Gene Card
Best human hits
HIP1; TLN1; TLN2
Unique Gene ID
Cirobu.g00005295
Gene Model ID
KH2012:KH.C3.14
Location
KhC3:2104950..2127583
Transcript Models and Sequences
KH2012:KH.C3.14.v1.A.SL1-1
KH2012:KH.C3.14.v1.A.SL2-1
KH2012:KH.C3.14.v2.B.SL1-1
KH2012:KH.C3.14.v2.B.SL2-1
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000009522 |
cilv003p23
Plate: R1CiGC25k21
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Alpha-catenin/vinculin-like_sf | SUPERFAMILY | Alpha-catenin/vinculin-like superfamily |
PH-like_dom_sf | Gene3D | PH-like domain superfamily |
I/LWEQ_dom_sf | SUPERFAMILY | I/LWEQ domain superfamily |
FERM_central | Pfam | FERM central domain |
FERM_N | Pfam | FERM, N-terminal |
FERM/acyl-CoA-bd_prot_sf | Gene3D | FERM/acyl-CoA-binding protein superfamily |
Talin_cent | Pfam | Talin, central |
FERM_central | CDD | FERM central domain |
FERM_domain | ProSiteProfiles | FERM domain |
ILWEQ_dom | Pfam | I/LWEQ domain |
FERM_2 | SUPERFAMILY | FERM superfamily, second domain |
FERM_f0 | Pfam | Talin, N-terminal F0 domain |
ILWEQ_dom | ProDom | I/LWEQ domain |
Talin1/2-RS | CDD | Talin-1/2, rod-segment |
ILWEQ_dom | SMART | I/LWEQ domain |
Band_41_domain | SMART | Band 4.1 domain |
Talin_cent_sf | SUPERFAMILY | Talin, central domain superfamily |
Vinculin-bd_dom | Pfam | Vinculin-binding site-containing domain |
ILWEQ_dom | ProSiteProfiles | I/LWEQ domain |
GO Term | Annotation Origin | Type |
---|---|---|
actin binding | Orthology | molecular function |
integrin binding | Orthology | molecular function |
structural molecule activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
extracellular region | Orthology | cellular component |
nucleus | Blast | cellular component |
cytoplasm | Orthology | cellular component |
Golgi apparatus | Blast | cellular component |
cytosol | Orthology | cellular component |
cytoskeleton | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
focal adhesion | Orthology | cellular component |
cell adhesion | Orthology | biological process |
cell surface | Orthology | cellular component |
endomembrane system | Blast | cellular component |
membrane | Orthology | cellular component |
cell junction | Orthology | cellular component |
cytoplasmic vesicle | Blast | cellular component |
protein homodimerization activity | Blast | molecular function |
cell projection | Orthology | cellular component |
intracellular membrane-bounded organelle | Blast | cellular component |
synapse | Orthology | cellular component |
protein heterodimerization activity | Blast | molecular function |
actin filament binding | Orthology | molecular function |
membrane organization | Orthology | biological process |
extracellular exosome | Orthology | cellular component |
postsynapse | Blast | cellular component |
plasma membrane region | Orthology | cellular component |
cell leading edge | Orthology | cellular component |
anion binding | Orthology | molecular function |
organelle organization | Orthology | biological process |
cell | Orthology | cellular component |
cellular protein localization | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
cytoskeletal protein binding | Orthology | molecular function |
cell projection membrane | Orthology | cellular component |
cell adhesion molecule binding | Orthology | molecular function |
blood coagulation | Orthology | biological process |
cellular process | Orthology | biological process |
receptor binding | Blast | molecular function |
whole membrane | Blast | cellular component |
plasma membrane part | Blast | cellular component |
bounding membrane of organelle | Blast | cellular component |
macromolecular complex | Blast | cellular component |
intracellular organelle part | Blast | cellular component |
intracellular part | Blast | cellular component |
macromolecular complex binding | Blast | molecular function |
synapse part | Blast | cellular component |
neuron part | Blast | cellular component |
synaptic membrane | Blast | cellular component |
postsynaptic membrane | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
ruffle | Hs | cellular component |
phosphatidylserine binding | Hs | molecular function |
platelet degranulation | Hs | biological process |
actin binding | Hs | molecular function |
integrin binding | Hs | molecular function |
structural molecule activity | Hs | molecular function |
structural constituent of cytoskeleton | Hs | molecular function |
protein binding | Hs | molecular function |
extracellular region | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
cytoskeleton | Hs | cellular component |
plasma membrane | Hs | cellular component |
focal adhesion | Hs | cellular component |
muscle contraction | Hs | biological process |
cytoskeletal anchoring at plasma membrane | Hs | biological process |
cell-cell junction assembly | Hs | biological process |
cell-substrate junction assembly | Hs | biological process |
cell adhesion | Hs | biological process |
integrin-mediated signaling pathway | Hs | biological process |
cell surface | Hs | cellular component |
actin cytoskeleton | Hs | cellular component |
membrane | Hs | cellular component |
viral process | Hs | biological process |
vinculin binding | Hs | molecular function |
cell junction | Hs | cellular component |
LIM domain binding | Hs | molecular function |
cortical actin cytoskeleton organization | Hs | biological process |
ruffle membrane | Hs | cellular component |
phosphatidylinositol binding | Hs | molecular function |
cell projection | Hs | cellular component |
synapse | Hs | cellular component |
cadherin binding | Hs | molecular function |
actin filament binding | Hs | molecular function |
extracellular exosome | Hs | cellular component |
platelet aggregation | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
ruffle | Hs | cellular component | 2848 | 0.0 |
phosphatidylserine binding | Hs | molecular function | 2818 | 0.0 |
actin binding | Hs | molecular function | 2848 | 0.0 |
epidermal growth factor receptor binding | Hs | molecular function | 102 | 1.64e-21 |
integrin binding | Hs | molecular function | 2818 | 0.0 |
structural molecule activity | Hs | molecular function | 2848 | 0.0 |
structural constituent of cytoskeleton | Hs | molecular function | 2848 | 0.0 |
protein binding | Hs | molecular function | 2848 | 0.0 |
phospholipid binding | Hs | molecular function | 102 | 1.64e-21 |
extracellular region | Hs | cellular component | 2818 | 0.0 |
nucleus | Hs | cellular component | 102 | 1.64e-21 |
cytoplasm | Hs | cellular component | 2848 | 0.0 |
Golgi apparatus | Hs | cellular component | 102 | 1.64e-21 |
cytosol | Hs | cellular component | 2818 | 0.0 |
cytoskeleton | Hs | cellular component | 2848 | 0.0 |
plasma membrane | Hs | cellular component | 2848 | 0.0 |
focal adhesion | Hs | cellular component | 2848 | 0.0 |
cell surface | Hs | cellular component | 2818 | 0.0 |
endomembrane system | Hs | cellular component | 102 | 1.64e-21 |
actin cytoskeleton | Hs | cellular component | 2848 | 0.0 |
membrane | Hs | cellular component | 2848 | 0.0 |
vinculin binding | Hs | molecular function | 2818 | 0.0 |
cell junction | Hs | cellular component | 2848 | 0.0 |
AP-2 adaptor complex | Hs | cellular component | 102 | 1.64e-21 |
clathrin-coated vesicle | Hs | cellular component | 102 | 1.64e-21 |
LIM domain binding | Hs | molecular function | 2818 | 0.0 |
clathrin binding | Hs | molecular function | 102 | 1.64e-21 |
clathrin-coated vesicle membrane | Hs | cellular component | 102 | 1.64e-21 |
extrinsic component of cytoplasmic side of plasma membrane | Hs | cellular component | 102 | 1.64e-21 |
cytoplasmic vesicle | Hs | cellular component | 102 | 1.64e-21 |
clathrin light chain binding | Hs | molecular function | 102 | 1.64e-21 |
phosphatidylinositol-3-phosphate binding | Hs | molecular function | 102 | 1.64e-21 |
ruffle membrane | Hs | cellular component | 2818 | 0.0 |
phosphatidylinositol binding | Hs | molecular function | 2818 | 0.0 |
glutamate receptor binding | Hs | molecular function | 102 | 1.64e-21 |
AP-2 adaptor complex binding | Hs | molecular function | 102 | 1.64e-21 |
clathrin adaptor activity | Hs | molecular function | 102 | 1.64e-21 |
protein homodimerization activity | Hs | molecular function | 102 | 1.64e-21 |
cell projection | Hs | cellular component | 2818 | 0.0 |
intracellular membrane-bounded organelle | Hs | cellular component | 102 | 1.64e-21 |
phosphatidylinositol-3,4-bisphosphate binding | Hs | molecular function | 102 | 1.64e-21 |
synapse | Hs | cellular component | 2848 | 0.0 |
cadherin binding | Hs | molecular function | 2818 | 0.0 |
protein heterodimerization activity | Hs | molecular function | 102 | 1.64e-21 |
actin filament binding | Hs | molecular function | 2848 | 0.0 |
extracellular exosome | Hs | cellular component | 2818 | 0.0 |
phosphatidylinositol-3,5-bisphosphate binding | Hs | molecular function | 102 | 1.64e-21 |
presynapse | Hs | cellular component | 102 | 1.64e-21 |
postsynapse | Hs | cellular component | 102 | 1.64e-21 |
extrinsic component of presynaptic membrane | Hs | cellular component | 102 | 1.64e-21 |
extrinsic component of postsynaptic membrane | Hs | cellular component | 102 | 1.64e-21 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
ruffle | Pfam | cellular component | 1.5E-55 |
actin binding | SMART | molecular function | 1.4E-86 |
structural constituent of cytoskeleton | Pfam | molecular function | 1.5E-55 |
cytoskeleton | ProSiteProfiles | cellular component | 56.511 |
focal adhesion | Pfam | cellular component | 1.5E-55 |
cytoskeletal anchoring at plasma membrane | Pfam | biological process | 1.5E-55 |
cell adhesion | SUPERFAMILY | biological process | 6.28E-33 |
actin filament binding | SUPERFAMILY | molecular function | 6.28E-33 |