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GENE CARD

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Gene Card

Best human hits

CRK; CRKL; GRAP

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00003211

Gene Model ID

KH2012:KH.C12.637

Location

KhC12:1624667..1627241

Transcript Models and Sequences

  KH2012:KH.C12.637.v1.A.SL1-1

External Database Gene Card

External database links

1 result

Database Gene ID
NCBI Reference Sequence XM_002130671.3
Collections

Gateway full ORF

2 results

cien124778

Plate: VES89_B18

cien124803

Plate: VES89_M19

Gene collection 1 (N. Satoh)

2 results

cicl009c07

Plate: R1CiGC09k10

cicl025l14

Plate: R1CiGC11l03

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

11 results

IPR Term Analysis Definition
SH3_domain Pfam SH3 domain
SH2 PRINTS SH2 domain
SH3-like_dom_sf SUPERFAMILY SH3-like domain superfamily
SH2 Pfam SH2 domain
SH3_domain SMART SH3 domain
SH3_domain PRINTS SH3 domain
SH3_domain ProSiteProfiles SH3 domain
SH2 SMART SH2 domain
SH2 ProSiteProfiles SH2 domain
SH2_dom_sf SUPERFAMILY SH2 domain superfamily
SH2_dom_sf Gene3D SH2 domain superfamily

GOSlim

51 results

GO Term Annotation Origin Type
blood vessel development Orthology biological process
RNA binding Orthology molecular function
signal transducer activity Orthology molecular function
receptor binding Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
endosome Orthology cellular component
cytosol Orthology cellular component
plasma membrane Orthology cellular component
regulation of transcription from RNA polymerase II promoter Orthology biological process
heart development Orthology biological process
cytoskeletal protein binding Orthology molecular function
positive regulation of cell proliferation Orthology biological process
regulation of signal transduction Orthology biological process
positive regulation of signal transduction Orthology biological process
membrane Orthology cellular component
cytokine-mediated signaling pathway Orthology biological process
enzyme binding Orthology molecular function
macromolecular complex Orthology cellular component
intracellular signal transduction Orthology biological process
identical protein binding Orthology molecular function
regulation of GTPase activity Orthology biological process
membrane raft Orthology cellular component
extracellular exosome Orthology cellular component
positive regulation of catalytic activity Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
cellular response to stress Orthology biological process
protein phosphorylation Orthology biological process
small GTPase mediated signal transduction Orthology biological process
multicellular organism development Orthology biological process
cell morphogenesis Orthology biological process
animal organ development Orthology biological process
anatomical structure morphogenesis Orthology biological process
cytoskeleton Orthology cellular component
organelle organization Orthology biological process
response to oxidative stress Orthology biological process
regulation of molecular function Orthology biological process
cell adhesion molecule binding Orthology molecular function
cell surface receptor signaling pathway Orthology biological process
immune system process Orthology biological process
cellular response to organic substance Orthology biological process
cell morphogenesis involved in differentiation Orthology biological process
cell adhesion Orthology biological process
response to organic substance Orthology biological process
protein kinase binding Orthology molecular function
cell motility Orthology biological process
protein kinase activity Blast molecular function
intracellular part Blast cellular component
plasma membrane part Blast cellular component

GO (Orthology)

58 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
activation of MAPKK activity Hs biological process
blood vessel development Hs biological process
phosphotyrosine residue binding Hs molecular function
response to yeast Hs biological process
RNA binding Hs molecular function
signal transducer activity Hs molecular function
SH3/SH2 adaptor activity Hs molecular function
insulin-like growth factor receptor binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
endosome Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
regulation of transcription from RNA polymerase II promoter Hs biological process
JNK cascade Hs biological process
Ras protein signal transduction Hs biological process
pattern specification process Hs biological process
heart development Hs biological process
cytoskeletal protein binding Hs molecular function
positive regulation of cell proliferation Hs biological process
regulation of cell shape Hs biological process
animal organ morphogenesis Hs biological process
anterior/posterior pattern specification Hs biological process
regulation of signal transduction Hs biological process
positive regulation of signal transduction Hs biological process
actin cytoskeleton Hs cellular component
membrane Hs cellular component
SH3 domain binding Hs molecular function
cytokine-mediated signaling pathway Hs biological process
enzyme binding Hs molecular function
protein domain specific binding Hs molecular function
protein binding, bridging Hs molecular function
regulation of actin cytoskeleton organization Hs biological process
macromolecular complex Hs cellular component
intracellular signal transduction Hs biological process
SH2 domain binding Hs molecular function
response to hydrogen peroxide Hs biological process
identical protein binding Hs molecular function
regulation of GTPase activity Hs biological process
regulation of protein binding Hs biological process
protein self-association Hs molecular function
membrane raft Hs cellular component
cadherin binding Hs molecular function
protein phosphorylated amino acid binding Hs molecular function
ephrin receptor binding Hs molecular function
vascular endothelial growth factor receptor signaling pathway Hs biological process
ephrin receptor signaling pathway Hs biological process
thymus development Hs biological process
parathyroid gland development Hs biological process
extracellular exosome Hs cellular component
cellular response to transforming growth factor beta stimulus Hs biological process
scaffold protein binding Hs molecular function
positive regulation of substrate adhesion-dependent cell spreading Hs biological process
response to peptide Hs biological process
protein tyrosine kinase binding Hs molecular function
negative regulation of cell motility Hs biological process

GO (Blast)

33 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
phosphotyrosine residue binding Hs molecular function 301 1.25e-102
RNA binding Hs molecular function 301 1.25e-102
non-membrane spanning protein tyrosine kinase activity Hs molecular function 91.3 7.26e-22
signal transducer activity Hs molecular function 301 1.25e-102
SH3/SH2 adaptor activity Hs molecular function 301 1.25e-102
receptor binding Hs molecular function 91.3 7.26e-22
insulin-like growth factor receptor binding Hs molecular function 278 1.80e-93
protein binding Hs molecular function 301 1.25e-102
nucleus Hs cellular component 278 1.80e-93
nucleoplasm Hs cellular component 301 1.25e-102
cytoplasm Hs cellular component 301 1.25e-102
endosome Hs cellular component 301 1.25e-102
cytosol Hs cellular component 301 1.25e-102
plasma membrane Hs cellular component 278 1.80e-93
cytoskeletal protein binding Hs molecular function 278 1.80e-93
actin cytoskeleton Hs cellular component 278 1.80e-93
membrane Hs cellular component 278 1.80e-93
SH3 domain binding Hs molecular function 278 1.80e-93
enzyme binding Hs molecular function 278 1.80e-93
protein domain specific binding Hs molecular function 278 1.80e-93
protein binding, bridging Hs molecular function 278 1.80e-93
extrinsic component of cytoplasmic side of plasma membrane Hs cellular component 91.3 7.26e-22
macromolecular complex Hs cellular component 278 1.80e-93
SH2 domain binding Hs molecular function 278 1.80e-93
identical protein binding Hs molecular function 301 1.25e-102
protein self-association Hs molecular function 278 1.80e-93
membrane raft Hs cellular component 278 1.80e-93
cadherin binding Hs molecular function 301 1.25e-102
protein phosphorylated amino acid binding Hs molecular function 278 1.80e-93
ephrin receptor binding Hs molecular function 278 1.80e-93
extracellular exosome Hs cellular component 301 1.25e-102
scaffold protein binding Hs molecular function 278 1.80e-93
protein tyrosine kinase binding Hs molecular function 278 1.80e-93

GO (InterProScan)

1 result

GO Term Analysis Type e-value
protein binding SMART molecular function 1.0E-17

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