Gene Card
Best human hits
FZD10; FZD4; FZD9
Unique Gene ID
Cirobu.g00003073
Gene Model ID
KH2012:KH.C12.511
Location
KhC12:4385069..4394707
Transcript Models and Sequences
cien55364
Plate: VES78_A24
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
GPCR_2-like | ProSiteProfiles | GPCR, family 2-like |
Frizzled_dom | Pfam | Frizzled domain |
Frizzled/Smoothened_TM | SMART | Frizzled/Smoothened, transmembrane domain |
Frizzled_dom | SMART | Frizzled domain |
Frizzled/SFRP | PANTHER | Frizzled/secreted frizzled-related protein |
Frizzled_dom_sf | Gene3D | Frizzled cysteine-rich domain superfamily |
Frizzled_dom | ProSiteProfiles | Frizzled domain |
Frizzled/Smoothened_TM | PRINTS | Frizzled/Smoothened, transmembrane domain |
Frizzled/Smoothened_TM | Pfam | Frizzled/Smoothened, transmembrane domain |
Frizzled_dom_sf | SUPERFAMILY | Frizzled cysteine-rich domain superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
signal transducer activity | Orthology | molecular function |
transmembrane signaling receptor activity | Orthology | molecular function |
G-protein coupled receptor activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
endoplasmic reticulum membrane | Orthology | cellular component |
Golgi apparatus | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
integral component of plasma membrane | Orthology | cellular component |
signal transduction | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
G-protein coupled receptor signaling pathway | Orthology | biological process |
multicellular organism development | Orthology | biological process |
nervous system development | Orthology | biological process |
cell surface | Orthology | cellular component |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
neuron differentiation | Orthology | biological process |
ubiquitin protein ligase binding | Blast | molecular function |
mitochondrial membrane | Orthology | cellular component |
signaling receptor activity | Blast | molecular function |
protein homodimerization activity | Orthology | molecular function |
positive regulation of apoptotic process | Orthology | biological process |
positive regulation of GTPase activity | Orthology | biological process |
protein heterodimerization activity | Orthology | molecular function |
perinuclear region of cytoplasm | Orthology | cellular component |
membrane organization | Orthology | biological process |
extracellular exosome | Blast | cellular component |
positive regulation of canonical Wnt signaling pathway | Orthology | biological process |
organelle organization | Orthology | biological process |
apoptotic process | Orthology | biological process |
cell proliferation | Orthology | biological process |
generation of neurons | Orthology | biological process |
cell division | Orthology | biological process |
nervous system process | Orthology | biological process |
cell-cell signaling | Orthology | biological process |
immune system process | Orthology | biological process |
animal organ development | Orthology | biological process |
cell differentiation | Orthology | biological process |
cell projection membrane | Orthology | cellular component |
cytoskeletal part | Orthology | cellular component |
regulation of GTPase activity | Orthology | biological process |
positive regulation of catalytic activity | Orthology | biological process |
intracellular signal transduction | Orthology | biological process |
protein serine/threonine kinase activity | Orthology | molecular function |
cellular response to stress | Orthology | biological process |
positive regulation of signal transduction | Orthology | biological process |
negative regulation of apoptotic process | Orthology | biological process |
cellular process | Orthology | biological process |
cell | Orthology | cellular component |
response to lipid | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
mitochondrion | Orthology | cellular component |
negative regulation of signal transduction | Orthology | biological process |
anatomical structure development | Orthology | biological process |
wound healing | Orthology | biological process |
positive regulation of cell proliferation | Orthology | biological process |
binding | Blast | molecular function |
cell junction | Blast | cellular component |
intracellular organelle part | Blast | cellular component |
whole membrane | Blast | cellular component |
cytoplasmic vesicle | Blast | cellular component |
bounding membrane of organelle | Blast | cellular component |
macromolecular complex | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
amyloid-beta binding | Hs | molecular function | 410 | 5.87e-138 |
signal transducer activity | Hs | molecular function | 508 | 1.80e-175 |
transmembrane signaling receptor activity | Hs | molecular function | 508 | 1.80e-175 |
G-protein coupled receptor activity | Hs | molecular function | 508 | 1.80e-175 |
protein binding | Hs | molecular function | 508 | 1.80e-175 |
nucleoplasm | Hs | cellular component | 508 | 1.80e-175 |
cytoplasm | Hs | cellular component | 508 | 1.80e-175 |
endoplasmic reticulum membrane | Hs | cellular component | 468 | 1.59e-159 |
Golgi apparatus | Hs | cellular component | 468 | 1.59e-159 |
plasma membrane | Hs | cellular component | 508 | 1.80e-175 |
integral component of plasma membrane | Hs | cellular component | 508 | 1.80e-175 |
cell-cell junction | Hs | cellular component | 410 | 5.87e-138 |
cell surface | Hs | cellular component | 508 | 1.80e-175 |
membrane | Hs | cellular component | 508 | 1.80e-175 |
integral component of membrane | Hs | cellular component | 508 | 1.80e-175 |
Wnt-protein binding | Hs | molecular function | 508 | 1.80e-175 |
cytokine binding | Hs | molecular function | 410 | 5.87e-138 |
PDZ domain binding | Hs | molecular function | 410 | 5.87e-138 |
dendrite | Hs | cellular component | 410 | 5.87e-138 |
clathrin-coated vesicle membrane | Hs | cellular component | 410 | 5.87e-138 |
clathrin-coated endocytic vesicle membrane | Hs | cellular component | 410 | 5.87e-138 |
filopodium membrane | Hs | cellular component | 468 | 1.59e-159 |
ubiquitin protein ligase binding | Hs | molecular function | 410 | 5.87e-138 |
mitochondrial membrane | Hs | cellular component | 468 | 1.59e-159 |
signaling receptor activity | Hs | molecular function | 410 | 5.87e-138 |
protein homodimerization activity | Hs | molecular function | 468 | 1.59e-159 |
Wnt-activated receptor activity | Hs | molecular function | 508 | 1.80e-175 |
protein heterodimerization activity | Hs | molecular function | 468 | 1.59e-159 |
perinuclear region of cytoplasm | Hs | cellular component | 468 | 1.59e-159 |
extracellular exosome | Hs | cellular component | 410 | 5.87e-138 |
amyloid-beta complex | Hs | cellular component | 410 | 5.87e-138 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
transmembrane signaling receptor activity | ProSiteProfiles | molecular function | 32.934 |
protein binding | SMART | molecular function | 1.1E-43 |
cell surface receptor signaling pathway | SMART | biological process | 1.4E-157 |
membrane | SMART | cellular component | 1.4E-157 |