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Gene Card

Best human hits

DLX1; MSX1; MSX2

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00005203

Gene Model ID

KH2012:KH.C2.957

Location

KhC2:5773511..5775832

Transcript Models and Sequences

  KH2012:KH.C2.957.v1.A.nonSL1-1

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000009129
NCBI Reference Sequence NM_001032496.1
Collections

Gateway full ORF

2 results

cien92596

Plate: VES84_L19

cien157648

Plate: VES94_F17

Gene collection 1 (N. Satoh)

2 results

citb031n15

Plate: R1CiGC31b24

cign067l18

Plate: R1CiGC42h24

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

14 results

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term Analysis Definition
Homeobox_dom ProSiteProfiles Homeobox domain
Homeobox-like_sf SUPERFAMILY Homeobox-like domain superfamily
Homeobox_metazoa PRINTS Homeobox domain, metazoa
Homeobox_dom CDD Homeobox domain
Homeobox_dom Pfam Homeobox domain
Homeobox_CS ProSitePatterns Homeobox, conserved site
Homeobox_dom SMART Homeobox domain

GOSlim

48 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
cell morphogenesis Orthology biological process
RNA polymerase II regulatory region sequence-specific DNA binding Orthology molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcription factor activity, transcription factor binding Orthology molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Orthology molecular function
DNA binding Orthology molecular function
chromatin binding Blast molecular function
transcription cofactor activity Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytosol Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
transcription from RNA polymerase II promoter Orthology biological process
multicellular organism development Orthology biological process
heart development Orthology biological process
transcription factor binding Orthology molecular function
negative regulation of cell proliferation Orthology biological process
nuclear speck Orthology cellular component
cell differentiation Orthology biological process
wound healing Orthology biological process
regulation of apoptotic process Orthology biological process
negative regulation of apoptotic process Orthology biological process
sequence-specific DNA binding Orthology molecular function
transcription regulatory region DNA binding Orthology molecular function
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
animal organ development Orthology biological process
cell development Orthology biological process
anatomical structure morphogenesis Orthology biological process
brain development Orthology biological process
signal transduction Orthology biological process
regulation of gene expression Orthology biological process
cellular component organization Orthology biological process
cell surface receptor signaling pathway Orthology biological process
cellular response to organic substance Orthology biological process
positive regulation of signal transduction Orthology biological process
protein localization to organelle Orthology biological process
cell migration Orthology biological process
regulation of molecular function Orthology biological process
anatomical structure development Orthology biological process
head development Orthology biological process
response to lipid Orthology biological process
intracellular signal transduction Orthology biological process
positive regulation of apoptotic process Orthology biological process

GO (Orthology)

66 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
cell morphogenesis Hs biological process
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
transcription factor activity, transcription factor binding Hs molecular function
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function
ossification Hs biological process
osteoblast differentiation Hs biological process
epithelial to mesenchymal transition Hs biological process
p53 binding Hs molecular function
chondrocyte development Hs biological process
osteoblast development Hs biological process
heart morphogenesis Hs biological process
outflow tract morphogenesis Hs biological process
DNA binding Hs molecular function
transcription cofactor activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytosol Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
transcription from RNA polymerase II promoter Hs biological process
multicellular organism development Hs biological process
heart development Hs biological process
muscle organ development Hs biological process
transcription factor binding Hs molecular function
negative regulation of cell proliferation Hs biological process
anterior/posterior pattern specification Hs biological process
nuclear speck Hs cellular component
pituitary gland development Hs biological process
signal transduction involved in regulation of gene expression Hs biological process
negative regulation of cell growth Hs biological process
embryonic limb morphogenesis Hs biological process
BMP signaling pathway Hs biological process
positive regulation of BMP signaling pathway Hs biological process
forebrain development Hs biological process
midbrain development Hs biological process
protein localization to nucleus Hs biological process
embryonic hindlimb morphogenesis Hs biological process
wound healing, spreading of epidermal cells Hs biological process
enhancer binding Hs molecular function
wound healing Hs biological process
odontogenesis Hs biological process
regulation of apoptotic process Hs biological process
negative regulation of apoptotic process Hs biological process
negative regulation of DNA binding Hs biological process
sequence-specific DNA binding Hs molecular function
transcription regulatory region DNA binding Hs molecular function
positive regulation of osteoblast differentiation Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
stem cell differentiation Hs biological process
protein stabilization Hs biological process
cartilage development Hs biological process
palate development Hs biological process
face morphogenesis Hs biological process
bone morphogenesis Hs biological process
cranial suture morphogenesis Hs biological process
cartilage morphogenesis Hs biological process
BMP signaling pathway involved in heart development Hs biological process
cellular response to estradiol stimulus Hs biological process
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator Hs biological process
negative regulation of transcription regulatory region DNA binding Hs biological process

GO (Blast)

19 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function 141 3.30e-40
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 141 3.30e-40
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function 139 6.16e-39
transcription factor activity, transcription factor binding Hs molecular function 141 3.30e-40
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function 141 3.30e-40
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function 139 6.16e-39
p53 binding Hs molecular function 139 6.16e-39
DNA binding Hs molecular function 141 3.30e-40
chromatin binding Hs molecular function 85.1 3.32e-19
transcription cofactor activity Hs molecular function 141 3.30e-40
protein binding Hs molecular function 141 3.30e-40
nucleus Hs cellular component 141 3.30e-40
nucleoplasm Hs cellular component 139 6.16e-39
cytosol Hs cellular component 141 3.30e-40
transcription factor binding Hs molecular function 141 3.30e-40
nuclear speck Hs cellular component 141 3.30e-40
enhancer binding Hs molecular function 139 6.16e-39
sequence-specific DNA binding Hs molecular function 141 3.30e-40
transcription regulatory region DNA binding Hs molecular function 141 3.30e-40

GO (InterProScan)

3 results

GO Term Analysis Type e-value
DNA binding SMART molecular function 2.1E-24
regulation of transcription, DNA-templated ProSitePatterns biological process
sequence-specific DNA binding ProSitePatterns molecular function

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