Gene Card
Best human hits
DHTKD1; OGDH; OGDHL
Unique Gene ID
Cirobu.g00003269
Gene Model ID
KH2012:KH.C12.69
Location
KhC12:1218326..1236637
Transcript Models and Sequences
KH2012:KH.C12.69.v1.B.SL1-1
KH2012:KH.C12.69.v1.B.SL2-1
KH2012:KH.C12.69.v2.B.SL1-1
KH2012:KH.C12.69.v2.B.SL2-1
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000005831 |
ENSEMBL | ENSCING00000021189 |
NCBI Reference Sequence | XM_002121044.4 |
cien42817
Plate: VES77_C02
cima865125
Plate: VES65_I15
cien126125
Plate: VES90_B01
cien204756
Plate: VES102_D03
ciad060o19
Plate: R1CiGC06a18
cieg076l15
Plate: R1CiGC40e18
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
2oxoglutarate_DH_E1 | PANTHER | 2-oxoglutarate dehydrogenase E1 component |
THDP-binding | SUPERFAMILY | Thiamin diphosphate-binding fold |
2-oxogl_dehyd_N | Pfam | 2-oxoglutarate dehydrogenase E1 component, N-terminal domain |
KGD_C | Pfam | Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal |
DH_E1 | Pfam | Dehydrogenase, E1 component |
Transketolase-like_Pyr-bd | Pfam | Transketolase-like, pyrimidine-binding domain |
Transketolase-like_Pyr-bd | SMART | Transketolase-like, pyrimidine-binding domain |
2oxoglutarate_DH_E1 | PIRSF | 2-oxoglutarate dehydrogenase E1 component |
GO Term | Annotation Origin | Type |
---|---|---|
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
mitochondrion | Orthology | cellular component |
mitochondrial matrix | Orthology | cellular component |
metabolic process | Orthology | biological process |
mitochondrial membrane | Orthology | cellular component |
metal ion binding | Orthology | molecular function |
oxidation-reduction process | Orthology | biological process |
catalytic activity | Orthology | molecular function |
cellular metabolic process | Orthology | biological process |
nucleobase-containing compound metabolic process | Orthology | biological process |
kinase activity | Orthology | molecular function |
organic substance metabolic process | Orthology | biological process |
phosphate-containing compound metabolic process | Orthology | biological process |
brain development | Orthology | biological process |
cation binding | Orthology | molecular function |
small molecule binding | Orthology | molecular function |
anion binding | Orthology | molecular function |
heterocyclic compound binding | Orthology | molecular function |
organic cyclic compound binding | Orthology | molecular function |
coenzyme binding | Orthology | molecular function |
cytoplasmic part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
oxoglutarate dehydrogenase (succinyl-transferring) activity | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
mitochondrion | Hs | cellular component |
mitochondrial matrix | Hs | cellular component |
generation of precursor metabolites and energy | Hs | biological process |
glycolytic process | Hs | biological process |
tricarboxylic acid cycle | Hs | biological process |
2-oxoglutarate metabolic process | Hs | biological process |
succinyl-CoA metabolic process | Hs | biological process |
NADH metabolic process | Hs | biological process |
metabolic process | Hs | biological process |
oxidoreductase activity | Hs | molecular function |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Hs | molecular function |
cerebellar cortex development | Hs | biological process |
thalamus development | Hs | biological process |
thiamine pyrophosphate binding | Hs | molecular function |
heat shock protein binding | Hs | molecular function |
mitochondrial membrane | Hs | cellular component |
oxoglutarate dehydrogenase (NAD+) activity | Hs | molecular function |
oxoglutarate dehydrogenase complex | Hs | cellular component |
metal ion binding | Hs | molecular function |
chaperone binding | Hs | molecular function |
oxidation-reduction process | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
oxoglutarate dehydrogenase (succinyl-transferring) activity | Hs | molecular function | 640 | 0.0 |
protein binding | Hs | molecular function | 618 | 0.0 |
nucleus | Hs | cellular component | 640 | 0.0 |
mitochondrion | Hs | cellular component | 640 | 0.0 |
mitochondrial matrix | Hs | cellular component | 640 | 0.0 |
oxidoreductase activity | Hs | molecular function | 640 | 0.0 |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Hs | molecular function | 640 | 0.0 |
thiamine pyrophosphate binding | Hs | molecular function | 640 | 0.0 |
heat shock protein binding | Hs | molecular function | 640 | 0.0 |
mitochondrial membrane | Hs | cellular component | 640 | 0.0 |
oxoglutarate dehydrogenase (NAD+) activity | Hs | molecular function | 640 | 0.0 |
oxoglutarate dehydrogenase complex | Hs | cellular component | 640 | 0.0 |
metal ion binding | Hs | molecular function | 640 | 0.0 |
chaperone binding | Hs | molecular function | 640 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
oxoglutarate dehydrogenase (succinyl-transferring) activity | PANTHER | molecular function | 0.0 |
tricarboxylic acid cycle | PANTHER | biological process | 0.0 |
metabolic process | Pfam | biological process | 8.9E-20 |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Pfam | molecular function | 8.9E-20 |
thiamine pyrophosphate binding | PANTHER | molecular function | 0.0 |
oxidation-reduction process | PANTHER | biological process | 0.0 |