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GENE CARD

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Gene Card

Best human hits

RYR1; RYR2; RYR3

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00002156

Gene Model ID

KH2012:KH.C11.332

Location

KhC11:1779424..1842995

Transcript Models and Sequences

  KH2012:KH.C11.332.v1.A.SL1-1
KH2012:KH.C11.332.v1.A.SL2-1

External Database Gene Card

External database links

1 result

Database Gene ID
NCBI Reference Sequence XM_018813888.1
Collections

Gene collection 1 (N. Satoh)

3 results

ciad008k15

Plate: R1CiGC01h14

citb104n14

Plate: R1CiGC47c09

citb063o15

Plate: R1CiGC46g23

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

19 results

IPR Term Analysis Definition
SPRY3_RyR CDD Ryanodine receptor, SPRY domain 3
ConA-like_dom_sf SUPERFAMILY Concanavalin A-like lectin/glucanase domain superfamily
RIH_assoc-dom Pfam RyR/IP3R Homology associated domain
MIR_motif ProSiteProfiles MIR motif
MIR_dom_sf SUPERFAMILY Mir domain superfamily
Ryanrecept_TM4-6 Pfam Ryanodine Receptor TM 4-6
Ion_trans_dom Pfam Ion transport domain
MIR_motif SMART MIR motif
SPRY_dom SMART SPRY domain
SPRY_dom Pfam SPRY domain
Ryanodine_rcpt Pfam Ryanodine receptor Ryr
SPRY1_RyR CDD Ryanodine receptor, SPRY domain 1
EF-hand-dom_pair SUPERFAMILY EF-hand domain pair
B30.2/SPRY ProSiteProfiles B30.2/SPRY domain
Ins145_P3_rcpt Pfam Inositol 1,4,5-trisphosphate/ryanodine receptor
RIH_dom Pfam RIH domain
Ryanodine_recept-rel PANTHER Ryanodine receptor-related
Ryan_recept PRINTS Ryanodine receptor
MIR_motif Pfam MIR motif

GOSlim

55 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
response to hypoxia Orthology biological process
binding Orthology molecular function
calcium ion binding Orthology molecular function
protein binding Orthology molecular function
calmodulin binding Orthology molecular function
ATP binding Orthology molecular function
cell Orthology cellular component
cytoplasm Orthology cellular component
endoplasmic reticulum Orthology cellular component
plasma membrane Orthology cellular component
integral component of plasma membrane Orthology cellular component
ion transport Orthology biological process
multicellular organism development Orthology biological process
membrane Orthology cellular component
integral component of membrane Orthology cellular component
enzyme binding Orthology molecular function
protein kinase binding Orthology molecular function
organelle membrane Orthology cellular component
macromolecular complex Orthology cellular component
identical protein binding Orthology molecular function
intracellular membrane-bounded organelle Orthology cellular component
metal ion binding Orthology molecular function
perinuclear region of cytoplasm Orthology cellular component
transmembrane transport Orthology biological process
extracellular exosome Orthology cellular component
organic cyclic compound binding Orthology molecular function
heart development Orthology biological process
anatomical structure morphogenesis Orthology biological process
metal ion transport Orthology biological process
intracellular signal transduction Orthology biological process
cell periphery Orthology cellular component
cytoplasmic part Orthology cellular component
cellular process Orthology biological process
endoplasmic reticulum membrane Orthology cellular component
bounding membrane of organelle Orthology cellular component
endoplasmic reticulum part Orthology cellular component
organelle part Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
plasma membrane part Orthology cellular component
cell surface receptor signaling pathway Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
cellular response to organic substance Orthology biological process
response to organic substance Orthology biological process
animal organ development Orthology biological process
small molecule binding Orthology molecular function
anion binding Orthology molecular function
cell development Orthology biological process
localization Orthology biological process
protein homooligomerization Orthology biological process
response to stimulus Orthology biological process
cell-cell signaling Orthology biological process
regulation of signaling Orthology biological process
positive regulation of hydrolase activity Orthology biological process
nucleoside-triphosphatase activity Orthology molecular function

GO (Orthology)

83 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
nucleotide binding Hs molecular function
response to hypoxia Hs biological process
protease binding Hs molecular function
regulation of heart rate Hs biological process
embryonic heart tube morphogenesis Hs biological process
outflow tract morphogenesis Hs biological process
ion channel activity Hs molecular function
ryanodine-sensitive calcium-release channel activity Hs molecular function
voltage-gated calcium channel activity Hs molecular function
calcium channel activity Hs molecular function
binding Hs molecular function
calcium ion binding Hs molecular function
detection of calcium ion Hs biological process
protein binding Hs molecular function
calmodulin binding Hs molecular function
ATP binding Hs molecular function
cell Hs cellular component
cytoplasm Hs cellular component
endoplasmic reticulum Hs cellular component
smooth endoplasmic reticulum Hs cellular component
plasma membrane Hs cellular component
integral component of plasma membrane Hs cellular component
cell cortex Hs cellular component
ion transport Hs biological process
calcium ion transport Hs biological process
cellular calcium ion homeostasis Hs biological process
muscle contraction Hs biological process
multicellular organism development Hs biological process
positive regulation of heart rate Hs biological process
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion Hs biological process
regulation of cardiac muscle contraction by calcium ion signaling Hs biological process
junctional sarcoplasmic reticulum membrane Hs cellular component
terminal cisterna Hs cellular component
calcium-release channel activity Hs molecular function
membrane Hs cellular component
integral component of membrane Hs cellular component
sarcoplasmic reticulum Hs cellular component
calcium-mediated signaling Hs biological process
enzyme binding Hs molecular function
protein kinase binding Hs molecular function
sarcomere Hs cellular component
Z disc Hs cellular component
junctional membrane complex Hs cellular component
T-tubule Hs cellular component
BMP signaling pathway Hs biological process
response to caffeine Hs biological process
organelle membrane Hs cellular component
integral component of organelle membrane Hs cellular component
I band Hs cellular component
macromolecular complex Hs cellular component
sarcoplasmic reticulum membrane Hs cellular component
ion transmembrane transport Hs biological process
protein kinase A catalytic subunit binding Hs molecular function
protein kinase A regulatory subunit binding Hs molecular function
calcium channel complex Hs cellular component
identical protein binding Hs molecular function
intracellular membrane-bounded organelle Hs cellular component
skin development Hs biological process
protein self-association Hs molecular function
suramin binding Hs molecular function
ion channel binding Hs molecular function
metal ion binding Hs molecular function
perinuclear region of cytoplasm Hs cellular component
skeletal muscle fiber development Hs biological process
calcium-induced calcium release activity Hs molecular function
release of sequestered calcium ion into cytosol Hs biological process
positive regulation of sequestering of calcium ion Hs biological process
protein homotetramerization Hs biological process
regulation of cytosolic calcium ion concentration Hs biological process
negative regulation of cytosolic calcium ion concentration Hs biological process
response to redox state Hs biological process
transmembrane transport Hs biological process
regulation of cardiac muscle contraction Hs biological process
cardiac muscle contraction Hs biological process
canonical Wnt signaling pathway Hs biological process
extracellular exosome Hs cellular component
calcium ion transmembrane transport Hs biological process
cellular response to calcium ion Hs biological process
organic cyclic compound binding Hs molecular function
regulation of atrial cardiac muscle cell action potential Hs biological process
positive regulation of calcium-transporting ATPase activity Hs biological process
regulation of cardiac conduction Hs biological process
ryanodine receptor complex Hs cellular component

GO (Blast)

49 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 2305 0.0
protease binding Hs molecular function 2305 0.0
ion channel activity Hs molecular function 3336 0.0
ryanodine-sensitive calcium-release channel activity Hs molecular function 3336 0.0
voltage-gated calcium channel activity Hs molecular function 2305 0.0
calcium channel activity Hs molecular function 3336 0.0
binding Hs molecular function 3336 0.0
calcium ion binding Hs molecular function 3336 0.0
protein binding Hs molecular function 3336 0.0
calmodulin binding Hs molecular function 3336 0.0
ATP binding Hs molecular function 2305 0.0
cell Hs cellular component 3336 0.0
cytoplasm Hs cellular component 2305 0.0
endoplasmic reticulum Hs cellular component 3336 0.0
smooth endoplasmic reticulum Hs cellular component 2860 0.0
plasma membrane Hs cellular component 3336 0.0
integral component of plasma membrane Hs cellular component 2305 0.0
cell cortex Hs cellular component 2305 0.0
junctional sarcoplasmic reticulum membrane Hs cellular component 2860 0.0
terminal cisterna Hs cellular component 2305 0.0
calcium-release channel activity Hs molecular function 3336 0.0
membrane Hs cellular component 3336 0.0
integral component of membrane Hs cellular component 3336 0.0
sarcoplasmic reticulum Hs cellular component 3336 0.0
enzyme binding Hs molecular function 2860 0.0
protein kinase binding Hs molecular function 2860 0.0
sarcomere Hs cellular component 2860 0.0
Z disc Hs cellular component 2860 0.0
junctional membrane complex Hs cellular component 2305 0.0
T-tubule Hs cellular component 2305 0.0
organelle membrane Hs cellular component 3336 0.0
integral component of organelle membrane Hs cellular component 2305 0.0
I band Hs cellular component 2305 0.0
macromolecular complex Hs cellular component 2860 0.0
sarcoplasmic reticulum membrane Hs cellular component 3336 0.0
protein kinase A catalytic subunit binding Hs molecular function 2860 0.0
protein kinase A regulatory subunit binding Hs molecular function 2860 0.0
calcium channel complex Hs cellular component 2860 0.0
identical protein binding Hs molecular function 2860 0.0
intracellular membrane-bounded organelle Hs cellular component 3336 0.0
protein self-association Hs molecular function 2860 0.0
suramin binding Hs molecular function 2860 0.0
ion channel binding Hs molecular function 2860 0.0
metal ion binding Hs molecular function 2305 0.0
perinuclear region of cytoplasm Hs cellular component 3336 0.0
calcium-induced calcium release activity Hs molecular function 3336 0.0
extracellular exosome Hs cellular component 2860 0.0
organic cyclic compound binding Hs molecular function 2860 0.0
ryanodine receptor complex Hs cellular component 2305 0.0

GO (InterProScan)

8 results

GO Term Analysis Type e-value
ion channel activity Pfam molecular function 6.2E-16
calcium channel activity Pfam molecular function 3.5E-69
protein binding SMART molecular function 1.4E-30
ion transport Pfam biological process 6.2E-16
cellular calcium ion homeostasis Pfam biological process 4.4E-48
membrane Pfam cellular component 3.5E-69
transmembrane transport Pfam biological process 6.2E-16
calcium ion transmembrane transport Pfam biological process 3.5E-69

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