Aniseed - Gene card

Gene Card

Best human hits

EFNA1; EFNA4; EFNA5

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00005918

Gene Model ID

KH2012:KH.C3.716

Location

KhC3:2802437..2806780

Transcript Models and Sequences

KH2012:KH.C3.716.v1.A.SL1-1

External Database Gene Card

External database links

2 results

Database	Gene ID
ENSEMBL	ENSCING00000005716
NCBI Reference Sequence	NM_001078226.1

Collections

Gateway full ORF

2 results

Gene collection 1 (N. Satoh)

1 result

ciad008n17

Plate: R1CiGC01j20

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Regulatory Regions

14 results

Ci-EphrinA-d -742/-75 REG00000362 [ regulatory_region (extended_promoter) ]

Cirobu.REG.KH2013:KH.C3.2806725-2808428 REG00001013 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2013:KH.C3.2806725-2807321 REG00001014 [ regulatory_region (extended_promoter) ]
  - Cirobu.REG.KH2013:KH.C3.2806725-2807277 REG00001015 [ regulatory_region (extended_promoter) ]
    - Cirobu.REG.KH2013:KH.C3.2806725-2807227 REG00001016 [ regulatory_region (extended_promoter) ]
      - Cirobu.REG.KH2013:KH.C3.2806725-2807177 REG00001017 [ regulatory_region (extended_promoter) ]
        
        Cirobu.REG.KH2013:KH.C3.2806725-2807113 REG00001018 [ inactive_region ]

Cirobu.REG.KH2012.C3:2806773-2809874|Efna.d REG00001146 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.C3:2806773-2807200|Efna.d REG00001147 [ regulatory_region (extended_promoter) ]

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term	Analysis	Definition
Ephrin_RBD	PRINTS	Ephrin receptor-binding domain
Ephrin	PANTHER	Ephrin
Cupredoxin	Gene3D	Cupredoxin
Ephrin_RBD	ProSiteProfiles	Ephrin receptor-binding domain
Ephrin_RBD	Pfam	Ephrin receptor-binding domain
Cupredoxin	SUPERFAMILY	Cupredoxin
Ephrin_RBD	ProDom	Ephrin receptor-binding domain

GOSlim

59 results

GO Term	Annotation Origin	Type
negative regulation of transcription from RNA polymerase II promoter	Orthology	biological process
angiogenesis	Orthology	biological process
receptor binding	Orthology	molecular function
protein binding	Orthology	molecular function
extracellular region	Orthology	cellular component
plasma membrane	Orthology	cellular component
integral component of plasma membrane	Orthology	cellular component
adherens junction	Orthology	cellular component
cell-cell signaling	Orthology	biological process
multicellular organism development	Orthology	biological process
nervous system development	Orthology	biological process
axon guidance	Orthology	biological process
membrane	Orthology	cellular component
integral component of membrane	Orthology	cellular component
cell migration	Orthology	biological process
cell differentiation	Orthology	biological process
neuron differentiation	Orthology	biological process
regulation of GTPase activity	Orthology	biological process
extracellular exosome	Orthology	cellular component
cell periphery	Orthology	cellular component
protein phosphorylation	Orthology	biological process
cell surface receptor signaling pathway	Orthology	biological process
protein kinase activity	Orthology	molecular function
transmembrane signaling receptor activity	Orthology	molecular function
extracellular region part	Orthology	cellular component
membrane raft	Orthology	cellular component
plasma membrane region	Orthology	cellular component
positive regulation of catalytic activity	Orthology	biological process
animal organ development	Orthology	biological process
anatomical structure formation involved in morphogenesis	Orthology	biological process
cell adhesion	Orthology	biological process
cell morphogenesis	Orthology	biological process
enzyme activator activity	Orthology	molecular function
protein kinase binding	Orthology	molecular function
signaling receptor activity	Orthology	molecular function
regulation of signal transduction	Orthology	biological process
immune system process	Orthology	biological process
intrinsic component of membrane	Orthology	cellular component
cell surface	Orthology	cellular component
intrinsic component of plasma membrane	Orthology	cellular component
organelle organization	Orthology	biological process
cell morphogenesis involved in differentiation	Orthology	biological process
intracellular signal transduction	Orthology	biological process
negative regulation of signal transduction	Orthology	biological process
positive regulation of signal transduction	Orthology	biological process
molecular function regulator	Orthology	molecular function
chemotaxis	Orthology	biological process
axonogenesis	Orthology	biological process
regulation of cellular metabolic process	Orthology	biological process
cellular response to organic substance	Orthology	biological process
protein transport	Orthology	biological process
regulation of signaling	Orthology	biological process
microtubule-based process	Orthology	biological process
proteolysis	Orthology	biological process
response to lipid	Orthology	biological process
brain development	Orthology	biological process
synapse	Orthology	cellular component
neuronal cell body	Orthology	cellular component
cell development	Orthology	biological process

GO (Orthology)

67 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
angiogenesis	Hs	biological process
positive regulation of protein phosphorylation	Hs	biological process
transmembrane-ephrin receptor activity	Hs	molecular function
receptor binding	Hs	molecular function
neurotrophin TRKA receptor binding	Hs	molecular function
neurotrophin TRKB receptor binding	Hs	molecular function
neurotrophin TRKC receptor binding	Hs	molecular function
protein binding	Hs	molecular function
extracellular region	Hs	cellular component
basement membrane	Hs	cellular component
plasma membrane	Hs	cellular component
integral component of plasma membrane	Hs	cellular component
caveola	Hs	cellular component
adherens junction	Hs	cellular component
activation of transmembrane receptor protein tyrosine kinase activity	Hs	biological process
cell-cell signaling	Hs	biological process
multicellular organism development	Hs	biological process
nervous system development	Hs	biological process
axon guidance	Hs	biological process
negative regulation of epithelial to mesenchymal transition	Hs	biological process
notochord formation	Hs	biological process
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
cell migration	Hs	biological process
regulation of cell-cell adhesion	Hs	biological process
regulation of cell morphogenesis	Hs	biological process
cell differentiation	Hs	biological process
neuron differentiation	Hs	biological process
transmembrane receptor protein tyrosine kinase activator activity	Hs	molecular function
osteoclast differentiation	Hs	biological process
anchored component of membrane	Hs	cellular component
retinal ganglion cell axon guidance	Hs	biological process
anchored component of external side of plasma membrane	Hs	cellular component
regulation of actin cytoskeleton organization	Hs	biological process
regulation of cell adhesion mediated by integrin	Hs	biological process
substrate adhesion-dependent cell spreading	Hs	biological process
regulation of GTPase activity	Hs	biological process
negative regulation of MAPK cascade	Hs	biological process
positive regulation of MAPK cascade	Hs	biological process
regulation of blood vessel endothelial cell migration	Hs	biological process
chemorepellent activity	Hs	molecular function
regulation of angiogenesis	Hs	biological process
anchored component of plasma membrane	Hs	cellular component
bone remodeling	Hs	biological process
ephrin receptor binding	Hs	molecular function
ephrin receptor signaling pathway	Hs	biological process
collateral sprouting	Hs	biological process
regulation of peptidyl-tyrosine phosphorylation	Hs	biological process
positive regulation of peptidyl-tyrosine phosphorylation	Hs	biological process
regulation of axonogenesis	Hs	biological process
protein stabilization	Hs	biological process
negative chemotaxis	Hs	biological process
positive regulation of synapse assembly	Hs	biological process
positive regulation of protein tyrosine kinase activity	Hs	biological process
regulation of insulin secretion involved in cellular response to glucose stimulus	Hs	biological process
extracellular exosome	Hs	cellular component
regulation of microtubule cytoskeleton organization	Hs	biological process
cell periphery	Hs	cellular component
negative regulation of substrate adhesion-dependent cell spreading	Hs	biological process
negative regulation of proteolysis involved in cellular protein catabolic process	Hs	biological process
cellular response to forskolin	Hs	biological process
negative regulation of angiogenesis	Hs	biological process
olfactory bulb development	Hs	biological process
neuromuscular junction	Hs	cellular component
perikaryon	Hs	cellular component
regulation of neuron differentiation	Hs	biological process

GO (Blast)

22 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
transmembrane-ephrin receptor activity	Hs	molecular function	70.5	1.44e-14
receptor binding	Hs	molecular function	72.0	4.87e-15
neurotrophin TRKA receptor binding	Hs	molecular function	80.5	5.35e-18
neurotrophin TRKB receptor binding	Hs	molecular function	80.5	5.35e-18
neurotrophin TRKC receptor binding	Hs	molecular function	80.5	5.35e-18
protein binding	Hs	molecular function	80.5	5.35e-18
extracellular region	Hs	cellular component	72.0	4.87e-15
basement membrane	Hs	cellular component	80.5	5.35e-18
plasma membrane	Hs	cellular component	80.5	5.35e-18
integral component of plasma membrane	Hs	cellular component	72.0	4.87e-15
caveola	Hs	cellular component	80.5	5.35e-18
adherens junction	Hs	cellular component	80.5	5.35e-18
membrane	Hs	cellular component	80.5	5.35e-18
integral component of membrane	Hs	cellular component	80.5	5.35e-18
transmembrane receptor protein tyrosine kinase activator activity	Hs	molecular function	80.5	5.35e-18
anchored component of membrane	Hs	cellular component	80.5	5.35e-18
anchored component of external side of plasma membrane	Hs	cellular component	80.5	5.35e-18
chemorepellent activity	Hs	molecular function	80.5	5.35e-18
anchored component of plasma membrane	Hs	cellular component	72.0	4.87e-15
ephrin receptor binding	Hs	molecular function	80.5	5.35e-18
extracellular exosome	Hs	cellular component	72.0	4.87e-15
cell periphery	Hs	cellular component	80.5	5.35e-18

GO (InterProScan)