Aniseed - Gene card

Gene Card

Best human hits

MKL1; MKL2; MYOCD

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00006140

Gene Model ID

KH2012:KH.C3.923

Location

KhC3:2366848..2377514

Transcript Models and Sequences

KH2012:KH.C3.923.v1.A.SL1-1

External Database Gene Card

External database links

No result

Collections

Gateway full ORF

2 results

Gene collection 1 (N. Satoh)

2 results

cicl060l06

Plate: R1CiGC15a22

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Regulatory Regions

1 results

myocardin 6166/6294 REG00000465 [ inactive_region ]

Gene Phylogeny

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Gene Annotations

InterPro

3 results

IPR Term	Analysis	Definition
RPEL_repeat	ProSiteProfiles	RPEL repeat
RPEL_repeat	SMART	RPEL repeat
SAP_dom_sf	Gene3D	SAP domain superfamily

GOSlim

56 results

GO Term	Annotation Origin	Type
negative regulation of transcription from RNA polymerase II promoter	Orthology	biological process
transcription regulatory region sequence-specific DNA binding	Orthology	molecular function
core promoter proximal region sequence-specific DNA binding	Orthology	molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	Orthology	molecular function
response to hypoxia	Orthology	biological process
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
transcription coactivator activity	Orthology	molecular function
actin binding	Orthology	molecular function
protein binding	Orthology	molecular function
nucleus	Orthology	cellular component
nucleoplasm	Orthology	cellular component
cytoplasm	Orthology	cellular component
cytosol	Orthology	cellular component
transcription, DNA-templated	Orthology	biological process
regulation of transcription, DNA-templated	Orthology	biological process
regulation of transcription from RNA polymerase II promoter	Orthology	biological process
transcription from RNA polymerase II promoter	Orthology	biological process
multicellular organism development	Orthology	biological process
heart development	Orthology	biological process
transcription factor binding	Orthology	molecular function
positive regulation of cell proliferation	Orthology	biological process
negative regulation of cell proliferation	Orthology	biological process
positive regulation of gene expression	Orthology	biological process
cell differentiation	Orthology	biological process
neuron projection development	Orthology	biological process
positive regulation of transcription, DNA-templated	Orthology	biological process
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
regulation of nucleic acid-templated transcription	Orthology	biological process
intracellular non-membrane-bounded organelle	Orthology	cellular component
nuclear lumen	Orthology	cellular component
blood vessel morphogenesis	Orthology	biological process
cell migration	Orthology	biological process
generation of neurons	Orthology	biological process
protein dephosphorylation	Orthology	biological process
enzyme regulator activity	Orthology	molecular function
enzyme binding	Orthology	molecular function
animal organ development	Orthology	biological process
negative regulation of apoptotic process	Orthology	biological process
organelle organization	Orthology	biological process
cell surface receptor signaling pathway	Orthology	biological process
positive regulation of signal transduction	Orthology	biological process
cellular response to organic substance	Orthology	biological process
brain development	Orthology	biological process
regulation of cellular metabolic process	Orthology	biological process
cellular protein modification process	Orthology	biological process
anatomical structure development	Orthology	biological process
endopeptidase activity	Orthology	molecular function
DNA binding	Orthology	molecular function
cell adhesion molecule binding	Orthology	molecular function
cell cycle	Orthology	biological process
regulation of catalytic activity	Orthology	biological process
molecular transducer activity	Orthology	molecular function
protein serine/threonine kinase activity	Orthology	molecular function
system development	Orthology	biological process
reproductive process	Orthology	biological process
negative regulation of signal transduction	Orthology	biological process

GO (Orthology)

66 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
nuclear chromatin	Hs	cellular component
transcription regulatory region sequence-specific DNA binding	Hs	molecular function
core promoter proximal region sequence-specific DNA binding	Hs	molecular function
core promoter sequence-specific DNA binding	Hs	molecular function
transcription factor activity, RNA polymerase II transcription factor binding	Hs	molecular function
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function
RNA polymerase II transcription coactivator activity	Hs	molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	Hs	molecular function
vasculogenesis	Hs	biological process
response to hypoxia	Hs	biological process
neuron migration	Hs	biological process
cardiac ventricle development	Hs	biological process
transcription factor activity, sequence-specific DNA binding	Hs	molecular function
transcription coactivator activity	Hs	molecular function
actin binding	Hs	molecular function
actin monomer binding	Hs	molecular function
protein phosphatase inhibitor activity	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
regulation of transcription from RNA polymerase II promoter	Hs	biological process
transcription from RNA polymerase II promoter	Hs	biological process
multicellular organism development	Hs	biological process
heart development	Hs	biological process
muscle organ development	Hs	biological process
transcription factor binding	Hs	molecular function
positive regulation of cell proliferation	Hs	biological process
negative regulation of cell proliferation	Hs	biological process
positive regulation of gene expression	Hs	biological process
negative regulation of cardiac muscle cell apoptotic process	Hs	biological process
positive regulation of transcription via serum response element binding	Hs	biological process
actin cytoskeleton organization	Hs	biological process
cell differentiation	Hs	biological process
positive regulation of transforming growth factor beta receptor signaling pathway	Hs	biological process
forebrain development	Hs	biological process
neuron projection development	Hs	biological process
negative regulation of phosphoprotein phosphatase activity	Hs	biological process
histone acetyltransferase binding	Hs	molecular function
cardiocyte differentiation	Hs	biological process
regulation of histone acetylation	Hs	biological process
muscle cell differentiation	Hs	biological process
histone deacetylase binding	Hs	molecular function
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Hs	biological process
positive regulation of DNA binding	Hs	biological process
leucine zipper domain binding	Hs	molecular function
cadherin binding	Hs	molecular function
regulation of myoblast differentiation	Hs	biological process
negative regulation of cyclin-dependent protein serine/threonine kinase activity	Hs	biological process
positive regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
positive regulation of smooth muscle contraction	Hs	biological process
digestive tract development	Hs	biological process
positive regulation of sequence-specific DNA binding transcription factor activity	Hs	biological process
smooth muscle cell differentiation	Hs	biological process
cardiac muscle cell differentiation	Hs	biological process
ventricular cardiac muscle cell differentiation	Hs	biological process
uterus development	Hs	biological process
R-SMAD binding	Hs	molecular function
regulation of nucleic acid-templated transcription	Hs	biological process
positive regulation of cardiac muscle cell differentiation	Hs	biological process
negative regulation of apoptotic signaling pathway	Hs	biological process

GO (Blast)

24 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nuclear chromatin	Hs	cellular component	144	4.64e-35
transcription regulatory region sequence-specific DNA binding	Hs	molecular function	171	9.35e-44
core promoter proximal region sequence-specific DNA binding	Hs	molecular function	144	4.64e-35
core promoter sequence-specific DNA binding	Hs	molecular function	144	4.64e-35
transcription factor activity, RNA polymerase II transcription factor binding	Hs	molecular function	144	4.64e-35
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function	144	4.64e-35
RNA polymerase II transcription coactivator activity	Hs	molecular function	183	1.62e-47
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	Hs	molecular function	144	4.64e-35
transcription factor activity, sequence-specific DNA binding	Hs	molecular function	171	9.35e-44
transcription coactivator activity	Hs	molecular function	183	1.62e-47
actin binding	Hs	molecular function	183	1.62e-47
actin monomer binding	Hs	molecular function	171	9.35e-44
protein phosphatase inhibitor activity	Hs	molecular function	183	1.62e-47
protein binding	Hs	molecular function	183	1.62e-47
nucleus	Hs	cellular component	183	1.62e-47
nucleoplasm	Hs	cellular component	171	9.35e-44
cytoplasm	Hs	cellular component	171	9.35e-44
cytosol	Hs	cellular component	171	9.35e-44
transcription factor binding	Hs	molecular function	144	4.64e-35
histone acetyltransferase binding	Hs	molecular function	144	4.64e-35
histone deacetylase binding	Hs	molecular function	144	4.64e-35
leucine zipper domain binding	Hs	molecular function	171	9.35e-44
cadherin binding	Hs	molecular function	183	1.62e-47
R-SMAD binding	Hs	molecular function	144	4.64e-35

GO (InterProScan)