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Gene Card

Best human hits

THBS1; THBS2; THBS4

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00006442

Gene Model ID

KH2012:KH.C4.358

Location

KhC4:2422238..2436258

Transcript Models and Sequences

  KH2012:KH.C4.358.v1.A.SL2-1
KH2012:KH.C4.358.v1.R.ND1-1

External Database Gene Card

External database links

3 results

Database Gene ID
ENSEMBL ENSCING00000007650
NCBI Reference Sequence NM_001033843.1
NCBI Reference Sequence XM_018811393.1
Collections

Gateway full ORF

2 results

cima822554

Plate: VES60_K08

cima886520

Plate: VES69_E24

Gene collection 1 (N. Satoh)

1 result

ciad010b04

Plate: R1CiGC02a09

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

21 results

IPR Term Analysis Definition
Thrombospondin_3_rpt ProSiteProfiles Thrombospondin, type 3 repeat
Laminin_G SMART Laminin G domain
Thrombospondin PANTHER Thrombospondin
ConA-like_dom_sf SUPERFAMILY Concanavalin A-like lectin/glucanase domain superfamily
Thrombospondin_C Pfam Thrombospondin, C-terminal
TSP_type-3_rpt SUPERFAMILY TSP type-3 repeat
VWF_dom ProSitePatterns VWFC domain
TSP1_rpt ProSiteProfiles Thrombospondin type-1 (TSP1) repeat
TSP1_rpt_sf SUPERFAMILY Thrombospondin type-1 (TSP1) repeat superfamily
TSP1_rpt Pfam Thrombospondin type-1 (TSP1) repeat
VWF_dom Pfam VWFC domain
Thrombospondin_C ProSiteProfiles Thrombospondin, C-terminal
EGF-like_dom ProSiteProfiles EGF-like domain
TSP1_rpt SMART Thrombospondin type-1 (TSP1) repeat
EGF-like_Ca-bd_dom SMART EGF-like calcium-binding domain
VWF_dom ProSiteProfiles VWFC domain
TSP_type-3_rpt Gene3D TSP type-3 repeat
TSP1_rpt_sf Gene3D Thrombospondin type-1 (TSP1) repeat superfamily
EGF-like_dom SMART EGF-like domain
VWF_dom SMART VWFC domain
Thrombospondin_3-like_rpt Pfam Thrombospondin, type 3-like repeat

GOSlim

57 results

GO Term Annotation Origin Type
response to hypoxia Orthology biological process
integrin binding Orthology molecular function
calcium ion binding Orthology molecular function
protein binding Orthology molecular function
extracellular region Orthology cellular component
extracellular space Orthology cellular component
cytoplasm Orthology cellular component
endoplasmic reticulum Orthology cellular component
endoplasmic reticulum lumen Orthology cellular component
immune response Orthology biological process
cell adhesion Orthology biological process
positive regulation of cell proliferation Orthology biological process
cell surface Orthology cellular component
cell migration Orthology biological process
extracellular matrix organization Orthology biological process
identical protein binding Orthology molecular function
negative regulation of apoptotic process Orthology biological process
extracellular exosome Orthology cellular component
positive regulation of catalytic activity Orthology biological process
intracellular signal transduction Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
positive regulation of signal transduction Orthology biological process
anion binding Orthology molecular function
angiogenesis Orthology biological process
membrane organization Orthology biological process
organelle organization Orthology biological process
macromolecular complex Orthology cellular component
extracellular region part Orthology cellular component
defense response Orthology biological process
response to stress Orthology biological process
response to organic substance Orthology biological process
carbohydrate derivative binding Orthology molecular function
plasma membrane part Orthology cellular component
negative regulation of signal transduction Orthology biological process
negative regulation of gene expression Orthology biological process
proteolysis Orthology biological process
cellular protein modification process Orthology biological process
cytoplasmic vesicle Orthology cellular component
endomembrane system Orthology cellular component
macromolecular complex binding Orthology molecular function
blood coagulation Orthology biological process
cell surface receptor signaling pathway Orthology biological process
cellular response to organic substance Orthology biological process
intracellular organelle part Orthology cellular component
intracellular organelle lumen Orthology cellular component
response to lipid Orthology biological process
cellular response to stress Orthology biological process
phosphorylation Orthology biological process
endopeptidase activity Orthology molecular function
positive regulation of gene expression Orthology biological process
binding Orthology molecular function
chemotaxis Orthology biological process
nervous system development Orthology biological process
receptor binding Blast molecular function
molecular function regulator Blast molecular function
regulation of signal transduction Blast biological process
signaling receptor activity Blast molecular function

GO (Orthology)

75 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
activation of MAPK activity Hs biological process
response to hypoxia Hs biological process
phosphatidylserine binding Hs molecular function
fibronectin binding Hs molecular function
sprouting angiogenesis Hs biological process
platelet degranulation Hs biological process
integrin binding Hs molecular function
calcium ion binding Hs molecular function
protein binding Hs molecular function
extracellular region Hs cellular component
fibrinogen complex Hs cellular component
proteinaceous extracellular matrix Hs cellular component
basement membrane Hs cellular component
extracellular space Hs cellular component
cytoplasm Hs cellular component
endoplasmic reticulum Hs cellular component
endoplasmic reticulum lumen Hs cellular component
inflammatory response Hs biological process
immune response Hs biological process
response to unfolded protein Hs biological process
cell cycle arrest Hs biological process
cell adhesion Hs biological process
heparin binding Hs molecular function
positive regulation of cell proliferation Hs biological process
response to mechanical stimulus Hs biological process
response to glucose Hs biological process
external side of plasma membrane Hs cellular component
cell surface Hs cellular component
negative regulation of cGMP-mediated signaling Hs biological process
negative regulation of plasminogen activation Hs biological process
cell migration Hs biological process
negative regulation of angiogenesis Hs biological process
sarcoplasmic reticulum Hs cellular component
fibroblast growth factor binding Hs molecular function
peptide cross-linking Hs biological process
secretory granule Hs cellular component
low-density lipoprotein particle binding Hs molecular function
positive regulation of blood coagulation Hs biological process
extracellular matrix organization Hs biological process
positive regulation of cell migration Hs biological process
positive regulation of transforming growth factor beta receptor signaling pathway Hs biological process
extracellular matrix Hs cellular component
platelet alpha granule Hs cellular component
platelet alpha granule lumen Hs cellular component
response to magnesium ion Hs biological process
response to progesterone Hs biological process
cellular response to heat Hs biological process
response to endoplasmic reticulum stress Hs biological process
protein O-linked fucosylation Hs biological process
negative regulation of fibroblast growth factor receptor signaling pathway Hs biological process
positive regulation of phosphorylation Hs biological process
response to drug Hs biological process
identical protein binding Hs molecular function
negative regulation of apoptotic process Hs biological process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
laminin binding Hs molecular function
proteoglycan binding Hs molecular function
negative regulation of blood vessel endothelial cell migration Hs biological process
engulfment of apoptotic cell Hs biological process
positive regulation of translation Hs biological process
positive regulation of angiogenesis Hs biological process
behavioral response to pain Hs biological process
transforming growth factor beta binding Hs molecular function
extracellular matrix binding Hs molecular function
positive regulation of chemotaxis Hs biological process
response to calcium ion Hs biological process
negative regulation of focal adhesion assembly Hs biological process
positive regulation of protein kinase B signaling Hs biological process
positive regulation of synapse assembly Hs biological process
fibrinogen binding Hs molecular function
collagen V binding Hs molecular function
extracellular exosome Hs cellular component
cellular response to tumor necrosis factor Hs biological process
positive regulation of reactive oxygen species metabolic process Hs biological process
negative regulation of extrinsic apoptotic signaling pathway Hs biological process

GO (Blast)

32 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
phosphatidylserine binding Hs molecular function 1095 0.0
fibronectin binding Hs molecular function 1095 0.0
integrin binding Hs molecular function 1095 0.0
calcium ion binding Hs molecular function 1095 0.0
protein binding Hs molecular function 1095 0.0
extracellular region Hs cellular component 1095 0.0
fibrinogen complex Hs cellular component 1095 0.0
proteinaceous extracellular matrix Hs cellular component 1079 0.0
basement membrane Hs cellular component 1079 0.0
extracellular space Hs cellular component 1095 0.0
cytoplasm Hs cellular component 1095 0.0
endoplasmic reticulum Hs cellular component 1095 0.0
endoplasmic reticulum lumen Hs cellular component 1095 0.0
growth factor activity Hs molecular function 589 0.0
heparin binding Hs molecular function 1095 0.0
external side of plasma membrane Hs cellular component 1095 0.0
cell surface Hs cellular component 1095 0.0
sarcoplasmic reticulum Hs cellular component 1095 0.0
fibroblast growth factor binding Hs molecular function 1095 0.0
secretory granule Hs cellular component 1095 0.0
low-density lipoprotein particle binding Hs molecular function 1095 0.0
extracellular matrix Hs cellular component 1095 0.0
platelet alpha granule Hs cellular component 1095 0.0
platelet alpha granule lumen Hs cellular component 1095 0.0
identical protein binding Hs molecular function 1095 0.0
laminin binding Hs molecular function 1095 0.0
proteoglycan binding Hs molecular function 1095 0.0
transforming growth factor beta binding Hs molecular function 1095 0.0
extracellular matrix binding Hs molecular function 1095 0.0
fibrinogen binding Hs molecular function 1095 0.0
collagen V binding Hs molecular function 1095 0.0
extracellular exosome Hs cellular component 1095 0.0

GO (InterProScan)

6 results

GO Term Analysis Type e-value
calcium ion binding Pfam molecular function 5.6E-92
protein binding Pfam molecular function 1.2E-7
extracellular region Pfam cellular component 5.6E-92
cell adhesion Pfam biological process 5.6E-92
extracellular matrix organization PANTHER biological process 0.0
extracellular matrix PANTHER cellular component 0.0

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