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GENE CARD

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Gene Card

Best human hits

DNA2; IGHMBP2; UPF1

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00002746

Gene Model ID

KH2012:KH.C12.212

Location

KhC12:3685561..3696935

Transcript Models and Sequences

  KH2012:KH.C12.212.v1.A.SL1-1

External Database Gene Card

External database links

3 results

Database Gene ID
ENSEMBL ENSCING00000005560
ENSEMBL ENSCING00000023751
NCBI Reference Sequence XM_018814350.1
Collections

Gene collection 1 (N. Satoh)

3 results

citb012b11

Plate: R1CiGC30g18

cieg003e07

Plate: R1CiGC15h12

cicl005n05

Plate: R1CiGC08l12

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

3 results

IPR Term Analysis Definition
Dna2 PANTHER Dna2
DNA_replication_fac_Dna2_N Pfam DNA replication factor Dna2, N-terminal
P-loop_NTPase SUPERFAMILY P-loop containing nucleoside triphosphate hydrolase

GOSlim

41 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
nucleic acid binding Blast molecular function
DNA binding Orthology molecular function
chromatin binding Blast molecular function
RNA binding Blast molecular function
catalytic activity Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Blast cellular component
mitochondrion Orthology cellular component
cytosol Blast cellular component
DNA replication Orthology biological process
DNA repair Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
transcription factor binding Blast molecular function
metabolic process Orthology biological process
zinc ion binding Blast molecular function
membrane Blast cellular component
hydrolase activity Orthology molecular function
axon Blast cellular component
cell projection Blast cellular component
metal ion binding Orthology molecular function
cell cycle Orthology biological process
DNA metabolic process Orthology biological process
organelle organization Orthology biological process
intracellular non-membrane-bounded organelle Orthology cellular component
nuclear lumen Orthology cellular component
nucleoside-triphosphatase activity Orthology molecular function
mitochondrial matrix Orthology cellular component
macromolecular complex Orthology cellular component
RNA catabolic process Orthology biological process
RNA biosynthetic process Orthology biological process
cofactor binding Orthology molecular function
intracellular organelle part Blast cellular component
cytoplasmic part Blast cellular component
cell projection part Blast cellular component
nuclear part Blast cellular component
sequence-specific DNA binding Blast molecular function
macromolecular complex binding Blast molecular function

GO (Orthology)

42 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
DNA replication checkpoint Hs biological process
nucleotide binding Hs molecular function
telomere maintenance Hs biological process
DNA double-strand break processing Hs biological process
DNA synthesis involved in DNA repair Hs biological process
strand displacement Hs biological process
nuclear chromosome, telomeric region Hs cellular component
DNA binding Hs molecular function
DNA helicase activity Hs molecular function
catalytic activity Hs molecular function
helicase activity Hs molecular function
nuclease activity Hs molecular function
endonuclease activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
mitochondrion Hs cellular component
gamma DNA polymerase complex Hs cellular component
DNA replication Hs biological process
mitochondrial DNA replication Hs biological process
DNA repair Hs biological process
base-excision repair Hs biological process
cellular response to DNA damage stimulus Hs biological process
metabolic process Hs biological process
hydrolase activity Hs molecular function
ATPase activity Hs molecular function
site-specific endodeoxyribonuclease activity, specific for altered base Hs molecular function
5'-flap endonuclease activity Hs molecular function
DNA duplex unwinding Hs biological process
DNA replication, Okazaki fragment processing Hs biological process
mitochondrial nucleoid Hs cellular component
DNA replication, removal of RNA primer Hs biological process
5'-3' DNA helicase activity Hs molecular function
single-stranded DNA-dependent ATPase activity Hs molecular function
mitochondrial DNA repair Hs biological process
G-quadruplex DNA unwinding Hs biological process
positive regulation of DNA replication Hs biological process
metal ion binding Hs molecular function
iron-sulfur cluster binding Hs molecular function
4 iron, 4 sulfur cluster binding Hs molecular function
nucleic acid phosphodiester bond hydrolysis Hs biological process

GO (Blast)

49 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
tRNA binding Hs molecular function 164 5.36e-41
nucleotide binding Hs molecular function 709 0.0
nuclear chromosome, telomeric region Hs cellular component 709 0.0
chromatin Hs cellular component 158 5.97e-39
P-body Hs cellular component 158 5.97e-39
nucleic acid binding Hs molecular function 164 5.36e-41
DNA binding Hs molecular function 709 0.0
DNA helicase activity Hs molecular function 709 0.0
chromatin binding Hs molecular function 158 5.97e-39
single-stranded DNA binding Hs molecular function 164 5.36e-41
RNA binding Hs molecular function 164 5.36e-41
catalytic activity Hs molecular function 709 0.0
ATP-dependent RNA helicase activity Hs molecular function 158 5.97e-39
helicase activity Hs molecular function 709 0.0
nuclease activity Hs molecular function 709 0.0
endonuclease activity Hs molecular function 709 0.0
protein binding Hs molecular function 709 0.0
ATP binding Hs molecular function 709 0.0
nucleus Hs cellular component 709 0.0
nucleoplasm Hs cellular component 709 0.0
cytoplasm Hs cellular component 164 5.36e-41
mitochondrion Hs cellular component 709 0.0
gamma DNA polymerase complex Hs cellular component 709 0.0
cytosol Hs cellular component 158 5.97e-39
DNA-dependent ATPase activity Hs molecular function 164 5.36e-41
transcription factor binding Hs molecular function 164 5.36e-41
RNA-dependent ATPase activity Hs molecular function 164 5.36e-41
zinc ion binding Hs molecular function 164 5.36e-41
membrane Hs cellular component 164 5.36e-41
hydrolase activity Hs molecular function 709 0.0
ATPase activity Hs molecular function 709 0.0
site-specific endodeoxyribonuclease activity, specific for altered base Hs molecular function 709 0.0
5'-flap endonuclease activity Hs molecular function 709 0.0
axon Hs cellular component 164 5.36e-41
growth cone Hs cellular component 164 5.36e-41
intracellular ribonucleoprotein complex Hs cellular component 164 5.36e-41
ATP-dependent 5'-3' RNA helicase activity Hs molecular function 164 5.36e-41
exon-exon junction complex Hs cellular component 158 5.97e-39
telomeric DNA binding Hs molecular function 158 5.97e-39
mitochondrial nucleoid Hs cellular component 709 0.0
cell projection Hs cellular component 164 5.36e-41
ribosome binding Hs molecular function 164 5.36e-41
5'-3' DNA helicase activity Hs molecular function 709 0.0
ATP-dependent 5'-3' DNA helicase activity Hs molecular function 164 5.36e-41
single-stranded DNA-dependent ATPase activity Hs molecular function 709 0.0
supraspliceosomal complex Hs cellular component 158 5.97e-39
metal ion binding Hs molecular function 709 0.0
iron-sulfur cluster binding Hs molecular function 709 0.0
4 iron, 4 sulfur cluster binding Hs molecular function 709 0.0

GO (InterProScan)

3 results

GO Term Analysis Type e-value
5'-flap endonuclease activity PANTHER molecular function 1.3E-208
DNA replication, Okazaki fragment processing PANTHER biological process 1.3E-208
single-stranded DNA-dependent ATPase activity PANTHER molecular function 1.3E-208

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