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Gene Card

Best human hits

HACE1; HUWE1; UBR5

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00004976

Gene Model ID

KH2012:KH.C2.749

Location

KhC2:3970312..4032924

Transcript Models and Sequences

  KH2012:KH.C2.749.v1.B.SL1-1
KH2012:KH.C2.749.v2.A.SL1-2

External Database Gene Card

External database links

No result

Collections

Gateway full ORF

3 results

cien109023

Plate: VES87_M08

cien93187

Plate: VES84_G21

cien146838

Plate: VES93_E06

Gene collection 1 (N. Satoh)

4 results

cieg014j10

Plate: R1CiGC17j15

ciad010m24

Plate: R1CiGC02e23

cieg020c11

Plate: R1CiGC18l11

ciad045m08

Plate: R1CiGC04l08

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

13 results

IPR Term Analysis Definition
E3_UbLigase_EDD_UBA Pfam E3 ubiquitin ligase EDD, ubiquitin-associated domain
E3_UbLigase_EDD_UBA CDD E3 ubiquitin ligase EDD, ubiquitin-associated domain
Znf_UBR ProSiteProfiles Zinc finger, UBR-type
Znf_UBR SMART Zinc finger, UBR-type
RCC1/BLIP-II SUPERFAMILY Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
Hect_E3_ubiquitin_ligase SUPERFAMILY HECT, E3 ligase catalytic domain
HECT_dom SMART HECT domain
HECT_dom Pfam HECT domain
PABP_HYD ProSiteProfiles Polyadenylate-binding protein/Hyperplastic disc protein
HECT_dom ProSiteProfiles HECT domain
PABP_HYD SMART Polyadenylate-binding protein/Hyperplastic disc protein
PABP_HYD Pfam Polyadenylate-binding protein/Hyperplastic disc protein
PABP-dom SUPERFAMILY PABC (PABP) domain

GOSlim

38 results

GO Term Annotation Origin Type
Golgi membrane Blast cellular component
protein polyubiquitination Orthology biological process
DNA binding Blast molecular function
RNA binding Orthology molecular function
ubiquitin-protein transferase activity Orthology molecular function
binding Blast molecular function
protein binding Orthology molecular function
extracellular region Blast cellular component
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Blast cellular component
endoplasmic reticulum Blast cellular component
Golgi apparatus Blast cellular component
cytosol Orthology cellular component
DNA repair Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
zinc ion binding Orthology molecular function
cell proliferation Orthology biological process
positive regulation of gene expression Orthology biological process
membrane Orthology cellular component
protein ubiquitination Orthology biological process
nuclear body Blast cellular component
transferase activity Orthology molecular function
macromolecular complex Orthology cellular component
metal ion binding Orthology molecular function
perinuclear region of cytoplasm Orthology cellular component
extracellular exosome Blast cellular component
positive regulation of canonical Wnt signaling pathway Orthology biological process
proteolysis Orthology biological process
signal transduction Orthology biological process
response to lipid Orthology biological process
cellular response to organic substance Orthology biological process
organelle organization Orthology biological process
enzyme binding Blast molecular function
intracellular organelle part Blast cellular component
cytoplasmic vesicle Blast cellular component
endomembrane system Blast cellular component
intracellular organelle lumen Blast cellular component

GO (Orthology)

28 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
protein polyubiquitination Hs biological process
RNA binding Hs molecular function
ubiquitin-protein transferase activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytosol Hs cellular component
DNA repair Hs biological process
ubiquitin-dependent protein catabolic process Hs biological process
cellular response to DNA damage stimulus Hs biological process
zinc ion binding Hs molecular function
cell proliferation Hs biological process
positive regulation of gene expression Hs biological process
membrane Hs cellular component
protein ubiquitination Hs biological process
transferase activity Hs molecular function
macromolecular complex Hs cellular component
positive regulation of protein import into nucleus, translocation Hs biological process
ubiquitin-ubiquitin ligase activity Hs molecular function
ubiquitin binding Hs molecular function
metal ion binding Hs molecular function
perinuclear region of cytoplasm Hs cellular component
progesterone receptor signaling pathway Hs biological process
ubiquitin protein ligase activity Hs molecular function
protein K48-linked ubiquitination Hs biological process
positive regulation of canonical Wnt signaling pathway Hs biological process
negative regulation of histone H2A K63-linked ubiquitination Hs biological process
negative regulation of double-strand break repair Hs biological process

GO (Blast)

29 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
Golgi membrane Hs cellular component 134 4.92e-31
DNA binding Hs molecular function 117 1.44e-25
RNA binding Hs molecular function 1780 0.0
ubiquitin-protein transferase activity Hs molecular function 1780 0.0
binding Hs molecular function 117 1.44e-25
protein binding Hs molecular function 1780 0.0
extracellular region Hs cellular component 117 1.44e-25
nucleus Hs cellular component 1780 0.0
nucleoplasm Hs cellular component 1780 0.0
cytoplasm Hs cellular component 134 4.92e-31
endoplasmic reticulum Hs cellular component 134 4.92e-31
Golgi apparatus Hs cellular component 134 4.92e-31
cytosol Hs cellular component 1780 0.0
zinc ion binding Hs molecular function 1780 0.0
membrane Hs cellular component 1780 0.0
nuclear body Hs cellular component 134 4.92e-31
transferase activity Hs molecular function 1780 0.0
Rab GTPase binding Hs molecular function 134 4.92e-31
Golgi cisterna membrane Hs cellular component 134 4.92e-31
macromolecular complex Hs cellular component 1780 0.0
ubiquitin-ubiquitin ligase activity Hs molecular function 1780 0.0
secretory granule lumen Hs cellular component 117 1.44e-25
ubiquitin binding Hs molecular function 1780 0.0
metal ion binding Hs molecular function 1780 0.0
Rac GTPase binding Hs molecular function 134 4.92e-31
perinuclear region of cytoplasm Hs cellular component 1780 0.0
ubiquitin protein ligase activity Hs molecular function 1780 0.0
extracellular exosome Hs cellular component 117 1.44e-25
ficolin-1-rich granule lumen Hs cellular component 117 1.44e-25

GO (InterProScan)

4 results

GO Term Analysis Type e-value
RNA binding SUPERFAMILY molecular function 1.28E-17
ubiquitin-protein transferase activity SMART molecular function 6.2E-91
zinc ion binding SMART molecular function 1.4E-23
ubiquitin binding Pfam molecular function 4.0E-29

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