Aniseed - Gene card

Gene Card

Best human hits

PAH; TH; TPH2

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00004432

Gene Model ID

KH2012:KH.C2.252

Location

KhC2:6643523..6648616

Transcript Models and Sequences

KH2012:KH.C2.252.v1.A.SL1-1

External Database Gene Card

External database links

2 results

Database	Gene ID
ENSEMBL	ENSCING00000007206
NCBI Reference Sequence	NM_001032795.1

Collections

Gene collection 1 (N. Satoh)

1 result

ciad050b08

Plate: R1CiGC05g24

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Regulatory Regions

2 results

Ci-TH -3526/71 REG00000868 [ regulatory_region (extended_promoter) ]
- Ci-TH -3454/25 REG00000901 [ regulatory_region (extended_promoter) ]

Gene Phylogeny

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Gene Annotations

InterPro

8 results

IPR Term	Analysis	Definition
ArAA_hydroxylase_sf	Gene3D	Aromatic amino acid hydroxylase superfamily
ArAA_hydroxylase	PANTHER	Aromatic amino acid hydroxylase
Aromatic-AA_hydroxylase_C	ProSiteProfiles	Aromatic amino acid hydroxylase, C-terminal
Aromatic-AA_hydroxylase_C	PRINTS	Aromatic amino acid hydroxylase, C-terminal
ArAA_hydroxylase_Fe/CU_BS	ProSitePatterns	Aromatic amino acid hydroxylase, iron/copper binding site
Aromatic-AA_hydroxylase_C	Pfam	Aromatic amino acid hydroxylase, C-terminal
Aro-AA_hydroxylase_C_sf	SUPERFAMILY	Aromatic amino acid monoxygenase, C-terminal domain superfamily
Tyrosine_3-monooxygenase-like	PIRSF	Tyrosine 3-monooxygenase-like

GOSlim

57 results

GO Term	Annotation Origin	Type
response to hypoxia	Orthology	biological process
catalytic activity	Orthology	molecular function
iron ion binding	Orthology	molecular function
protein binding	Orthology	molecular function
nucleus	Orthology	cellular component
cytoplasm	Orthology	cellular component
mitochondrion	Orthology	cellular component
cytosol	Orthology	cellular component
heart development	Orthology	biological process
visual perception	Orthology	biological process
sensory perception of sound	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process
enzyme binding	Orthology	molecular function
axon	Orthology	cellular component
cytoplasmic vesicle	Orthology	cellular component
response to lipopolysaccharide	Orthology	biological process
neuron projection	Orthology	cellular component
neuronal cell body	Orthology	cellular component
metal ion binding	Orthology	molecular function
oxidation-reduction process	Orthology	biological process
extracellular exosome	Blast	cellular component
chemical synaptic transmission	Orthology	biological process
response to organic substance	Orthology	biological process
endoplasmic reticulum	Orthology	cellular component
cellular metabolic process	Orthology	biological process
organic substance metabolic process	Orthology	biological process
nervous system process	Orthology	biological process
sexual reproduction	Orthology	biological process
multicellular organismal reproductive process	Orthology	biological process
synapse part	Orthology	cellular component
endomembrane system	Orthology	cellular component
neuron part	Orthology	cellular component
cellular aromatic compound metabolic process	Orthology	biological process
response to stress	Orthology	biological process
animal organ development	Orthology	biological process
plasma membrane part	Orthology	cellular component
multicellular organism development	Orthology	biological process
response to stimulus	Orthology	biological process
organic substance transport	Orthology	biological process
small molecule binding	Orthology	molecular function
anion binding	Orthology	molecular function
brain development	Orthology	biological process
intracellular organelle part	Orthology	cellular component
organelle membrane	Orthology	cellular component
response to lipid	Orthology	biological process
whole membrane	Orthology	cellular component
melanosome	Orthology	cellular component
bounding membrane of organelle	Orthology	cellular component
heterocyclic compound binding	Orthology	molecular function
organic cyclic compound binding	Orthology	molecular function
coenzyme binding	Orthology	molecular function
cation binding	Orthology	molecular function
cellular biosynthetic process	Orthology	biological process
neuron development	Orthology	biological process
cell projection part	Orthology	cellular component
cell	Orthology	cellular component
cellular response to organic substance	Orthology	biological process

GO (Orthology)

80 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
response to hypoxia	Hs	biological process
synaptic transmission, dopaminergic	Hs	biological process
response to amphetamine	Hs	biological process
heart morphogenesis	Hs	biological process
monooxygenase activity	Hs	molecular function
tyrosine 3-monooxygenase activity	Hs	molecular function
iron ion binding	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
cytoplasm	Hs	cellular component
mitochondrion	Hs	cellular component
smooth endoplasmic reticulum	Hs	cellular component
cytosol	Hs	cellular component
dopamine biosynthetic process from tyrosine	Hs	biological process
fatty acid metabolic process	Hs	biological process
sphingolipid metabolic process	Hs	biological process
heart development	Hs	biological process
visual perception	Hs	biological process
sensory perception of sound	Hs	biological process
learning	Hs	biological process
memory	Hs	biological process
mating behavior	Hs	biological process
locomotory behavior	Hs	biological process
regulation of heart contraction	Hs	biological process
synaptic vesicle	Hs	cellular component
ferrous iron binding	Hs	molecular function
ferric iron binding	Hs	molecular function
aromatic amino acid family metabolic process	Hs	biological process
response to light stimulus	Hs	biological process
response to salt stress	Hs	biological process
anatomical structure morphogenesis	Hs	biological process
animal organ morphogenesis	Hs	biological process
cytoplasmic side of plasma membrane	Hs	cellular component
response to metal ion	Hs	biological process
response to zinc ion	Hs	biological process
multicellular organism aging	Hs	biological process
response to organic cyclic compound	Hs	biological process
response to activity	Hs	biological process
aminergic neurotransmitter loading into synaptic vesicle	Hs	biological process
oxidoreductase activity	Hs	molecular function
amino acid binding	Hs	molecular function
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	Hs	molecular function
oxygen binding	Hs	molecular function
enzyme binding	Hs	molecular function
protein domain specific binding	Hs	molecular function
cerebral cortex development	Hs	biological process
axon	Hs	cellular component
dendrite	Hs	cellular component
cytoplasmic vesicle membrane	Hs	cellular component
cytoplasmic vesicle	Hs	cellular component
response to nutrient levels	Hs	biological process
response to estradiol	Hs	biological process
response to lipopolysaccharide	Hs	biological process
melanosome membrane	Hs	cellular component
tetrahydrobiopterin binding	Hs	molecular function
response to nicotine	Hs	biological process
social behavior	Hs	biological process
dopamine binding	Hs	molecular function
neurotransmitter biosynthetic process	Hs	biological process
dopamine biosynthetic process	Hs	biological process
norepinephrine biosynthetic process	Hs	biological process
catecholamine biosynthetic process	Hs	biological process
eye photoreceptor cell development	Hs	biological process
response to drug	Hs	biological process
eating behavior	Hs	biological process
neuron projection	Hs	cellular component
neuronal cell body	Hs	cellular component
terminal bouton	Hs	cellular component
perikaryon	Hs	cellular component
response to peptide hormone	Hs	biological process
pigmentation	Hs	biological process
response to ethanol	Hs	biological process
metal ion binding	Hs	molecular function
response to steroid hormone	Hs	biological process
embryonic camera-type eye morphogenesis	Hs	biological process
cognition	Hs	biological process
response to electrical stimulus	Hs	biological process
oxidation-reduction process	Hs	biological process
response to growth factor	Hs	biological process
cellular response to glucose stimulus	Hs	biological process

GO (Blast)

35 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
catalytic activity	Hs	molecular function	346	7.01e-116
monooxygenase activity	Hs	molecular function	378	2.67e-127
phenylalanine 4-monooxygenase activity	Hs	molecular function	346	7.01e-116
tryptophan 5-monooxygenase activity	Hs	molecular function	341	2.38e-113
tyrosine 3-monooxygenase activity	Hs	molecular function	378	2.67e-127
iron ion binding	Hs	molecular function	378	2.67e-127
protein binding	Hs	molecular function	378	2.67e-127
nucleus	Hs	cellular component	378	2.67e-127
cytoplasm	Hs	cellular component	378	2.67e-127
mitochondrion	Hs	cellular component	378	2.67e-127
smooth endoplasmic reticulum	Hs	cellular component	378	2.67e-127
cytosol	Hs	cellular component	378	2.67e-127
synaptic vesicle	Hs	cellular component	378	2.67e-127
ferrous iron binding	Hs	molecular function	378	2.67e-127
ferric iron binding	Hs	molecular function	378	2.67e-127
cytoplasmic side of plasma membrane	Hs	cellular component	378	2.67e-127
oxidoreductase activity	Hs	molecular function	378	2.67e-127
amino acid binding	Hs	molecular function	378	2.67e-127
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	Hs	molecular function	378	2.67e-127
oxygen binding	Hs	molecular function	378	2.67e-127
enzyme binding	Hs	molecular function	378	2.67e-127
protein domain specific binding	Hs	molecular function	378	2.67e-127
axon	Hs	cellular component	378	2.67e-127
dendrite	Hs	cellular component	378	2.67e-127
cytoplasmic vesicle membrane	Hs	cellular component	378	2.67e-127
cytoplasmic vesicle	Hs	cellular component	378	2.67e-127
melanosome membrane	Hs	cellular component	378	2.67e-127
tetrahydrobiopterin binding	Hs	molecular function	378	2.67e-127
dopamine binding	Hs	molecular function	378	2.67e-127
neuron projection	Hs	cellular component	378	2.67e-127
neuronal cell body	Hs	cellular component	378	2.67e-127
terminal bouton	Hs	cellular component	378	2.67e-127
perikaryon	Hs	cellular component	378	2.67e-127
metal ion binding	Hs	molecular function	378	2.67e-127
extracellular exosome	Hs	cellular component	346	7.01e-116

GO (InterProScan)

5 results

GO Term	Analysis	Type	e-value
monooxygenase activity	PANTHER	molecular function	7.1E-190
iron ion binding	PANTHER	molecular function	7.1E-190
aromatic amino acid family metabolic process	PANTHER	biological process	7.1E-190
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	PIRSF	molecular function	2.0E-173
oxidation-reduction process	PANTHER	biological process	7.1E-190