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GENE CARD

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Gene Card

Best human hits

DHTKD1; OGDH; OGDHL

Unique Gene ID

Cirobu.g00003269

Gene Model ID

KH2012:KH.C12.69

Location

KhC12:1218326..1236637

External Database Gene Card
Collections

Gateway full ORF

4 results

cien42817

Plate: VES77_C02

cima865125

Plate: VES65_I15

cien126125

Plate: VES90_B01

cien204756

Plate: VES102_D03

Gene collection 1 (N. Satoh)

2 results

ciad060o19

Plate: R1CiGC06a18

cieg076l15

Plate: R1CiGC40e18

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

8 results

IPR Term Analysis Definition
2oxoglutarate_DH_E1 PANTHER 2-oxoglutarate dehydrogenase E1 component
THDP-binding SUPERFAMILY Thiamin diphosphate-binding fold
2-oxogl_dehyd_N Pfam 2-oxoglutarate dehydrogenase E1 component, N-terminal domain
KGD_C Pfam Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal
DH_E1 Pfam Dehydrogenase, E1 component
Transketolase-like_Pyr-bd Pfam Transketolase-like, pyrimidine-binding domain
Transketolase-like_Pyr-bd SMART Transketolase-like, pyrimidine-binding domain
2oxoglutarate_DH_E1 PIRSF 2-oxoglutarate dehydrogenase E1 component

GOSlim

23 results

GO Term Annotation Origin Type
protein binding Orthology molecular function
nucleus Orthology cellular component
mitochondrion Orthology cellular component
mitochondrial matrix Orthology cellular component
metabolic process Orthology biological process
mitochondrial membrane Orthology cellular component
metal ion binding Orthology molecular function
oxidation-reduction process Orthology biological process
catalytic activity Orthology molecular function
cellular metabolic process Orthology biological process
nucleobase-containing compound metabolic process Orthology biological process
kinase activity Orthology molecular function
organic substance metabolic process Orthology biological process
phosphate-containing compound metabolic process Orthology biological process
brain development Orthology biological process
cation binding Orthology molecular function
small molecule binding Orthology molecular function
anion binding Orthology molecular function
heterocyclic compound binding Orthology molecular function
organic cyclic compound binding Orthology molecular function
coenzyme binding Orthology molecular function
cytoplasmic part Orthology cellular component
macromolecular complex Orthology cellular component

GO (Orthology)

24 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
oxoglutarate dehydrogenase (succinyl-transferring) activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
mitochondrion Hs cellular component
mitochondrial matrix Hs cellular component
generation of precursor metabolites and energy Hs biological process
glycolytic process Hs biological process
tricarboxylic acid cycle Hs biological process
2-oxoglutarate metabolic process Hs biological process
succinyl-CoA metabolic process Hs biological process
NADH metabolic process Hs biological process
metabolic process Hs biological process
oxidoreductase activity Hs molecular function
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor Hs molecular function
cerebellar cortex development Hs biological process
thalamus development Hs biological process
thiamine pyrophosphate binding Hs molecular function
heat shock protein binding Hs molecular function
mitochondrial membrane Hs cellular component
oxoglutarate dehydrogenase (NAD+) activity Hs molecular function
oxoglutarate dehydrogenase complex Hs cellular component
metal ion binding Hs molecular function
chaperone binding Hs molecular function
oxidation-reduction process Hs biological process

GO (Blast)

14 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
oxoglutarate dehydrogenase (succinyl-transferring) activity Hs molecular function 640 0.0
protein binding Hs molecular function 618 0.0
nucleus Hs cellular component 640 0.0
mitochondrion Hs cellular component 640 0.0
mitochondrial matrix Hs cellular component 640 0.0
oxidoreductase activity Hs molecular function 640 0.0
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor Hs molecular function 640 0.0
thiamine pyrophosphate binding Hs molecular function 640 0.0
heat shock protein binding Hs molecular function 640 0.0
mitochondrial membrane Hs cellular component 640 0.0
oxoglutarate dehydrogenase (NAD+) activity Hs molecular function 640 0.0
oxoglutarate dehydrogenase complex Hs cellular component 640 0.0
metal ion binding Hs molecular function 640 0.0
chaperone binding Hs molecular function 640 0.0

GO (InterProScan)

6 results

GO Term Analysis Type e-value
oxoglutarate dehydrogenase (succinyl-transferring) activity PANTHER molecular function 0.0
tricarboxylic acid cycle PANTHER biological process 0.0
metabolic process Pfam biological process 8.9E-20
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor Pfam molecular function 8.9E-20
thiamine pyrophosphate binding PANTHER molecular function 0.0
oxidation-reduction process PANTHER biological process 0.0