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GENE CARD

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Gene Card

Best human hits

HNF4A; HNF4G; RXRA

Unique Gene ID

Cirobu.g00006049

Gene Model ID

KH2012:KH.C3.84

Location

KhC3:2554856..2568789

Collections

Gateway full ORF

2 results

cien110659

Plate: VES87_H17

cima874213

Plate: VES67_J11

Gene collection 1 (N. Satoh)

1 result

ciad047g04

Plate: R1CiGC05g17

WashU Genome Browser

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

11 results

IPR Term Analysis Definition
Nucl_hrmn_rcpt_lig-bd Pfam Nuclear hormone receptor, ligand-binding domain
Znf_NHR/GATA Gene3D Zinc finger, NHR/GATA-type
Nucl_hrmn_rcpt_lig-bd SMART Nuclear hormone receptor, ligand-binding domain
Nuclear_hrmn_rcpt PRINTS Nuclear hormone receptor
NHR_like_dom_sf SUPERFAMILY Nuclear hormone receptor-like domain superfamily
Znf_hrmn_rcpt Pfam Zinc finger, nuclear hormone receptor-type
Znf_hrmn_rcpt PRINTS Zinc finger, nuclear hormone receptor-type
Znf_hrmn_rcpt ProSitePatterns Zinc finger, nuclear hormone receptor-type
Znf_hrmn_rcpt ProSiteProfiles Zinc finger, nuclear hormone receptor-type
Retinoid-X_rcpt/HNF4 PRINTS Retinoid X receptor/HNF4
Znf_hrmn_rcpt SMART Zinc finger, nuclear hormone receptor-type

GOSlim

55 results

GO Term Annotation Origin Type
RNA polymerase II regulatory region sequence-specific DNA binding Blast molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding Orthology molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Orthology molecular function
DNA binding Orthology molecular function
double-stranded DNA binding Blast molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcription coactivator activity Blast molecular function
receptor binding Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
transcription from RNA polymerase II promoter Orthology biological process
transcription initiation from RNA polymerase II promoter Orthology biological process
blood coagulation Orthology biological process
transcription factor binding Orthology molecular function
zinc ion binding Orthology molecular function
negative regulation of cell proliferation Orthology biological process
enzyme binding Blast molecular function
macromolecular complex Blast cellular component
protein homodimerization activity Orthology molecular function
sequence-specific DNA binding Orthology molecular function
transcription regulatory region DNA binding Orthology molecular function
positive regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
metal ion binding Orthology molecular function
protein heterodimerization activity Blast molecular function
signal transduction Orthology biological process
response to lipid Orthology biological process
signaling receptor activity Orthology molecular function
cellular response to organic substance Orthology biological process
small molecule binding Orthology molecular function
anion binding Orthology molecular function
cellular metabolic process Orthology biological process
organic substance metabolic process Orthology biological process
developmental process Orthology biological process
reproductive process Orthology biological process
response to organic substance Orthology biological process
anatomical structure formation involved in morphogenesis Orthology biological process
multicellular organism development Orthology biological process
regulation of gene expression Orthology biological process
cellular component organization Orthology biological process
protein transport Orthology biological process
regulation of signaling Orthology biological process
cell-cell signaling Orthology biological process
cell surface receptor signaling pathway Orthology biological process
intracellular non-membrane-bounded organelle Blast cellular component
nuclear lumen Blast cellular component
chromatin binding Blast molecular function
binding Blast molecular function
nuclear part Blast cellular component

GO (Orthology)

48 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
RNA polymerase II activating transcription factor binding Hs molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function
DNA binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function
steroid hormone receptor activity Hs molecular function
nuclear receptor activity Hs molecular function
receptor binding Hs molecular function
fatty acid binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
regulation of transcription from RNA polymerase II promoter Hs biological process
transcription from RNA polymerase II promoter Hs biological process
transcription initiation from RNA polymerase II promoter Hs biological process
ornithine metabolic process Hs biological process
lipid metabolic process Hs biological process
xenobiotic metabolic process Hs biological process
sex differentiation Hs biological process
blood coagulation Hs biological process
zinc ion binding Hs molecular function
negative regulation of cell proliferation Hs biological process
response to glucose Hs biological process
regulation of gastrulation Hs biological process
regulation of lipid metabolic process Hs biological process
signal transduction involved in regulation of gene expression Hs biological process
negative regulation of cell growth Hs biological process
intracellular receptor signaling pathway Hs biological process
glucose homeostasis Hs biological process
cholesterol homeostasis Hs biological process
protein homodimerization activity Hs molecular function
steroid hormone mediated signaling pathway Hs biological process
sequence-specific DNA binding Hs molecular function
transcription regulatory region DNA binding Hs molecular function
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
metal ion binding Hs molecular function
regulation of insulin secretion Hs biological process
lipid homeostasis Hs biological process
phospholipid homeostasis Hs biological process
SMAD protein signal transduction Hs biological process
triglyceride homeostasis Hs biological process

GO (Blast)

42 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nuclear chromatin Hs cellular component 275 3.11e-87
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function 275 3.11e-87
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function 513 2.38e-180
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 513 2.38e-180
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function 513 2.38e-180
RNA polymerase II activating transcription factor binding Hs molecular function 509 3.31e-178
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function 509 3.31e-178
retinoic acid binding Hs molecular function 275 3.11e-87
DNA binding Hs molecular function 513 2.38e-180
double-stranded DNA binding Hs molecular function 275 3.11e-87
transcription factor activity, sequence-specific DNA binding Hs molecular function 513 2.38e-180
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Hs molecular function 509 3.31e-178
steroid hormone receptor activity Hs molecular function 513 2.38e-180
retinoic acid receptor activity Hs molecular function 275 3.11e-87
transcription coactivator activity Hs molecular function 275 3.11e-87
nuclear receptor activity Hs molecular function 513 2.38e-180
9-cis retinoic acid receptor activity Hs molecular function 275 3.11e-87
receptor binding Hs molecular function 509 3.31e-178
fatty acid binding Hs molecular function 509 3.31e-178
protein binding Hs molecular function 509 3.31e-178
nucleus Hs cellular component 513 2.38e-180
nucleoplasm Hs cellular component 513 2.38e-180
cytoplasm Hs cellular component 509 3.31e-178
transcription factor binding Hs molecular function 275 3.11e-87
zinc ion binding Hs molecular function 513 2.38e-180
ligand-dependent nuclear receptor binding Hs molecular function 275 3.11e-87
enzyme binding Hs molecular function 275 3.11e-87
chromatin DNA binding Hs molecular function 275 3.11e-87
macromolecular complex Hs cellular component 275 3.11e-87
peptide binding Hs molecular function 275 3.11e-87
protein homodimerization activity Hs molecular function 509 3.31e-178
vitamin D receptor binding Hs molecular function 275 3.11e-87
receptor complex Hs cellular component 275 3.11e-87
sequence-specific DNA binding Hs molecular function 513 2.38e-180
transcription regulatory region DNA binding Hs molecular function 509 3.31e-178
retinoic acid-responsive element binding Hs molecular function 275 3.11e-87
metal ion binding Hs molecular function 513 2.38e-180
protein heterodimerization activity Hs molecular function 275 3.11e-87
DBD domain binding Hs molecular function 275 3.11e-87
LBD domain binding Hs molecular function 275 3.11e-87
vitamin D response element binding Hs molecular function 275 3.11e-87
RNA polymerase II transcription factor complex Hs cellular component 275 3.11e-87

GO (InterProScan)

8 results

GO Term Analysis Type e-value
DNA binding PRINTS molecular function 2.3E-25
transcription factor activity, sequence-specific DNA binding SMART molecular function 7.8E-38
steroid hormone receptor activity PRINTS molecular function 2.3E-25
nucleus SMART cellular component 7.8E-38
regulation of transcription, DNA-templated SMART biological process 3.1E-45
zinc ion binding SMART molecular function 7.8E-38
steroid hormone mediated signaling pathway SMART biological process 3.1E-45
sequence-specific DNA binding SMART molecular function 7.8E-38