009e23

Plate: R1CiGC09m04

cieg022h11

Plate: R1CiGC19a03

cilv034c09

Plate: R1CiGC27j10

cigd044n09

Plate: R1CiGC41n01

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term Analysis Definition
IPT_dom SMART IPT domain
NFkB/Dor PANTHER NF-kappa-B/Dorsal
RHD_DNA_bind_dom_sf Gene3D Rel homology domain (RHD), DNA-binding domain superfamily
RHD_CS ProSitePatterns Rel homology domain, conserved site
RHD_dimer Pfam Rel homology dimerisation domain
Ig_E-set SUPERFAMILY Immunoglobulin E-set
IPT_NFkappaB CDD NFkappaB IPT domain
NFkB/Dor PRINTS NF-kappa-B/Dorsal
p53-like_TF_DNA-bd SUPERFAMILY p53-like transcription factor, DNA-binding
RHD_DNA_bind_dom Pfam Rel homology domain (RHD), DNA-binding domain
RHD_DNA_bind_dom ProSiteProfiles Rel homology domain (RHD), DNA-binding domain
Ig-like_fold Gene3D Immunoglobulin-like fold

GOSlim

70 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
RNA polymerase II regulatory region sequence-specific DNA binding Orthology molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding Orthology molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
DNA binding Orthology molecular function
chromatin binding Orthology molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcription corepressor activity Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
centrosome Orthology cellular component
microtubule organizing center Orthology cellular component
cytosol Orthology cellular component
cytoskeleton Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
transcription from RNA polymerase II promoter Orthology biological process
defense response Orthology biological process
transcription factor binding Orthology molecular function
positive regulation of cell proliferation Orthology biological process
response to bacterium Orthology biological process
response to organic substance Orthology biological process
positive regulation of gene expression Orthology biological process
negative regulation of gene expression Orthology biological process
cytokine-mediated signaling pathway Orthology biological process
enzyme binding Orthology molecular function
protein kinase binding Orthology molecular function
ubiquitin protein ligase binding Orthology molecular function
response to lipopolysaccharide Orthology biological process
macromolecular complex Orthology cellular component
response to cytokine Orthology biological process
identical protein binding Orthology molecular function
protein homodimerization activity Orthology molecular function
negative regulation of apoptotic process Orthology biological process
sequence-specific DNA binding Orthology molecular function
transcription regulatory region DNA binding Orthology molecular function
innate immune response Orthology biological process
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
protein heterodimerization activity Orthology molecular function
protein N-terminus binding Orthology molecular function
intracellular non-membrane-bounded organelle Orthology cellular component
nuclear lumen Orthology cellular component
animal organ development Orthology biological process
intracellular part Orthology cellular component
intracellular signal transduction Orthology biological process
developmental process Orthology biological process
anatomical structure morphogenesis Orthology biological process
immune system process Orthology biological process
cell differentiation Orthology biological process
proteolysis Orthology biological process
response to lipid Orthology biological process
regulation of gene expression Orthology biological process
protein modification by small protein conjugation Orthology biological process
cell surface receptor signaling pathway Orthology biological process
immune response Orthology biological process
protein metabolic process Orthology biological process
anion binding Orthology molecular function
response to oxidative stress Orthology biological process
cytoskeletal protein binding Orthology molecular function
positive regulation of signal transduction Orthology biological process
cellular response to stress Orthology biological process
negative regulation of signal transduction Orthology biological process
cellular response to organic substance Orthology biological process
negative regulation of cell death Orthology biological process
regulation of signal transduction Orthology biological process

GO (Orthology)

114 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
nuclear chromatin Hs cellular component
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function
RNA polymerase II distal enhancer sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
transcription factor activity, RNA polymerase II core promoter sequence-specific Hs molecular function
core promoter binding Hs molecular function
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function
liver development Hs biological process
DNA binding Hs molecular function
chromatin binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function
transcription corepressor activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
transcription factor complex Hs cellular component
cytoplasm Hs cellular component
centrosome Hs cellular component
microtubule organizing center Hs cellular component
cytosol Hs cellular component
cytoskeleton Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
regulation of transcription from RNA polymerase II promoter Hs biological process
transcription from RNA polymerase II promoter Hs biological process
defense response Hs biological process
inflammatory response Hs biological process
cellular defense response Hs biological process
I-kappaB kinase/NF-kappaB signaling Hs biological process
aging Hs biological process
transcription factor binding Hs molecular function
positive regulation of cell proliferation Hs biological process
response to mechanical stimulus Hs biological process
response to bacterium Hs biological process
animal organ morphogenesis Hs biological process
response to organic substance Hs biological process
response to inorganic substance Hs biological process
response to UV-B Hs biological process
positive regulation of gene expression Hs biological process
negative regulation of gene expression Hs biological process
response to organic cyclic compound Hs biological process
viral process Hs biological process
cytokine-mediated signaling pathway Hs biological process
antigen processing and presentation Hs biological process
enzyme binding Hs molecular function
protein kinase binding Hs molecular function
lymphocyte differentiation Hs biological process
membrane protein intracellular domain proteolysis Hs biological process
chromatin DNA binding Hs molecular function
ubiquitin protein ligase binding Hs molecular function
positive regulation of chondrocyte differentiation Hs biological process
positive regulation of type I interferon production Hs biological process
response to lipopolysaccharide Hs biological process
response to progesterone Hs biological process
response to insulin Hs biological process
circadian regulation of gene expression Hs biological process
macromolecular complex Hs cellular component
tumor necrosis factor-mediated signaling pathway Hs biological process
negative regulation of protein sumoylation Hs biological process
I-kappaB/NF-kappaB complex Hs cellular component
activating transcription factor binding Hs molecular function
response to cytokine Hs biological process
NF-kappaB p50/p65 complex Hs cellular component
NIK/NF-kappaB signaling Hs biological process
Fc-epsilon receptor signaling pathway Hs biological process
T-helper 1 type immune response Hs biological process
negative regulation of protein catabolic process Hs biological process
phosphate ion binding Hs molecular function
response to drug Hs biological process
response to hydrogen peroxide Hs biological process
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
actinin binding Hs molecular function
histone deacetylase binding Hs molecular function
myeloid dendritic cell differentiation Hs biological process
negative regulation of apoptotic process Hs biological process
positive regulation of I-kappaB kinase/NF-kappaB signaling Hs biological process
response to amino acid Hs biological process
sequence-specific DNA binding Hs molecular function
regulation of DNA-templated transcription in response to stress Hs biological process
transcription regulatory region DNA binding Hs molecular function
innate immune response Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
negative regulation of insulin receptor signaling pathway Hs biological process
protein heterodimerization activity Hs molecular function
protein N-terminus binding Hs molecular function
rhythmic process Hs biological process
regulation of inflammatory response Hs biological process
T cell receptor signaling pathway Hs biological process
positive regulation of T cell receptor signaling pathway Hs biological process
NF-kappaB binding Hs molecular function
positive regulation of NF-kappaB transcription factor activity Hs biological process
response to cAMP Hs biological process
defense response to virus Hs biological process
cellular response to hydrogen peroxide Hs biological process
repressing transcription factor binding Hs molecular function
interleukin-1-mediated signaling pathway Hs biological process
NF-kappaB complex Hs cellular component
cellular response to lipopolysaccharide Hs biological process
cellular response to interleukin-1 Hs biological process
cellular response to tumor necrosis factor Hs biological process
cellular response to osmotic stress Hs biological process
ankyrin repeat binding Hs molecular function
negative regulation of neuron death Hs biological process
regulation of NIK/NF-kappaB signaling Hs biological process
negative regulation of NIK/NF-kappaB signaling Hs biological process
negative regulation of extrinsic apoptotic signaling pathway Hs biological process

GO (Blast)

46 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nuclear chromatin Hs cellular component 306 1.45e-95
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function 306 1.45e-95
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function 306 1.45e-95
RNA polymerase II distal enhancer sequence-specific DNA binding Hs molecular function 315 2.51e-98
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 315 2.51e-98
transcription factor activity, RNA polymerase II core promoter sequence-specific Hs molecular function 306 1.45e-95
core promoter binding Hs molecular function 287 3.97e-88
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function 306 1.45e-95
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function 306 1.45e-95
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function 315 2.51e-98
DNA binding Hs molecular function 315 2.51e-98
chromatin binding Hs molecular function 315 2.51e-98
transcription factor activity, sequence-specific DNA binding Hs molecular function 315 2.51e-98
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function 306 1.45e-95
transcription corepressor activity Hs molecular function 287 3.97e-88
protein binding Hs molecular function 315 2.51e-98
nucleus Hs cellular component 315 2.51e-98
nucleoplasm Hs cellular component 315 2.51e-98
transcription factor complex Hs cellular component 315 2.51e-98
cytoplasm Hs cellular component 315 2.51e-98
centrosome Hs cellular component 287 3.97e-88
microtubule organizing center Hs cellular component 287 3.97e-88
cytosol Hs cellular component 315 2.51e-98
cytoskeleton Hs cellular component 287 3.97e-88
transcription factor binding Hs molecular function 306 1.45e-95
enzyme binding Hs molecular function 306 1.45e-95
protein kinase binding Hs molecular function 306 1.45e-95
chromatin DNA binding Hs molecular function 306 1.45e-95
ubiquitin protein ligase binding Hs molecular function 306 1.45e-95
macromolecular complex Hs cellular component 287 3.97e-88
I-kappaB/NF-kappaB complex Hs cellular component 315 2.51e-98
activating transcription factor binding Hs molecular function 306 1.45e-95
NF-kappaB p50/p65 complex Hs cellular component 306 1.45e-95
phosphate ion binding Hs molecular function 306 1.45e-95
identical protein binding Hs molecular function 306 1.45e-95
protein homodimerization activity Hs molecular function 306 1.45e-95
actinin binding Hs molecular function 306 1.45e-95
histone deacetylase binding Hs molecular function 306 1.45e-95
sequence-specific DNA binding Hs molecular function 315 2.51e-98
transcription regulatory region DNA binding Hs molecular function 306 1.45e-95
protein heterodimerization activity Hs molecular function 306 1.45e-95
protein N-terminus binding Hs molecular function 306 1.45e-95
NF-kappaB binding Hs molecular function 306 1.45e-95
repressing transcription factor binding Hs molecular function 306 1.45e-95
NF-kappaB complex Hs cellular component 306 1.45e-95
ankyrin repeat binding Hs molecular function 306 1.45e-95

GO (InterProScan)

5 results

GO Term Analysis Type e-value
DNA binding Pfam molecular function 7.8E-67
transcription factor activity, sequence-specific DNA binding PANTHER molecular function 4.2E-138
nucleus PANTHER cellular component 4.2E-138
cytoplasm PANTHER cellular component 4.2E-138
regulation of transcription, DNA-templated PANTHER biological process 4.2E-138

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