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Gene Card

Best human hits

USP25; USP28; USP48

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00006368

Gene Model ID

KH2012:KH.C4.29

Location

KhC4:3220339..3232078

Transcript Models and Sequences

  KH2012:KH.C4.29.v1.A.SL2-1
KH2012:KH.C4.29.v1.A.SL5-1
KH2012:KH.C4.29.v2.A.SL1-1
KH2012:KH.C4.29.v2.A.SL3-1
KH2012:KH.C4.29.v2.A.SL4-1
KH2012:KH.C4.29.v3.A.SL1-1
KH2012:KH.C4.29.v3.A.SL3-1
KH2012:KH.C4.29.v3.A.SL4-1
KH2012:KH.C4.29.v4.A.SL2-1
KH2012:KH.C4.29.v4.A.SL5-1

External Database Gene Card

External database links

5 results

Database Gene ID
ENSEMBL ENSCING00000020732
NCBI Reference Sequence XM_002123334.3
NCBI Reference Sequence XM_018811551.1
NCBI Reference Sequence XM_018811553.1
NCBI Reference Sequence XM_018811554.1
Collections

Gateway full ORF

3 results

cien87183

Plate: VES84_A02

cien140787

Plate: VES92_A07

cien160876

Plate: VES95_F04

Gene collection 1 (N. Satoh)

3 results

cieg054j18

Plate: R1CiGC24a12

cieg074g09

Plate: R1CiGC40a18

citb082j02

Plate: R1CiGC46d15

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

5 results

IPR Term Analysis Definition
Peptidase_C19_UCH Pfam Peptidase C19, ubiquitin carboxyl-terminal hydrolase
UIM_dom SMART Ubiquitin interacting motif
USP_CS ProSitePatterns Ubiquitin specific protease, conserved site
USP_dom ProSiteProfiles Ubiquitin specific protease domain
UIM_dom ProSiteProfiles Ubiquitin interacting motif

GOSlim

25 results

GO Term Annotation Origin Type
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
mitochondrion Blast cellular component
endoplasmic reticulum Orthology cellular component
cytosol Orthology cellular component
DNA repair Orthology biological process
cellular protein modification process Orthology biological process
proteolysis Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
peptidase activity Orthology molecular function
cell proliferation Orthology biological process
nuclear body Orthology cellular component
hydrolase activity Orthology molecular function
ubiquitin protein ligase binding Orthology molecular function
macromolecular complex Orthology cellular component
cell cycle Orthology biological process
peptidase activity, acting on L-amino acid peptides Orthology molecular function
small GTPase mediated signal transduction Orthology biological process
intracellular signal transduction Orthology biological process
apoptotic process Orthology biological process
enzyme binding Orthology molecular function
cellular response to stress Orthology biological process
response to organic substance Orthology biological process

GO (Orthology)

32 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
DNA damage checkpoint Hs biological process
thiol-dependent ubiquitin-specific protease activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
endoplasmic reticulum Hs cellular component
cytosol Hs cellular component
DNA repair Hs biological process
cellular protein modification process Hs biological process
proteolysis Hs biological process
ubiquitin-dependent protein catabolic process Hs biological process
cellular response to DNA damage stimulus Hs biological process
Ras protein signal transduction Hs biological process
peptidase activity Hs molecular function
cysteine-type peptidase activity Hs molecular function
cell proliferation Hs biological process
response to ionizing radiation Hs biological process
protein deubiquitination Hs biological process
nuclear body Hs cellular component
hydrolase activity Hs molecular function
ubiquitin protein ligase binding Hs molecular function
regulation of protein stability Hs biological process
macromolecular complex Hs cellular component
cellular response to UV Hs biological process
thiol-dependent ubiquitinyl hydrolase activity Hs molecular function
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Hs biological process
ubiquitin binding Hs molecular function
ATPase binding Hs molecular function
protein K63-linked deubiquitination Hs biological process
protein K48-linked deubiquitination Hs biological process
ubiquitin-specific protease activity involved in negative regulation of ERAD pathway Hs molecular function

GO (Blast)

18 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
thiol-dependent ubiquitin-specific protease activity Hs molecular function 534 1.11e-171
protein binding Hs molecular function 534 1.11e-171
nucleus Hs cellular component 534 1.11e-171
nucleoplasm Hs cellular component 166 1.43e-41
cytoplasm Hs cellular component 534 1.11e-171
mitochondrion Hs cellular component 67.0 4.92e-11
endoplasmic reticulum Hs cellular component 534 1.11e-171
cytosol Hs cellular component 534 1.11e-171
peptidase activity Hs molecular function 534 1.11e-171
cysteine-type peptidase activity Hs molecular function 534 1.11e-171
nuclear body Hs cellular component 166 1.43e-41
hydrolase activity Hs molecular function 534 1.11e-171
ubiquitin protein ligase binding Hs molecular function 534 1.11e-171
macromolecular complex Hs cellular component 166 1.43e-41
thiol-dependent ubiquitinyl hydrolase activity Hs molecular function 534 1.11e-171
ubiquitin binding Hs molecular function 534 1.11e-171
ATPase binding Hs molecular function 534 1.11e-171
ubiquitin-specific protease activity involved in negative regulation of ERAD pathway Hs molecular function 534 1.11e-171

GO (InterProScan)

3 results

GO Term Analysis Type e-value
ubiquitin-dependent protein catabolic process ProSitePatterns biological process
protein deubiquitination Pfam biological process 3.0E-47
thiol-dependent ubiquitinyl hydrolase activity Pfam molecular function 3.0E-47

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