Gene Card
Best human hits
EPS15; EPS15L1; ITSN1
Unique Gene ID
Cirobu.g00007223
Gene Model ID
KH2012:KH.C5.348
Location
KhC5:3099609..3114539
Transcript Models and Sequences
KH2012:KH.C5.348.v1.A.SL1-1
KH2012:KH.C5.348.v2.A.ND2-1
KH2012:KH.C5.348.v2.A.SL3-1
cien130804
Plate: VES90_C19
cien206905
Plate: VES102_A10
cieg024n24
Plate: R1CiGC19b21
n/a
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IPR Term | Analysis | Definition |
---|---|---|
EH_dom | ProSiteProfiles | EH domain |
EF_hand_dom | ProSiteProfiles | EF-hand domain |
EH_dom | SMART | EH domain |
EF_hand_dom | SMART | EF-hand domain |
EH_dom | Pfam | EH domain |
UIM_dom | ProSiteProfiles | Ubiquitin interacting motif |
EF-hand-dom_pair | SUPERFAMILY | EF-hand domain pair |
EF_Hand_1_Ca_BS | ProSitePatterns | EF-Hand 1, calcium-binding site |
GO Term | Annotation Origin | Type |
---|---|---|
calcium ion binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
endosome | Orthology | cellular component |
early endosome | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
cell proliferation | Orthology | biological process |
endomembrane system | Orthology | cellular component |
protein transport | Orthology | biological process |
membrane | Orthology | cellular component |
integral component of membrane | Blast | cellular component |
apical plasma membrane | Orthology | cellular component |
lamellipodium | Blast | cellular component |
cell junction | Blast | cellular component |
regulation of cell proliferation | Orthology | biological process |
identical protein binding | Orthology | molecular function |
cell projection | Blast | cellular component |
neuron projection | Blast | cellular component |
intracellular membrane-bounded organelle | Orthology | cellular component |
synapse | Blast | cellular component |
metal ion binding | Orthology | molecular function |
membrane organization | Orthology | biological process |
organelle organization | Orthology | biological process |
membrane part | Orthology | cellular component |
cell surface receptor signaling pathway | Orthology | biological process |
basolateral plasma membrane | Orthology | cellular component |
intracellular part | Orthology | cellular component |
whole membrane | Orthology | cellular component |
plasma membrane part | Orthology | cellular component |
bounding membrane of organelle | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
intracellular organelle part | Orthology | cellular component |
cytoplasmic vesicle | Orthology | cellular component |
intracellular transport | Orthology | biological process |
negative regulation of signal transduction | Orthology | biological process |
cell adhesion molecule binding | Orthology | molecular function |
cell projection membrane | Orthology | cellular component |
enzyme binding | Blast | molecular function |
molecular function regulator | Blast | molecular function |
kinase activity | Blast | molecular function |
enzyme activator activity | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
positive regulation of receptor recycling | Hs | biological process |
calcium ion binding | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
cytoplasm | Hs | cellular component |
endosome | Hs | cellular component |
early endosome | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
clathrin-coated pit | Hs | cellular component |
Golgi to endosome transport | Hs | biological process |
endocytosis | Hs | biological process |
epidermal growth factor receptor signaling pathway | Hs | biological process |
cell proliferation | Hs | biological process |
basal plasma membrane | Hs | cellular component |
protein transport | Hs | biological process |
membrane | Hs | cellular component |
viral process | Hs | biological process |
vesicle organization | Hs | biological process |
aggresome | Hs | cellular component |
apical plasma membrane | Hs | cellular component |
SH3 domain binding | Hs | molecular function |
AP-2 adaptor complex | Hs | cellular component |
clathrin coat of coated pit | Hs | cellular component |
clathrin-coated vesicle | Hs | cellular component |
polyubiquitin modification-dependent protein binding | Hs | molecular function |
early endosome membrane | Hs | cellular component |
endocytic recycling | Hs | biological process |
negative regulation of epidermal growth factor receptor signaling pathway | Hs | biological process |
regulation of cell proliferation | Hs | biological process |
identical protein binding | Hs | molecular function |
intracellular membrane-bounded organelle | Hs | cellular component |
cadherin binding | Hs | molecular function |
viral entry into host cell | Hs | biological process |
metal ion binding | Hs | molecular function |
clathrin coat assembly | Hs | biological process |
ciliary membrane | Hs | cellular component |
membrane organization | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
guanyl-nucleotide exchange factor activity | Hs | molecular function | 124 | 5.93e-29 |
Rho guanyl-nucleotide exchange factor activity | Hs | molecular function | 124 | 5.93e-29 |
calcium ion binding | Hs | molecular function | 484 | 3.72e-158 |
protein binding | Hs | molecular function | 484 | 3.72e-158 |
nucleus | Hs | cellular component | 484 | 3.72e-158 |
cytoplasm | Hs | cellular component | 263 | 3.46e-75 |
endosome | Hs | cellular component | 263 | 3.46e-75 |
early endosome | Hs | cellular component | 263 | 3.46e-75 |
cytosol | Hs | cellular component | 484 | 3.72e-158 |
plasma membrane | Hs | cellular component | 484 | 3.72e-158 |
clathrin-coated pit | Hs | cellular component | 484 | 3.72e-158 |
basal plasma membrane | Hs | cellular component | 263 | 3.46e-75 |
endomembrane system | Hs | cellular component | 124 | 5.93e-29 |
membrane | Hs | cellular component | 484 | 3.72e-158 |
integral component of membrane | Hs | cellular component | 124 | 5.93e-29 |
aggresome | Hs | cellular component | 263 | 3.46e-75 |
apical plasma membrane | Hs | cellular component | 263 | 3.46e-75 |
SH3 domain binding | Hs | molecular function | 263 | 3.46e-75 |
kinase activator activity | Hs | molecular function | 124 | 5.93e-29 |
lamellipodium | Hs | cellular component | 124 | 5.93e-29 |
cell junction | Hs | cellular component | 124 | 5.93e-29 |
AP-2 adaptor complex | Hs | cellular component | 263 | 3.46e-75 |
clathrin coat of coated pit | Hs | cellular component | 484 | 3.72e-158 |
clathrin-coated vesicle | Hs | cellular component | 263 | 3.46e-75 |
endocytic vesicle | Hs | cellular component | 124 | 5.93e-29 |
polyubiquitin modification-dependent protein binding | Hs | molecular function | 263 | 3.46e-75 |
early endosome membrane | Hs | cellular component | 263 | 3.46e-75 |
protein complex scaffold activity | Hs | molecular function | 124 | 5.93e-29 |
identical protein binding | Hs | molecular function | 263 | 3.46e-75 |
cell projection | Hs | cellular component | 124 | 5.93e-29 |
neuron projection | Hs | cellular component | 124 | 5.93e-29 |
intracellular membrane-bounded organelle | Hs | cellular component | 263 | 3.46e-75 |
synapse | Hs | cellular component | 124 | 5.93e-29 |
cadherin binding | Hs | molecular function | 484 | 3.72e-158 |
metal ion binding | Hs | molecular function | 484 | 3.72e-158 |
ciliary membrane | Hs | cellular component | 263 | 3.46e-75 |
proline-rich region binding | Hs | molecular function | 124 | 5.93e-29 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
calcium ion binding | SMART | molecular function | 0.029 |
protein binding | SMART | molecular function | 7.4E-43 |