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GENE CARD

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  1. Gene 'Moocul.CG.ELv1_2.S57...'

Gene Card

Best human hits

TCF12; TCF3; TCF4

Unique Gene ID

Cirobu.g00005521

Gene Model ID

KH2012:KH.C3.348

Location

KhC3:2131671..2143571

Collections

Gateway full ORF

4 results

cien61125

Plate: VES79_O21

cima860030

Plate: VES64_F14

cien192660

Plate: VES100_M03

cien230439

Plate: VES105_P18

Gene collection 1 (N. Satoh)

4 results

cieg008b13

Plate: R1CiGC16p09

cieg039l11

Plate: R1CiGC21h18

cieg027d13

Plate: R1CiGC19n06

cieg015b06

Plate: R1CiGC17d04

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Genomicus Synteny Browser

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Regulatory Regions
Gene Phylogeny

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Gene Annotations

InterPro

6 results

IPR Term Analysis Definition
bHLH_dom Pfam Myc-type, basic helix-loop-helix (bHLH) domain
HLH_DNA-bd_sf SUPERFAMILY Helix-loop-helix DNA-binding domain superfamily
HLH_DNA-bd_sf Gene3D Helix-loop-helix DNA-binding domain superfamily
bHLH_dom SMART Myc-type, basic helix-loop-helix (bHLH) domain
bHLH_dom ProSiteProfiles Myc-type, basic helix-loop-helix (bHLH) domain
bHLH_dom CDD Myc-type, basic helix-loop-helix (bHLH) domain

GOSlim

51 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding Orthology molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
DNA binding Orthology molecular function
chromatin binding Orthology molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcription coactivator activity Orthology molecular function
transcription corepressor activity Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
transcription, DNA-templated Orthology biological process
DNA-templated transcription, initiation Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
transcription from RNA polymerase II promoter Orthology biological process
transcription initiation from RNA polymerase II promoter Orthology biological process
immune response Orthology biological process
multicellular organism development Orthology biological process
nervous system development Orthology biological process
protein C-terminus binding Orthology molecular function
transcription factor binding Orthology molecular function
positive regulation of gene expression Orthology biological process
negative regulation of gene expression Orthology biological process
nuclear speck Orthology cellular component
cell differentiation Orthology biological process
identical protein binding Orthology molecular function
protein homodimerization activity Orthology molecular function
intracellular membrane-bounded organelle Orthology cellular component
transcription regulatory region DNA binding Orthology molecular function
positive regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
protein heterodimerization activity Orthology molecular function
protein dimerization activity Orthology molecular function
intracellular non-membrane-bounded organelle Orthology cellular component
nuclear lumen Orthology cellular component
intracellular part Orthology cellular component
macromolecular complex Orthology cellular component
animal organ development Orthology biological process
angiogenesis Orthology biological process
immune system process Orthology biological process
protein kinase binding Orthology molecular function
DNA metabolic process Orthology biological process
system development Orthology biological process
cell development Orthology biological process
neuron differentiation Orthology biological process
nuclear part Orthology cellular component
cell surface receptor signaling pathway Orthology biological process
regulation of signal transduction Orthology biological process
cellular response to organic substance Orthology biological process

GO (Orthology)

64 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
nuclear chromatin Hs cellular component
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting Hs molecular function
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
transcription factor activity, TFIIB-class binding Hs molecular function
TFIIB-class transcription factor binding Hs molecular function
DNA binding Hs molecular function
chromatin binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
transcription coactivator activity Hs molecular function
transcription corepressor activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
transcription factor complex Hs cellular component
cytoplasm Hs cellular component
transcription, DNA-templated Hs biological process
DNA-templated transcription, initiation Hs biological process
regulation of transcription, DNA-templated Hs biological process
regulation of transcription from RNA polymerase II promoter Hs biological process
transcription from RNA polymerase II promoter Hs biological process
transcription initiation from RNA polymerase II promoter Hs biological process
immune response Hs biological process
multicellular organism development Hs biological process
nervous system development Hs biological process
muscle organ development Hs biological process
protein C-terminus binding Hs molecular function
transcription factor binding Hs molecular function
positive regulation of gene expression Hs biological process
negative regulation of gene expression Hs biological process
negative regulation of angiogenesis Hs biological process
nuclear speck Hs cellular component
cell differentiation Hs biological process
B cell differentiation Hs biological process
mitogen-activated protein kinase kinase kinase binding Hs molecular function
immunoglobulin V(D)J recombination Hs biological process
enhancer binding Hs molecular function
cAMP response element binding Hs molecular function
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
intracellular membrane-bounded organelle Hs cellular component
bHLH transcription factor binding Hs molecular function
protein self-association Hs molecular function
transcription regulatory region DNA binding Hs molecular function
positive regulation of neuron differentiation Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
SMAD binding Hs molecular function
protein heterodimerization activity Hs molecular function
protein dimerization activity Hs molecular function
positive regulation of sequence-specific DNA binding transcription factor activity Hs biological process
protein-DNA complex assembly Hs biological process
beta-catenin-TCF7L2 complex Hs cellular component
repressing transcription factor binding Hs molecular function
vitamin D response element binding Hs molecular function
E-box binding Hs molecular function
HMG box domain binding Hs molecular function
RNA polymerase II transcription factor complex Hs cellular component
regulation of vascular endothelial growth factor signaling pathway Hs biological process
regulation of hematopoietic stem cell differentiation Hs biological process
beta-catenin-TCF complex Hs cellular component

GO (Blast)

40 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nuclear chromatin Hs cellular component 166 1.68e-43
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function 166 1.68e-43
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 166 1.68e-43
transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting Hs molecular function 164 1.48e-42
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function 166 1.68e-43
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function 160 1.52e-41
transcription factor activity, TFIIB-class binding Hs molecular function 164 1.48e-42
TFIIB-class transcription factor binding Hs molecular function 164 1.48e-42
DNA binding Hs molecular function 166 1.68e-43
chromatin binding Hs molecular function 164 1.48e-42
transcription factor activity, sequence-specific DNA binding Hs molecular function 166 1.68e-43
transcription coactivator activity Hs molecular function 160 1.52e-41
transcription corepressor activity Hs molecular function 164 1.48e-42
protein binding Hs molecular function 166 1.68e-43
nucleus Hs cellular component 166 1.68e-43
nucleoplasm Hs cellular component 166 1.68e-43
transcription factor complex Hs cellular component 166 1.68e-43
cytoplasm Hs cellular component 166 1.68e-43
protein C-terminus binding Hs molecular function 164 1.48e-42
transcription factor binding Hs molecular function 166 1.68e-43
nuclear speck Hs cellular component 166 1.68e-43
mitogen-activated protein kinase kinase kinase binding Hs molecular function 160 1.52e-41
enhancer binding Hs molecular function 166 1.68e-43
cAMP response element binding Hs molecular function 166 1.68e-43
identical protein binding Hs molecular function 164 1.48e-42
protein homodimerization activity Hs molecular function 166 1.68e-43
intracellular membrane-bounded organelle Hs cellular component 166 1.68e-43
bHLH transcription factor binding Hs molecular function 166 1.68e-43
protein self-association Hs molecular function 164 1.48e-42
transcription regulatory region DNA binding Hs molecular function 166 1.68e-43
SMAD binding Hs molecular function 166 1.68e-43
protein heterodimerization activity Hs molecular function 166 1.68e-43
protein dimerization activity Hs molecular function 166 1.68e-43
beta-catenin-TCF7L2 complex Hs cellular component 164 1.48e-42
repressing transcription factor binding Hs molecular function 160 1.52e-41
vitamin D response element binding Hs molecular function 160 1.52e-41
E-box binding Hs molecular function 166 1.68e-43
HMG box domain binding Hs molecular function 166 1.68e-43
RNA polymerase II transcription factor complex Hs cellular component 166 1.68e-43
beta-catenin-TCF complex Hs cellular component 164 1.48e-42

GO (InterProScan)

1 result

GO Term Analysis Type e-value
protein dimerization activity Gene3D molecular function 3.9E-33