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GENE CARD

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Gene Card

Best human hits

HIP1; TLN1; TLN2

Unique Gene ID

Cirobu.g00005295

Gene Model ID

KH2012:KH.C3.14

Location

KhC3:2104950..2127583

External Database Gene Card

External database links

1 result

Database Gene ID
ENSEMBL ENSCING00000009522
Collections

Gene collection 1 (N. Satoh)

1 result

cilv003p23

Plate: R1CiGC25k21

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Gene Annotations

InterPro

19 results

IPR Term Analysis Definition
Alpha-catenin/vinculin-like_sf SUPERFAMILY Alpha-catenin/vinculin-like superfamily
PH-like_dom_sf Gene3D PH-like domain superfamily
I/LWEQ_dom_sf SUPERFAMILY I/LWEQ domain superfamily
FERM_central Pfam FERM central domain
FERM_N Pfam FERM, N-terminal
FERM/acyl-CoA-bd_prot_sf Gene3D FERM/acyl-CoA-binding protein superfamily
Talin_cent Pfam Talin, central
FERM_central CDD FERM central domain
FERM_domain ProSiteProfiles FERM domain
ILWEQ_dom Pfam I/LWEQ domain
FERM_2 SUPERFAMILY FERM superfamily, second domain
FERM_f0 Pfam Talin, N-terminal F0 domain
ILWEQ_dom ProDom I/LWEQ domain
Talin1/2-RS CDD Talin-1/2, rod-segment
ILWEQ_dom SMART I/LWEQ domain
Band_41_domain SMART Band 4.1 domain
Talin_cent_sf SUPERFAMILY Talin, central domain superfamily
Vinculin-bd_dom Pfam Vinculin-binding site-containing domain
ILWEQ_dom ProSiteProfiles I/LWEQ domain

GOSlim

51 results

GO Term Annotation Origin Type
actin binding Orthology molecular function
integrin binding Orthology molecular function
structural molecule activity Orthology molecular function
protein binding Orthology molecular function
extracellular region Orthology cellular component
nucleus Blast cellular component
cytoplasm Orthology cellular component
Golgi apparatus Blast cellular component
cytosol Orthology cellular component
cytoskeleton Orthology cellular component
plasma membrane Orthology cellular component
focal adhesion Orthology cellular component
cell adhesion Orthology biological process
cell surface Orthology cellular component
endomembrane system Blast cellular component
membrane Orthology cellular component
cell junction Orthology cellular component
cytoplasmic vesicle Blast cellular component
protein homodimerization activity Blast molecular function
cell projection Orthology cellular component
intracellular membrane-bounded organelle Blast cellular component
synapse Orthology cellular component
protein heterodimerization activity Blast molecular function
actin filament binding Orthology molecular function
membrane organization Orthology biological process
extracellular exosome Orthology cellular component
postsynapse Blast cellular component
plasma membrane region Orthology cellular component
cell leading edge Orthology cellular component
anion binding Orthology molecular function
organelle organization Orthology biological process
cell Orthology cellular component
cellular protein localization Orthology biological process
cell surface receptor signaling pathway Orthology biological process
cytoskeletal protein binding Orthology molecular function
cell projection membrane Orthology cellular component
cell adhesion molecule binding Orthology molecular function
blood coagulation Orthology biological process
cellular process Orthology biological process
receptor binding Blast molecular function
whole membrane Blast cellular component
plasma membrane part Blast cellular component
bounding membrane of organelle Blast cellular component
macromolecular complex Blast cellular component
intracellular organelle part Blast cellular component
intracellular part Blast cellular component
macromolecular complex binding Blast molecular function
synapse part Blast cellular component
neuron part Blast cellular component
synaptic membrane Blast cellular component
postsynaptic membrane Blast cellular component

GO (Orthology)

36 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
ruffle Hs cellular component
phosphatidylserine binding Hs molecular function
platelet degranulation Hs biological process
actin binding Hs molecular function
integrin binding Hs molecular function
structural molecule activity Hs molecular function
structural constituent of cytoskeleton Hs molecular function
protein binding Hs molecular function
extracellular region Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
cytoskeleton Hs cellular component
plasma membrane Hs cellular component
focal adhesion Hs cellular component
muscle contraction Hs biological process
cytoskeletal anchoring at plasma membrane Hs biological process
cell-cell junction assembly Hs biological process
cell-substrate junction assembly Hs biological process
cell adhesion Hs biological process
integrin-mediated signaling pathway Hs biological process
cell surface Hs cellular component
actin cytoskeleton Hs cellular component
membrane Hs cellular component
viral process Hs biological process
vinculin binding Hs molecular function
cell junction Hs cellular component
LIM domain binding Hs molecular function
cortical actin cytoskeleton organization Hs biological process
ruffle membrane Hs cellular component
phosphatidylinositol binding Hs molecular function
cell projection Hs cellular component
synapse Hs cellular component
cadherin binding Hs molecular function
actin filament binding Hs molecular function
extracellular exosome Hs cellular component
platelet aggregation Hs biological process

GO (Blast)

51 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
ruffle Hs cellular component 2848 0.0
phosphatidylserine binding Hs molecular function 2818 0.0
actin binding Hs molecular function 2848 0.0
epidermal growth factor receptor binding Hs molecular function 102 1.64e-21
integrin binding Hs molecular function 2818 0.0
structural molecule activity Hs molecular function 2848 0.0
structural constituent of cytoskeleton Hs molecular function 2848 0.0
protein binding Hs molecular function 2848 0.0
phospholipid binding Hs molecular function 102 1.64e-21
extracellular region Hs cellular component 2818 0.0
nucleus Hs cellular component 102 1.64e-21
cytoplasm Hs cellular component 2848 0.0
Golgi apparatus Hs cellular component 102 1.64e-21
cytosol Hs cellular component 2818 0.0
cytoskeleton Hs cellular component 2848 0.0
plasma membrane Hs cellular component 2848 0.0
focal adhesion Hs cellular component 2848 0.0
cell surface Hs cellular component 2818 0.0
endomembrane system Hs cellular component 102 1.64e-21
actin cytoskeleton Hs cellular component 2848 0.0
membrane Hs cellular component 2848 0.0
vinculin binding Hs molecular function 2818 0.0
cell junction Hs cellular component 2848 0.0
AP-2 adaptor complex Hs cellular component 102 1.64e-21
clathrin-coated vesicle Hs cellular component 102 1.64e-21
LIM domain binding Hs molecular function 2818 0.0
clathrin binding Hs molecular function 102 1.64e-21
clathrin-coated vesicle membrane Hs cellular component 102 1.64e-21
extrinsic component of cytoplasmic side of plasma membrane Hs cellular component 102 1.64e-21
cytoplasmic vesicle Hs cellular component 102 1.64e-21
clathrin light chain binding Hs molecular function 102 1.64e-21
phosphatidylinositol-3-phosphate binding Hs molecular function 102 1.64e-21
ruffle membrane Hs cellular component 2818 0.0
phosphatidylinositol binding Hs molecular function 2818 0.0
glutamate receptor binding Hs molecular function 102 1.64e-21
AP-2 adaptor complex binding Hs molecular function 102 1.64e-21
clathrin adaptor activity Hs molecular function 102 1.64e-21
protein homodimerization activity Hs molecular function 102 1.64e-21
cell projection Hs cellular component 2818 0.0
intracellular membrane-bounded organelle Hs cellular component 102 1.64e-21
phosphatidylinositol-3,4-bisphosphate binding Hs molecular function 102 1.64e-21
synapse Hs cellular component 2848 0.0
cadherin binding Hs molecular function 2818 0.0
protein heterodimerization activity Hs molecular function 102 1.64e-21
actin filament binding Hs molecular function 2848 0.0
extracellular exosome Hs cellular component 2818 0.0
phosphatidylinositol-3,5-bisphosphate binding Hs molecular function 102 1.64e-21
presynapse Hs cellular component 102 1.64e-21
postsynapse Hs cellular component 102 1.64e-21
extrinsic component of presynaptic membrane Hs cellular component 102 1.64e-21
extrinsic component of postsynaptic membrane Hs cellular component 102 1.64e-21

GO (InterProScan)

8 results

GO Term Analysis Type e-value
ruffle Pfam cellular component 1.5E-55
actin binding SMART molecular function 1.4E-86
structural constituent of cytoskeleton Pfam molecular function 1.5E-55
cytoskeleton ProSiteProfiles cellular component 56.511
focal adhesion Pfam cellular component 1.5E-55
cytoskeletal anchoring at plasma membrane Pfam biological process 1.5E-55
cell adhesion SUPERFAMILY biological process 6.28E-33
actin filament binding SUPERFAMILY molecular function 6.28E-33