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GENE CARD

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Gene Card

Best human hits

FZD10; FZD4; FZD9

Unique Gene ID

Cirobu.g00003073

Gene Model ID

KH2012:KH.C12.511

Location

KhC12:4385069..4394707

Transcript Models and Sequences

  KH2012:KH.C12.511.v1.A.SL1-1

External Database Gene Card

External database links

No result

Collections

Gateway full ORF

1 result

cien55364

Plate: VES78_A24

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

10 results

IPR Term Analysis Definition
GPCR_2-like ProSiteProfiles GPCR, family 2-like
Frizzled_dom Pfam Frizzled domain
Frizzled/Smoothened_TM SMART Frizzled/Smoothened, transmembrane domain
Frizzled_dom SMART Frizzled domain
Frizzled/SFRP PANTHER Frizzled/secreted frizzled-related protein
Frizzled_dom_sf Gene3D Frizzled cysteine-rich domain superfamily
Frizzled_dom ProSiteProfiles Frizzled domain
Frizzled/Smoothened_TM PRINTS Frizzled/Smoothened, transmembrane domain
Frizzled/Smoothened_TM Pfam Frizzled/Smoothened, transmembrane domain
Frizzled_dom_sf SUPERFAMILY Frizzled cysteine-rich domain superfamily

GOSlim

65 results

GO Term Annotation Origin Type
signal transducer activity Orthology molecular function
transmembrane signaling receptor activity Orthology molecular function
G-protein coupled receptor activity Orthology molecular function
protein binding Orthology molecular function
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
endoplasmic reticulum membrane Orthology cellular component
Golgi apparatus Orthology cellular component
plasma membrane Orthology cellular component
integral component of plasma membrane Orthology cellular component
signal transduction Orthology biological process
cell surface receptor signaling pathway Orthology biological process
G-protein coupled receptor signaling pathway Orthology biological process
multicellular organism development Orthology biological process
nervous system development Orthology biological process
cell surface Orthology cellular component
membrane Orthology cellular component
integral component of membrane Orthology cellular component
neuron differentiation Orthology biological process
ubiquitin protein ligase binding Blast molecular function
mitochondrial membrane Orthology cellular component
signaling receptor activity Blast molecular function
protein homodimerization activity Orthology molecular function
positive regulation of apoptotic process Orthology biological process
positive regulation of GTPase activity Orthology biological process
protein heterodimerization activity Orthology molecular function
perinuclear region of cytoplasm Orthology cellular component
membrane organization Orthology biological process
extracellular exosome Blast cellular component
positive regulation of canonical Wnt signaling pathway Orthology biological process
organelle organization Orthology biological process
apoptotic process Orthology biological process
cell proliferation Orthology biological process
generation of neurons Orthology biological process
cell division Orthology biological process
nervous system process Orthology biological process
cell-cell signaling Orthology biological process
immune system process Orthology biological process
animal organ development Orthology biological process
cell differentiation Orthology biological process
cell projection membrane Orthology cellular component
cytoskeletal part Orthology cellular component
regulation of GTPase activity Orthology biological process
positive regulation of catalytic activity Orthology biological process
intracellular signal transduction Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
cellular response to stress Orthology biological process
positive regulation of signal transduction Orthology biological process
negative regulation of apoptotic process Orthology biological process
cellular process Orthology biological process
cell Orthology cellular component
response to lipid Orthology biological process
cellular response to organic substance Orthology biological process
mitochondrion Orthology cellular component
negative regulation of signal transduction Orthology biological process
anatomical structure development Orthology biological process
wound healing Orthology biological process
positive regulation of cell proliferation Orthology biological process
binding Blast molecular function
cell junction Blast cellular component
intracellular organelle part Blast cellular component
whole membrane Blast cellular component
cytoplasmic vesicle Blast cellular component
bounding membrane of organelle Blast cellular component
macromolecular complex Blast cellular component

GO (Orthology)

48 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
ossification Hs biological process
release of cytochrome c from mitochondria Hs biological process
signal transducer activity Hs molecular function
transmembrane signaling receptor activity Hs molecular function
G-protein coupled receptor activity Hs molecular function
protein binding Hs molecular function
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
endoplasmic reticulum membrane Hs cellular component
Golgi apparatus Hs cellular component
plasma membrane Hs cellular component
integral component of plasma membrane Hs cellular component
signal transduction Hs biological process
cell surface receptor signaling pathway Hs biological process
G-protein coupled receptor signaling pathway Hs biological process
multicellular organism development Hs biological process
nervous system development Hs biological process
neuroblast proliferation Hs biological process
learning or memory Hs biological process
cell surface Hs cellular component
membrane Hs cellular component
integral component of membrane Hs cellular component
Wnt signaling pathway Hs biological process
Wnt-protein binding Hs molecular function
neuron differentiation Hs biological process
B cell differentiation Hs biological process
positive regulation of bone mineralization Hs biological process
filopodium membrane Hs cellular component
mitochondrial membrane Hs cellular component
regulation of actin cytoskeleton organization Hs biological process
negative regulation of GTPase activity Hs biological process
non-canonical Wnt signaling pathway Hs biological process
protein homodimerization activity Hs molecular function
Wnt-activated receptor activity Hs molecular function
positive regulation of apoptotic process Hs biological process
positive regulation of JUN kinase activity Hs biological process
negative regulation of neuron apoptotic process Hs biological process
positive regulation of GTPase activity Hs biological process
protein heterodimerization activity Hs molecular function
perinuclear region of cytoplasm Hs cellular component
regulation of cytosolic calcium ion concentration Hs biological process
canonical Wnt signaling pathway Hs biological process
negative regulation of cell cycle arrest Hs biological process
cellular response to retinoic acid Hs biological process
positive regulation of canonical Wnt signaling pathway Hs biological process
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway Hs biological process
bone regeneration Hs biological process
positive regulation of neural precursor cell proliferation Hs biological process

GO (Blast)

31 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
amyloid-beta binding Hs molecular function 410 5.87e-138
signal transducer activity Hs molecular function 508 1.80e-175
transmembrane signaling receptor activity Hs molecular function 508 1.80e-175
G-protein coupled receptor activity Hs molecular function 508 1.80e-175
protein binding Hs molecular function 508 1.80e-175
nucleoplasm Hs cellular component 508 1.80e-175
cytoplasm Hs cellular component 508 1.80e-175
endoplasmic reticulum membrane Hs cellular component 468 1.59e-159
Golgi apparatus Hs cellular component 468 1.59e-159
plasma membrane Hs cellular component 508 1.80e-175
integral component of plasma membrane Hs cellular component 508 1.80e-175
cell-cell junction Hs cellular component 410 5.87e-138
cell surface Hs cellular component 508 1.80e-175
membrane Hs cellular component 508 1.80e-175
integral component of membrane Hs cellular component 508 1.80e-175
Wnt-protein binding Hs molecular function 508 1.80e-175
cytokine binding Hs molecular function 410 5.87e-138
PDZ domain binding Hs molecular function 410 5.87e-138
dendrite Hs cellular component 410 5.87e-138
clathrin-coated vesicle membrane Hs cellular component 410 5.87e-138
clathrin-coated endocytic vesicle membrane Hs cellular component 410 5.87e-138
filopodium membrane Hs cellular component 468 1.59e-159
ubiquitin protein ligase binding Hs molecular function 410 5.87e-138
mitochondrial membrane Hs cellular component 468 1.59e-159
signaling receptor activity Hs molecular function 410 5.87e-138
protein homodimerization activity Hs molecular function 468 1.59e-159
Wnt-activated receptor activity Hs molecular function 508 1.80e-175
protein heterodimerization activity Hs molecular function 468 1.59e-159
perinuclear region of cytoplasm Hs cellular component 468 1.59e-159
extracellular exosome Hs cellular component 410 5.87e-138
amyloid-beta complex Hs cellular component 410 5.87e-138

GO (InterProScan)

4 results

GO Term Analysis Type e-value
transmembrane signaling receptor activity ProSiteProfiles molecular function 32.934
protein binding SMART molecular function 1.1E-43
cell surface receptor signaling pathway SMART biological process 1.4E-157
membrane SMART cellular component 1.4E-157