Gene Card
Best human hits
FLNA; FLNB; FLNC
Unique Gene ID
Cirobu.g00003249
Gene Model ID
KH2012:KH.C12.671
Location
KhC12:3447852..3506040
Transcript Models and Sequences
KH2012:KH.C12.671.v1.A.nonSL3-1
KH2012:KH.C12.671.v1.A.SL1-1
KH2012:KH.C12.671.v2.A.SL2-1
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000022213 |
cien205183
Plate: VES102_P04
cilv016m19
Plate: R1CiGC26k24
cilv074e12
Plate: R1CiGC44f03
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Filamin/ABP280_repeat-like | ProSiteProfiles | Filamin/ABP280 repeat-like |
Ig_E-set | SUPERFAMILY | Immunoglobulin E-set |
Ig-like_fold | Gene3D | Immunoglobulin-like fold |
CH-domain | ProSiteProfiles | Calponin homology domain |
FLN_C | PANTHER | Filamin C |
Actinin_actin-bd_CS | ProSitePatterns | Actinin-type actin-binding domain, conserved site |
CH-domain | SMART | Calponin homology domain |
CH-domain | Pfam | Calponin homology domain |
CH_dom_sf | SUPERFAMILY | CH domain superfamily |
CH_dom_sf | Gene3D | CH domain superfamily |
Filamin/ABP280_rpt | SMART | Filamin/ABP280 repeat |
Filamin/ABP280_repeat-like | Pfam | Filamin/ABP280 repeat-like |
CH-domain | CDD | Calponin homology domain |
GO Term | Annotation Origin | Type |
---|---|---|
RNA binding | Orthology | molecular function |
actin binding | Orthology | molecular function |
signal transducer activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
extracellular region | Orthology | cellular component |
nucleus | Orthology | cellular component |
nucleolus | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
cytoskeleton | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
brush border | Orthology | cellular component |
focal adhesion | Orthology | cellular component |
signal transduction | Orthology | biological process |
multicellular organism development | Orthology | biological process |
cytoskeletal protein binding | Orthology | molecular function |
transcription factor binding | Orthology | molecular function |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
kinase binding | Orthology | molecular function |
cell projection organization | Orthology | biological process |
cell differentiation | Orthology | biological process |
identical protein binding | Orthology | molecular function |
protein homodimerization activity | Orthology | molecular function |
neuronal cell body | Orthology | cellular component |
negative regulation of apoptotic process | Orthology | biological process |
establishment of protein localization | Orthology | biological process |
perinuclear region of cytoplasm | Orthology | cellular component |
actin filament binding | Orthology | molecular function |
extracellular exosome | Orthology | cellular component |
receptor binding | Orthology | molecular function |
cytoskeletal part | Orthology | cellular component |
membrane organization | Orthology | biological process |
organelle organization | Orthology | biological process |
cell development | Orthology | biological process |
animal organ development | Orthology | biological process |
cell morphogenesis involved in differentiation | Orthology | biological process |
cell junction | Orthology | cellular component |
cell periphery | Orthology | cellular component |
cytoplasmic part | Orthology | cellular component |
cell | Orthology | cellular component |
cellular protein localization | Orthology | biological process |
regulation of catalytic activity | Orthology | biological process |
intracellular signal transduction | Orthology | biological process |
G-protein coupled receptor signaling pathway | Orthology | biological process |
negative regulation of signal transduction | Orthology | biological process |
metal ion transport | Orthology | biological process |
molecular function regulator | Orthology | molecular function |
transmembrane transport | Orthology | biological process |
monovalent inorganic cation transport | Orthology | biological process |
enzyme binding | Orthology | molecular function |
cell migration | Orthology | biological process |
brain development | Orthology | biological process |
organelle part | Orthology | cellular component |
intracellular non-membrane-bounded organelle | Orthology | cellular component |
blood coagulation | Orthology | biological process |
cellular process | Orthology | biological process |
intracellular organelle part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
macromolecular complex binding | Orthology | molecular function |
protein metabolic process | Orthology | biological process |
mRNA metabolic process | Orthology | biological process |
transcription from RNA polymerase II promoter | Orthology | biological process |
protein localization to membrane | Orthology | biological process |
transcription factor activity, sequence-specific DNA binding | Orthology | molecular function |
positive regulation of signal transduction | Orthology | biological process |
regulation of molecular function | Orthology | biological process |
wound healing | Orthology | biological process |
anatomical structure morphogenesis | Orthology | biological process |
cell adhesion molecule binding | Orthology | molecular function |
cytoplasmic vesicle | Orthology | cellular component |
cell adhesion | Orthology | biological process |
innate immune response | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
microtubule-based process | Orthology | biological process |
positive regulation of cell proliferation | Orthology | biological process |
generation of neurons | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
G-protein coupled receptor binding | Hs | molecular function | 1864 | 0.0 |
stress fiber | Hs | cellular component | 1822 | 0.0 |
RNA binding | Hs | molecular function | 1864 | 0.0 |
actin binding | Hs | molecular function | 1922 | 0.0 |
signal transducer activity | Hs | molecular function | 1864 | 0.0 |
protein binding | Hs | molecular function | 1922 | 0.0 |
extracellular region | Hs | cellular component | 1864 | 0.0 |
nucleus | Hs | cellular component | 1864 | 0.0 |
nucleolus | Hs | cellular component | 1864 | 0.0 |
cytoplasm | Hs | cellular component | 1922 | 0.0 |
cytosol | Hs | cellular component | 1922 | 0.0 |
cytoskeleton | Hs | cellular component | 1922 | 0.0 |
actin filament | Hs | cellular component | 1864 | 0.0 |
plasma membrane | Hs | cellular component | 1922 | 0.0 |
brush border | Hs | cellular component | 1822 | 0.0 |
cell-cell junction | Hs | cellular component | 1864 | 0.0 |
focal adhesion | Hs | cellular component | 1922 | 0.0 |
cell cortex | Hs | cellular component | 1864 | 0.0 |
cytoskeletal protein binding | Hs | molecular function | 1922 | 0.0 |
transcription factor binding | Hs | molecular function | 1864 | 0.0 |
potassium channel regulator activity | Hs | molecular function | 1864 | 0.0 |
actin cytoskeleton | Hs | cellular component | 1864 | 0.0 |
membrane | Hs | cellular component | 1922 | 0.0 |
integral component of membrane | Hs | cellular component | 1822 | 0.0 |
sarcoplasm | Hs | cellular component | 1922 | 0.0 |
Rho GTPase binding | Hs | molecular function | 1864 | 0.0 |
Ral GTPase binding | Hs | molecular function | 1864 | 0.0 |
kinase binding | Hs | molecular function | 1864 | 0.0 |
Z disc | Hs | cellular component | 1922 | 0.0 |
ankyrin binding | Hs | molecular function | 1922 | 0.0 |
cortical cytoskeleton | Hs | cellular component | 1864 | 0.0 |
small GTPase binding | Hs | molecular function | 1864 | 0.0 |
Myb complex | Hs | cellular component | 1864 | 0.0 |
mu-type opioid receptor binding | Hs | molecular function | 1864 | 0.0 |
filamentous actin | Hs | cellular component | 1864 | 0.0 |
Fc-gamma receptor I complex binding | Hs | molecular function | 1864 | 0.0 |
sarcolemma | Hs | cellular component | 1922 | 0.0 |
identical protein binding | Hs | molecular function | 1822 | 0.0 |
protein homodimerization activity | Hs | molecular function | 1864 | 0.0 |
neuronal cell body | Hs | cellular component | 1864 | 0.0 |
costamere | Hs | cellular component | 1922 | 0.0 |
dendritic shaft | Hs | cellular component | 1864 | 0.0 |
ion channel binding | Hs | molecular function | 1864 | 0.0 |
cadherin binding | Hs | molecular function | 1864 | 0.0 |
phagocytic vesicle | Hs | cellular component | 1822 | 0.0 |
SMAD binding | Hs | molecular function | 1864 | 0.0 |
Rac GTPase binding | Hs | molecular function | 1864 | 0.0 |
perinuclear region of cytoplasm | Hs | cellular component | 1864 | 0.0 |
actin filament binding | Hs | molecular function | 1922 | 0.0 |
GTPase binding | Hs | molecular function | 1864 | 0.0 |
extracellular exosome | Hs | cellular component | 1864 | 0.0 |
apical dendrite | Hs | cellular component | 1864 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein binding | SMART | molecular function | 2.6E-42 |
actin filament binding | PANTHER | molecular function | 0.0 |