Gene Card
Best human hits
BIVM-ERCC5; FEN1; GEN1
Unique Gene ID
Cirobu.g00004812
Gene Model ID
KH2012:KH.C2.598
Location
KhC2:4148992..4154475
Transcript Models and Sequences
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000008651 |
cima87259
Plate: VES57_A08
cima867120
Plate: VES66_N01
citb13c3
Plate: R1CiGC30d17
cieg048n10
Plate: R1CiGC23k20
n/a
You can Right Mouse Click on internal nodes, leaves and outside the tree to see multiple options adapted to your selection.
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see how you can interact with this tree
The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
HhH2 | SMART | Helix-hairpin-helix motif, class 2 |
XPG-I_dom | Pfam | XPG-I domain |
XPG/Rad2 | PRINTS | XPG/Rad2 endonuclease |
XPG_DNA_repair_N | Pfam | XPG N-terminal |
PIN-like_dom_sf | SUPERFAMILY | PIN-like domain superfamily |
5-3_exonuclease_C_sf | SUPERFAMILY | 5'-3' exonuclease, C-terminal domain superfamily |
XPG-I_dom | SMART | XPG-I domain |
XPG_DNA_repair_N | SMART | XPG N-terminal |
XPG/Rad2 | PANTHER | XPG/Rad2 endonuclease |
GO Term | Annotation Origin | Type |
---|---|---|
magnesium ion binding | Blast | molecular function |
DNA binding | Orthology | molecular function |
double-stranded DNA binding | Blast | molecular function |
catalytic activity | Orthology | molecular function |
protein binding | Blast | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
nucleolus | Blast | cellular component |
mitochondrion | Blast | cellular component |
centrosome | Orthology | cellular component |
DNA repair | Orthology | biological process |
cellular response to DNA damage stimulus | Orthology | biological process |
membrane | Blast | cellular component |
hydrolase activity | Orthology | molecular function |
macromolecular complex | Blast | cellular component |
metal ion binding | Orthology | molecular function |
extracellular exosome | Orthology | cellular component |
DNA metabolic process | Orthology | biological process |
organelle organization | Orthology | biological process |
microtubule-based process | Orthology | biological process |
mitotic cell cycle phase transition | Orthology | biological process |
intracellular non-membrane-bounded organelle | Blast | cellular component |
nuclear lumen | Blast | cellular component |
RNA metabolic process | Blast | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
double-strand break repair via homologous recombination | Hs | biological process |
DNA binding | Hs | molecular function |
catalytic activity | Hs | molecular function |
nuclease activity | Hs | molecular function |
endonuclease activity | Hs | molecular function |
endodeoxyribonuclease activity | Hs | molecular function |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
centrosome | Hs | cellular component |
DNA repair | Hs | biological process |
cellular response to DNA damage stimulus | Hs | biological process |
crossover junction endodeoxyribonuclease activity | Hs | molecular function |
regulation of centrosome duplication | Hs | biological process |
hydrolase activity | Hs | molecular function |
metal ion binding | Hs | molecular function |
extracellular exosome | Hs | cellular component |
positive regulation of mitotic cell cycle spindle assembly checkpoint | Hs | biological process |
nucleic acid phosphodiester bond hydrolysis | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
magnesium ion binding | Hs | molecular function | 103 | 1.49e-23 |
nuclear chromosome, telomeric region | Hs | cellular component | 103 | 1.49e-23 |
DNA binding | Hs | molecular function | 354 | 4.43e-110 |
damaged DNA binding | Hs | molecular function | 103 | 1.49e-23 |
double-stranded DNA binding | Hs | molecular function | 103 | 1.49e-23 |
single-stranded DNA binding | Hs | molecular function | 99.8 | 2.07e-21 |
catalytic activity | Hs | molecular function | 354 | 4.43e-110 |
nuclease activity | Hs | molecular function | 354 | 4.43e-110 |
endonuclease activity | Hs | molecular function | 354 | 4.43e-110 |
endodeoxyribonuclease activity | Hs | molecular function | 354 | 4.43e-110 |
RNA-DNA hybrid ribonuclease activity | Hs | molecular function | 103 | 1.49e-23 |
exonuclease activity | Hs | molecular function | 103 | 1.49e-23 |
protein binding | Hs | molecular function | 103 | 1.49e-23 |
nucleus | Hs | cellular component | 354 | 4.43e-110 |
nucleoplasm | Hs | cellular component | 354 | 4.43e-110 |
nucleolus | Hs | cellular component | 103 | 1.49e-23 |
mitochondrion | Hs | cellular component | 103 | 1.49e-23 |
centrosome | Hs | cellular component | 354 | 4.43e-110 |
double-stranded DNA exodeoxyribonuclease activity | Hs | molecular function | 103 | 1.49e-23 |
5'-3' exonuclease activity | Hs | molecular function | 103 | 1.49e-23 |
crossover junction endodeoxyribonuclease activity | Hs | molecular function | 354 | 4.43e-110 |
membrane | Hs | cellular component | 103 | 1.49e-23 |
hydrolase activity | Hs | molecular function | 354 | 4.43e-110 |
hydrolase activity, acting on ester bonds | Hs | molecular function | 103 | 1.49e-23 |
5'-flap endonuclease activity | Hs | molecular function | 103 | 1.49e-23 |
macromolecular complex | Hs | cellular component | 103 | 1.49e-23 |
metal ion binding | Hs | molecular function | 354 | 4.43e-110 |
flap endonuclease activity | Hs | molecular function | 103 | 1.49e-23 |
extracellular exosome | Hs | cellular component | 354 | 4.43e-110 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
DNA binding | SMART | molecular function | 0.0012 |
catalytic activity | SMART | molecular function | 0.0012 |
nuclease activity | PANTHER | molecular function | 1.7E-166 |
DNA repair | PANTHER | biological process | 1.7E-166 |