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GENE CARD

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Gene Card

Best human hits

KMT2A; SETD1A; SETD1B

Unique Gene ID

Cirobu.g00006948

Gene Model ID

KH2012:KH.C4.91

Location

KhC4:440457..457120

Collections

Gateway full ORF

2 results

cien107675

Plate: VES87_B03

cien145911

Plate: VES93_M01

Gene collection 1 (N. Satoh)

3 results

cieg015o10

Plate: R1CiGC17p06

cieg026p08

Plate: R1CiGC19j22

cign044g10

Plate: R1CiGC42o16

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

14 results

IPR Term Analysis Definition
RBD_domain_sf SUPERFAMILY RNA-binding domain superfamily
SET_dom ProSiteProfiles SET domain
RRM_dom Pfam RNA recognition motif domain
Post-SET_dom SMART Post-SET domain
SETD1B PANTHER Histone-lysine N-methyltransferase SETD1B
COMPASS_Set1_N-SET SMART COMPASS complex Set1 subunit, N-SET domain
Post-SET_dom ProSiteProfiles Post-SET domain
Nucleotide-bd_a/b_plait_sf Gene3D Nucleotide-binding alpha-beta plait domain superfamily
RRM_dom ProSiteProfiles RNA recognition motif domain
COMPASS_Set1_N-SET Pfam COMPASS complex Set1 subunit, N-SET domain
SET_dom SMART SET domain
RRM_dom SMART RNA recognition motif domain
SET_dom Pfam SET domain
SETD1-like PANTHER Histone-lysine N-methyltransferase SETD1-like

GOSlim

36 results

GO Term Annotation Origin Type
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
nucleic acid binding Blast molecular function
DNA binding Orthology molecular function
chromatin binding Blast molecular function
transcription factor activity, sequence-specific DNA binding Blast molecular function
RNA binding Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytosol Blast cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
transcription factor binding Blast molecular function
zinc ion binding Blast molecular function
nuclear speck Blast cellular component
transferase activity Orthology molecular function
identical protein binding Blast molecular function
protein homodimerization activity Blast molecular function
transcription regulatory region DNA binding Orthology molecular function
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
metal ion binding Orthology molecular function
positive regulation of cell proliferation Orthology biological process
organelle organization Orthology biological process
metabolic process Orthology biological process
cellular protein modification process Orthology biological process
nucleoplasm part Orthology cellular component
macromolecular complex Orthology cellular component
cell development Orthology biological process
gamete generation Orthology biological process
negative regulation of transcription, DNA-templated Orthology biological process
response to stimulus Orthology biological process
intracellular non-membrane-bounded organelle Blast cellular component
nuclear lumen Blast cellular component
transcription regulatory region sequence-specific DNA binding Blast molecular function
sequence-specific double-stranded DNA binding Blast molecular function
sequence-specific DNA binding Blast molecular function

GO (Orthology)

27 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
DNA binding Hs molecular function
RNA binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
chromatin organization Hs biological process
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
methyltransferase activity Hs molecular function
transferase activity Hs molecular function
histone-lysine N-methyltransferase activity Hs molecular function
methylation Hs biological process
histone lysine methylation Hs biological process
histone methyltransferase complex Hs cellular component
histone methyltransferase activity (H3-K4 specific) Hs molecular function
transcription regulatory region DNA binding Hs molecular function
positive regulation of transcription from RNA polymerase II promoter Hs biological process
metal ion binding Hs molecular function
histone H3-K4 methylation Hs biological process
oocyte growth Hs biological process
chromatin silencing Hs biological process
positive regulation of cell proliferation Hs biological process
transferase activity, transferring acyl groups Hs molecular function
response to estrogen Hs biological process
MLL3/4 complex Hs cellular component
oogenesis Hs biological process

GO (Blast)

31 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nuclear chromatin Hs cellular component 309 5.72e-85
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 169 1.22e-41
core promoter sequence-specific DNA binding Hs molecular function 169 1.22e-41
nucleic acid binding Hs molecular function 315 1.31e-86
DNA binding Hs molecular function 169 1.22e-41
AT DNA binding Hs molecular function 169 1.22e-41
chromatin binding Hs molecular function 169 1.22e-41
transcription factor activity, sequence-specific DNA binding Hs molecular function 169 1.22e-41
RNA binding Hs molecular function 315 1.31e-86
protein binding Hs molecular function 315 1.31e-86
nucleus Hs cellular component 315 1.31e-86
nucleoplasm Hs cellular component 315 1.31e-86
chromosome Hs cellular component 315 1.31e-86
cytosol Hs cellular component 315 1.31e-86
beta-catenin binding Hs molecular function 309 5.72e-85
transcription factor binding Hs molecular function 309 5.72e-85
methyltransferase activity Hs molecular function 315 1.31e-86
zinc ion binding Hs molecular function 169 1.22e-41
nuclear speck Hs cellular component 315 1.31e-86
transferase activity Hs molecular function 315 1.31e-86
histone-lysine N-methyltransferase activity Hs molecular function 315 1.31e-86
histone methyltransferase complex Hs cellular component 315 1.31e-86
histone methyltransferase activity (H3-K4 specific) Hs molecular function 315 1.31e-86
identical protein binding Hs molecular function 169 1.22e-41
protein homodimerization activity Hs molecular function 169 1.22e-41
transcription regulatory region DNA binding Hs molecular function 169 1.22e-41
unmethylated CpG binding Hs molecular function 169 1.22e-41
metal ion binding Hs molecular function 169 1.22e-41
Set1C/COMPASS complex Hs cellular component 315 1.31e-86
lysine-acetylated histone binding Hs molecular function 169 1.22e-41
MLL1 complex Hs cellular component 169 1.22e-41

GO (InterProScan)

6 results

GO Term Analysis Type e-value
nucleic acid binding SUPERFAMILY molecular function 3.66E-15
protein binding SMART molecular function 3.2E-33
histone-lysine N-methyltransferase activity PANTHER molecular function 5.7E-160
histone methyltransferase activity (H3-K4 specific) PANTHER molecular function 7.7E-106
Set1C/COMPASS complex PANTHER cellular component 5.7E-160
histone H3-K4 methylation PANTHER biological process 5.7E-160