Gene Card
Best human hits
ILKAP; PPM1D; PPM1L
Unique Gene ID
Cirobu.g00004923
Gene Model ID
KH2012:KH.C2.70
Location
KhC2:6655158..6659214
Transcript Models and Sequences
KH2012:KH.C2.70.v1.A.ND2-1
KH2012:KH.C2.70.v1.A.SL1-1
KH2012:KH.C2.70.v2.A.ND3-1
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000007208 |
cien31136
Plate: VES75_F07
cien209580
Plate: VES102_C20
cieg014g09
Plate: R1CiGC17f11
citb033m20
Plate: R1CiGC32a11
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
PPM-type_phosphatase_dom | Pfam | PPM-type phosphatase domain |
PPM-type_dom_sf | Gene3D | PPM-type phosphatase domain superfamily |
PPM-type_phosphatase_dom | CDD | PPM-type phosphatase domain |
PP2C | PANTHER | Protein phosphatase 2C family |
PPM-type_phosphatase_dom | ProSiteProfiles | PPM-type phosphatase domain |
PPM-type_dom_sf | SUPERFAMILY | PPM-type phosphatase domain superfamily |
PPM-type_phosphatase_dom | SMART | PPM-type phosphatase domain |
GO Term | Annotation Origin | Type |
---|---|---|
G2/M transition of mitotic cell cycle | Orthology | biological process |
catalytic activity | Orthology | molecular function |
protein serine/threonine kinase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
endoplasmic reticulum membrane | Blast | cellular component |
cytosol | Orthology | cellular component |
transcription initiation from RNA polymerase II promoter | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
protein dephosphorylation | Orthology | biological process |
cell cycle | Orthology | biological process |
negative regulation of cell proliferation | Orthology | biological process |
response to bacterium | Orthology | biological process |
membrane | Blast | cellular component |
integral component of membrane | Blast | cellular component |
kinase activity | Blast | molecular function |
hydrolase activity | Orthology | molecular function |
cation binding | Orthology | molecular function |
metal ion binding | Orthology | molecular function |
extracellular exosome | Blast | cellular component |
DNA metabolic process | Orthology | biological process |
organelle organization | Orthology | biological process |
negative regulation of transcription, DNA-templated | Orthology | biological process |
cell communication | Orthology | biological process |
cellular response to stress | Orthology | biological process |
negative regulation of gene expression | Orthology | biological process |
protein kinase binding | Orthology | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
G2/M transition of mitotic cell cycle | Hs | biological process |
catalytic activity | Hs | molecular function |
protein serine/threonine kinase activity | Hs | molecular function |
phosphoprotein phosphatase activity | Hs | molecular function |
protein serine/threonine phosphatase activity | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
DNA methylation | Hs | biological process |
chromatin silencing | Hs | biological process |
transcription initiation from RNA polymerase II promoter | Hs | biological process |
protein phosphorylation | Hs | biological process |
protein dephosphorylation | Hs | biological process |
cell cycle | Hs | biological process |
negative regulation of cell proliferation | Hs | biological process |
cellular response to starvation | Hs | biological process |
response to radiation | Hs | biological process |
response to bacterium | Hs | biological process |
hydrolase activity | Hs | molecular function |
peptidyl-threonine dephosphorylation | Hs | biological process |
cation binding | Hs | molecular function |
negative regulation of gene expression, epigenetic | Hs | biological process |
metal ion binding | Hs | molecular function |
mitogen-activated protein kinase binding | Hs | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
catalytic activity | Hs | molecular function | 317 | 2.89e-101 |
protein serine/threonine kinase activity | Hs | molecular function | 317 | 2.89e-101 |
phosphoprotein phosphatase activity | Hs | molecular function | 317 | 2.89e-101 |
protein serine/threonine phosphatase activity | Hs | molecular function | 317 | 2.89e-101 |
protein binding | Hs | molecular function | 317 | 2.89e-101 |
nucleus | Hs | cellular component | 317 | 2.89e-101 |
nucleoplasm | Hs | cellular component | 317 | 2.89e-101 |
cytoplasm | Hs | cellular component | 317 | 2.89e-101 |
endoplasmic reticulum membrane | Hs | cellular component | 96.3 | 1.08e-21 |
cytosol | Hs | cellular component | 317 | 2.89e-101 |
membrane | Hs | cellular component | 96.3 | 1.08e-21 |
integral component of membrane | Hs | cellular component | 96.3 | 1.08e-21 |
kinase activity | Hs | molecular function | 112 | 5.12e-27 |
hydrolase activity | Hs | molecular function | 317 | 2.89e-101 |
cation binding | Hs | molecular function | 317 | 2.89e-101 |
metal ion binding | Hs | molecular function | 317 | 2.89e-101 |
mitogen-activated protein kinase binding | Hs | molecular function | 317 | 2.89e-101 |
extracellular exosome | Hs | cellular component | 96.3 | 1.08e-21 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
catalytic activity | CDD | molecular function | 5.138E-63 |
protein serine/threonine phosphatase activity | PANTHER | molecular function | 3.2E-147 |
protein dephosphorylation | PANTHER | biological process | 3.2E-147 |