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GENE CARD

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Gene Card

Best human hits

BMP5; BMP6; BMP7

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00004525

Gene Model ID

KH2012:KH.C2.336

Location

KhC2:5221495..5226232

Transcript Models and Sequences

  KH2012:KH.C2.336.v1.A.SL1-1
KH2012:KH.C2.336.v1.A.SL2-1

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000003777
NCBI Reference Sequence NM_001078196.1
Collections

Gateway full ORF

2 results

cien111718

Plate: VES87_K21

cima869841

Plate: VES66_E12

Gene collection 1 (N. Satoh)

2 results

ciad042d16

Plate: R1CiGC04j07

citb068b12

Plate: R1CiGC46m03

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

8 results

IPR Term Analysis Definition
TGF-b_C ProSiteProfiles Transforming growth factor-beta, C-terminal
TGF-b_propeptide Pfam TGF-beta, propeptide
Cystine-knot_cytokine SUPERFAMILY Cystine-knot cytokine
TGF-beta-rel PANTHER Transforming growth factor-beta-related
TGF-b_C SMART Transforming growth factor-beta, C-terminal
TGFb_CS ProSitePatterns Transforming growth factor beta, conserved site
Cystine-knot_cytokine Gene3D Cystine-knot cytokine
TGF-b_C Pfam Transforming growth factor-beta, C-terminal

GOSlim

70 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
protein binding Orthology molecular function
extracellular region Orthology cellular component
extracellular space Orthology cellular component
cytoplasm Orthology cellular component
immune response Orthology biological process
multicellular organism development Orthology biological process
axon guidance Orthology biological process
negative regulation of cell proliferation Orthology biological process
positive regulation of cell death Orthology biological process
cell differentiation Orthology biological process
vesicle Orthology cellular component
regulation of apoptotic process Orthology biological process
positive regulation of apoptotic process Orthology biological process
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
protein heterodimerization activity Orthology molecular function
cell development Orthology biological process
anatomical structure formation involved in morphogenesis Orthology biological process
neuron projection morphogenesis Orthology biological process
negative regulation of cell death Orthology biological process
system development Orthology biological process
animal organ development Orthology biological process
positive regulation of cell proliferation Orthology biological process
anatomical structure morphogenesis Orthology biological process
heart development Orthology biological process
receptor binding Orthology molecular function
molecular function regulator Orthology molecular function
regulation of signal transduction Orthology biological process
signaling receptor activity Orthology molecular function
cellular process Orthology biological process
cell Orthology cellular component
defense response Orthology biological process
anion binding Orthology molecular function
carbohydrate derivative binding Orthology molecular function
regulation of molecular function Orthology biological process
protein phosphorylation Orthology biological process
cell surface receptor signaling pathway Orthology biological process
positive regulation of signal transduction Orthology biological process
response to stimulus Orthology biological process
neuron projection development Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
cellular response to organic substance Orthology biological process
reproductive process Orthology biological process
anatomical structure development Orthology biological process
brain development Orthology biological process
extracellular region part Orthology cellular component
transcription factor activity, sequence-specific DNA binding Orthology molecular function
response to lipid Orthology biological process
cell adhesion Orthology biological process
protein localization to organelle Orthology biological process
phosphorylation Orthology biological process
regulation of cellular metabolic process Orthology biological process
signal transduction Orthology biological process
regulation of catalytic activity Orthology biological process
intracellular signal transduction Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
negative regulation of signal transduction Orthology biological process
response to organic substance Orthology biological process
neuron differentiation Orthology biological process
Notch signaling pathway Orthology biological process
cell cycle Orthology biological process
protein transport Orthology biological process
generation of neurons Orthology biological process
response to hypoxia Orthology biological process
cellular response to stress Orthology biological process
head development Orthology biological process
negative regulation of apoptotic process Orthology biological process
cell-cell signaling Orthology biological process

GO (Orthology)

104 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
skeletal system development Hs biological process
ossification Hs biological process
osteoblast differentiation Hs biological process
eye development Hs biological process
ureteric bud development Hs biological process
mesoderm formation Hs biological process
kidney development Hs biological process
epithelial to mesenchymal transition Hs biological process
positive regulation of endothelial cell proliferation Hs biological process
endochondral ossification Hs biological process
endocardial cushion formation Hs biological process
type B pancreatic cell development Hs biological process
pericardium morphogenesis Hs biological process
cytokine activity Hs molecular function
transforming growth factor beta receptor binding Hs molecular function
protein binding Hs molecular function
extracellular region Hs cellular component
extracellular space Hs cellular component
cytoplasm Hs cellular component
cellular iron ion homeostasis Hs biological process
inflammatory response Hs biological process
immune response Hs biological process
multicellular organism development Hs biological process
pattern specification process Hs biological process
axon guidance Hs biological process
salivary gland morphogenesis Hs biological process
growth factor activity Hs molecular function
heparin binding Hs molecular function
negative regulation of cell proliferation Hs biological process
embryonic pattern specification Hs biological process
animal organ morphogenesis Hs biological process
response to iron ion Hs biological process
regulation of receptor activity Hs biological process
positive regulation of epithelial to mesenchymal transition Hs biological process
negative regulation of epithelial to mesenchymal transition Hs biological process
positive regulation of peptidyl-threonine phosphorylation Hs biological process
positive regulation of pathway-restricted SMAD protein phosphorylation Hs biological process
positive regulation of cell death Hs biological process
response to activity Hs biological process
dendrite development Hs biological process
cell differentiation Hs biological process
embryonic limb morphogenesis Hs biological process
positive regulation of bone mineralization Hs biological process
BMP signaling pathway Hs biological process
male genitalia development Hs biological process
epithelial cell differentiation Hs biological process
hindbrain development Hs biological process
extracellular matrix Hs cellular component
vesicle Hs cellular component
response to magnesium ion Hs biological process
negative regulation of NF-kappaB transcription factor activity Hs biological process
positive regulation of chondrocyte differentiation Hs biological process
response to estradiol Hs biological process
response to retinoic acid Hs biological process
positive regulation of heterotypic cell-cell adhesion Hs biological process
protein localization to nucleus Hs biological process
tube morphogenesis Hs biological process
regulation of phosphorylation Hs biological process
negative regulation of phosphorylation Hs biological process
regulation of apoptotic process Hs biological process
positive regulation of apoptotic process Hs biological process
steroid hormone mediated signaling pathway Hs biological process
negative regulation of MAP kinase activity Hs biological process
regulation of MAPK cascade Hs biological process
response to peptide hormone Hs biological process
negative regulation of insulin-like growth factor receptor signaling pathway Hs biological process
ear development Hs biological process
positive regulation of cell differentiation Hs biological process
positive regulation of endothelial cell differentiation Hs biological process
negative regulation of neuron differentiation Hs biological process
positive regulation of neuron differentiation Hs biological process
positive regulation of osteoblast differentiation Hs biological process
negative regulation of Notch signaling pathway Hs biological process
negative regulation of cell cycle Hs biological process
negative regulation of mitotic nuclear division Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
protein heterodimerization activity Hs molecular function
cell development Hs biological process
camera-type eye morphogenesis Hs biological process
embryonic camera-type eye morphogenesis Hs biological process
anatomical structure formation involved in morphogenesis Hs biological process
cardiac muscle tissue development Hs biological process
branching morphogenesis of an epithelial tube Hs biological process
neuron projection morphogenesis Hs biological process
positive regulation of epithelial cell proliferation Hs biological process
positive regulation of protein secretion Hs biological process
negative regulation of neurogenesis Hs biological process
cartilage development Hs biological process
response to glucocorticoid Hs biological process
pharyngeal system development Hs biological process
embryonic skeletal joint morphogenesis Hs biological process
SMAD protein signal transduction Hs biological process
negative regulation of cell death Hs biological process
multicellular organismal iron ion homeostasis Hs biological process
BMP receptor binding Hs molecular function
cellular response to mechanical stimulus Hs biological process
cellular response to hypoxia Hs biological process
anterior head development Hs biological process
positive regulation of dendrite development Hs biological process
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors Hs biological process
negative regulation of insulin secretion Hs biological process

GO (Blast)

12 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
cytokine activity Hs molecular function 150 6.29e-39
transforming growth factor beta receptor binding Hs molecular function 150 6.29e-39
protein binding Hs molecular function 137 9.83e-35
extracellular region Hs cellular component 150 6.29e-39
extracellular space Hs cellular component 150 6.29e-39
cytoplasm Hs cellular component 150 6.29e-39
growth factor activity Hs molecular function 150 6.29e-39
heparin binding Hs molecular function 137 9.83e-35
extracellular matrix Hs cellular component 137 9.83e-35
vesicle Hs cellular component 150 6.29e-39
protein heterodimerization activity Hs molecular function 150 6.29e-39
BMP receptor binding Hs molecular function 150 6.29e-39

GO (InterProScan)

1 result

GO Term Analysis Type e-value
growth factor activity SMART molecular function 4.3E-46

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