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GENE CARD

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Gene Card

Best human hits

BMP2; BMP4; BMP7

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00006191

Gene Model ID

KH2012:KH.C4.125

Location

KhC4:1880675..1900733

Transcript Models and Sequences

  KH2012:KH.C4.125.v1.A.SL5-1
KH2012:KH.C4.125.v1.R.ND2-1
KH2012:KH.C4.125.v2.A.SL4-1
KH2012:KH.C4.125.v3.A.SL1-1
KH2012:KH.C4.125.v4.A.ND3-1

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000019816
NCBI Reference Sequence XM_018811396.1
Collections

Gateway full ORF

2 results

cien53254

Plate: VES78_N14

cien209101

Plate: VES102_G18

Gene collection 1 (N. Satoh)

1 result

cicl060n01

Plate: R1CiGC15c08

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

8 results

IPR Term Analysis Definition
TGF-beta-rel PANTHER Transforming growth factor-beta-related
TGF-b_C Pfam Transforming growth factor-beta, C-terminal
TGF-b_C SMART Transforming growth factor-beta, C-terminal
TGF-b_propeptide Pfam TGF-beta, propeptide
Cystine-knot_cytokine SUPERFAMILY Cystine-knot cytokine
TGF-b_C ProSiteProfiles Transforming growth factor-beta, C-terminal
TGFb_CS ProSitePatterns Transforming growth factor beta, conserved site
Cystine-knot_cytokine Gene3D Cystine-knot cytokine

GOSlim

86 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
angiogenesis Orthology biological process
blood vessel development Orthology biological process
response to hypoxia Orthology biological process
vasculature development Orthology biological process
receptor binding Orthology molecular function
protein binding Orthology molecular function
extracellular region Orthology cellular component
extracellular space Orthology cellular component
endoplasmic reticulum lumen Orthology cellular component
regulation of transcription, DNA-templated Orthology biological process
protein phosphorylation Orthology biological process
Notch signaling pathway Orthology biological process
cell-cell signaling Orthology biological process
multicellular organism development Orthology biological process
heart development Orthology biological process
positive regulation of cell proliferation Orthology biological process
negative regulation of cell proliferation Orthology biological process
cell surface Orthology cellular component
regulation of gene expression Orthology biological process
positive regulation of gene expression Orthology biological process
negative regulation of gene expression Orthology biological process
positive regulation of cell death Orthology biological process
cell differentiation Orthology biological process
positive regulation of Wnt signaling pathway Orthology biological process
vesicle Blast cellular component
positive regulation of apoptotic process Orthology biological process
negative regulation of apoptotic process Orthology biological process
intracellular membrane-bounded organelle Orthology cellular component
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
protein heterodimerization activity Orthology molecular function
cell development Orthology biological process
anatomical structure formation involved in morphogenesis Orthology biological process
oxidation-reduction process Orthology biological process
negative regulation of cell death Orthology biological process
negative regulation of canonical Wnt signaling pathway Orthology biological process
positive regulation of catalytic activity Orthology biological process
intracellular signal transduction Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
positive regulation of signal transduction Orthology biological process
system development Orthology biological process
animal organ development Orthology biological process
anatomical structure morphogenesis Orthology biological process
nervous system development Orthology biological process
cell proliferation Orthology biological process
immune system process Orthology biological process
negative regulation of Wnt signaling pathway Orthology biological process
catalytic activity Orthology molecular function
molecular function regulator Orthology molecular function
regulation of signal transduction Orthology biological process
signaling receptor activity Orthology molecular function
protein metabolic process Orthology biological process
defense response Orthology biological process
cell surface receptor signaling pathway Orthology biological process
gamete generation Orthology biological process
anatomical structure development Orthology biological process
anion binding Orthology molecular function
carbohydrate derivative binding Orthology molecular function
regulation of molecular function Orthology biological process
dephosphorylation Orthology biological process
hydrolase activity Orthology molecular function
enzyme binding Orthology molecular function
enzyme activator activity Orthology molecular function
brain development Orthology biological process
cell migration Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
cellular response to organic substance Orthology biological process
protein localization to organelle Orthology biological process
chemotaxis Orthology biological process
intracellular protein transport Orthology biological process
establishment of protein localization to organelle Orthology biological process
phosphorylation Orthology biological process
signal transduction Orthology biological process
response to lipid Orthology biological process
regulation of catalytic activity Orthology biological process
negative regulation of signal transduction Orthology biological process
cellular protein modification process Orthology biological process
neuron differentiation Orthology biological process
cell cycle Orthology biological process
blood vessel morphogenesis Orthology biological process
integral component of plasma membrane Orthology cellular component
macromolecular complex Orthology cellular component
cellular response to stress Orthology biological process
extracellular region part Blast cellular component

GO (Orthology)

163 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
activation of MAPKK activity Hs biological process
activation of MAPK activity Hs biological process
skeletal system development Hs biological process
ossification Hs biological process
angiogenesis Hs biological process
blood vessel development Hs biological process
osteoblast differentiation Hs biological process
ureteric bud development Hs biological process
branching involved in ureteric bud morphogenesis Hs biological process
response to hypoxia Hs biological process
mesoderm formation Hs biological process
organ induction Hs biological process
kidney development Hs biological process
epithelial to mesenchymal transition Hs biological process
neural tube closure Hs biological process
positive regulation of protein phosphorylation Hs biological process
positive regulation of endothelial cell proliferation Hs biological process
vasculature development Hs biological process
endochondral ossification Hs biological process
blood vessel endothelial cell proliferation involved in sprouting angiogenesis Hs biological process
chondrocyte differentiation Hs biological process
hematopoietic progenitor cell differentiation Hs biological process
lymphoid progenitor cell differentiation Hs biological process
renal system process Hs biological process
outflow tract morphogenesis Hs biological process
atrioventricular valve morphogenesis Hs biological process
endocardial cushion development Hs biological process
endocardial cushion morphogenesis Hs biological process
negative regulation of Wnt signaling pathway involved in heart development Hs biological process
type B pancreatic cell development Hs biological process
retinol dehydrogenase activity Hs molecular function
receptor binding Hs molecular function
cytokine activity Hs molecular function
transforming growth factor beta receptor binding Hs molecular function
protein binding Hs molecular function
extracellular region Hs cellular component
proteinaceous extracellular matrix Hs cellular component
extracellular space Hs cellular component
endoplasmic reticulum lumen Hs cellular component
proteoglycan metabolic process Hs biological process
regulation of transcription, DNA-templated Hs biological process
protein phosphorylation Hs biological process
inflammatory response Hs biological process
Notch signaling pathway Hs biological process
smoothened signaling pathway Hs biological process
cell-cell signaling Hs biological process
multicellular organism development Hs biological process
germ cell development Hs biological process
endoderm development Hs biological process
mesodermal cell fate determination Hs biological process
heart development Hs biological process
growth factor activity Hs molecular function
heparin binding Hs molecular function
positive regulation of cell proliferation Hs biological process
negative regulation of cell proliferation Hs biological process
post-embryonic development Hs biological process
animal organ morphogenesis Hs biological process
tissue development Hs biological process
anterior/posterior axis specification Hs biological process
cell surface Hs cellular component
specification of animal organ position Hs biological process
regulation of gene expression Hs biological process
regulation of receptor activity Hs biological process
positive regulation of gene expression Hs biological process
negative regulation of gene expression Hs biological process
positive regulation of epithelial to mesenchymal transition Hs biological process
positive regulation of pathway-restricted SMAD protein phosphorylation Hs biological process
positive regulation of cell death Hs biological process
phosphatase activator activity Hs molecular function
telencephalon development Hs biological process
pituitary gland development Hs biological process
cell differentiation Hs biological process
positive regulation of Wnt signaling pathway Hs biological process
erythrocyte differentiation Hs biological process
monocyte differentiation Hs biological process
macrophage differentiation Hs biological process
bone mineralization Hs biological process
lung development Hs biological process
embryonic limb morphogenesis Hs biological process
positive regulation of cell migration Hs biological process
positive regulation of bone mineralization Hs biological process
BMP signaling pathway Hs biological process
positive regulation of BMP signaling pathway Hs biological process
forebrain development Hs biological process
protein destabilization Hs biological process
positive regulation of protein binding Hs biological process
protein localization to nucleus Hs biological process
cardiocyte differentiation Hs biological process
embryonic heart tube anterior/posterior pattern specification Hs biological process
embryonic hindlimb morphogenesis Hs biological process
co-receptor binding Hs molecular function
chemoattractant activity Hs molecular function
regulation of protein import into nucleus Hs biological process
negative regulation of phosphorylation Hs biological process
odontogenesis Hs biological process
camera-type eye development Hs biological process
positive regulation of apoptotic process Hs biological process
negative regulation of apoptotic process Hs biological process
intracellular membrane-bounded organelle Hs cellular component
steroid hormone mediated signaling pathway Hs biological process
negative regulation of MAP kinase activity Hs biological process
positive regulation of MAPK cascade Hs biological process
negative regulation of insulin-like growth factor receptor signaling pathway Hs biological process
post-translational protein modification Hs biological process
cell fate commitment Hs biological process
regulation of cell differentiation Hs biological process
positive regulation of cell differentiation Hs biological process
positive regulation of fat cell differentiation Hs biological process
positive regulation of endothelial cell differentiation Hs biological process
positive regulation of neuron differentiation Hs biological process
positive regulation of osteoblast differentiation Hs biological process
negative regulation of cell cycle Hs biological process
negative regulation of mitotic nuclear division Hs biological process
negative regulation of striated muscle tissue development Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
SMAD binding Hs molecular function
protein heterodimerization activity Hs molecular function
mesodermal cell differentiation Hs biological process
cell development Hs biological process
camera-type eye morphogenesis Hs biological process
embryonic morphogenesis Hs biological process
anatomical structure formation involved in morphogenesis Hs biological process
neuron fate commitment Hs biological process
embryonic cranial skeleton morphogenesis Hs biological process
embryonic skeletal system development Hs biological process
smooth muscle tissue development Hs biological process
branching morphogenesis of an epithelial tube Hs biological process
inner ear development Hs biological process
positive regulation of epithelial cell proliferation Hs biological process
negative regulation of epithelial cell proliferation Hs biological process
positive chemotaxis Hs biological process
smooth muscle cell differentiation Hs biological process
cartilage development Hs biological process
cardiac muscle cell differentiation Hs biological process
cardiac muscle tissue morphogenesis Hs biological process
oxidation-reduction process Hs biological process
inner ear receptor cell differentiation Hs biological process
embryonic skeletal joint morphogenesis Hs biological process
bone development Hs biological process
cranial suture morphogenesis Hs biological process
pathway-restricted SMAD protein phosphorylation Hs biological process
SMAD protein signal transduction Hs biological process
epithelium development Hs biological process
trachea development Hs biological process
negative regulation of cell death Hs biological process
coronary vasculature development Hs biological process
regulation of cartilage development Hs biological process
positive regulation of cartilage development Hs biological process
BMP signaling pathway involved in heart development Hs biological process
pharyngeal arch artery morphogenesis Hs biological process
positive regulation of ERK1 and ERK2 cascade Hs biological process
BMP receptor binding Hs molecular function
BMP receptor complex Hs cellular component
cellular response to organic cyclic compound Hs biological process
renal system development Hs biological process
glomerular visceral epithelial cell development Hs biological process
glomerular capillary formation Hs biological process
negative regulation of canonical Wnt signaling pathway Hs biological process
positive regulation of p38MAPK cascade Hs biological process
negative regulation of extrinsic apoptotic signaling pathway Hs biological process

GO (Blast)

22 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
retinol dehydrogenase activity Hs molecular function 359 7.96e-122
receptor binding Hs molecular function 359 7.96e-122
cytokine activity Hs molecular function 359 7.96e-122
transforming growth factor beta receptor binding Hs molecular function 359 7.96e-122
protein binding Hs molecular function 359 7.96e-122
extracellular region Hs cellular component 359 7.96e-122
proteinaceous extracellular matrix Hs cellular component 338 1.72e-113
extracellular space Hs cellular component 359 7.96e-122
endoplasmic reticulum lumen Hs cellular component 338 1.72e-113
growth factor activity Hs molecular function 359 7.96e-122
heparin binding Hs molecular function 338 1.72e-113
cell surface Hs cellular component 359 7.96e-122
phosphatase activator activity Hs molecular function 359 7.96e-122
extracellular matrix Hs cellular component 181 2.70e-52
vesicle Hs cellular component 181 2.70e-52
co-receptor binding Hs molecular function 359 7.96e-122
chemoattractant activity Hs molecular function 338 1.72e-113
intracellular membrane-bounded organelle Hs cellular component 359 7.96e-122
SMAD binding Hs molecular function 359 7.96e-122
protein heterodimerization activity Hs molecular function 359 7.96e-122
BMP receptor binding Hs molecular function 359 7.96e-122
BMP receptor complex Hs cellular component 359 7.96e-122

GO (InterProScan)

1 result

GO Term Analysis Type e-value
growth factor activity SMART molecular function 1.3E-62

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