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Gene Card

Best human hits

TIMP2; TIMP3; TIMP4

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00007481

Gene Model ID

KH2012:KH.C5.581

Location

KhC5:3365326..3369829

Transcript Models and Sequences

  KH2012:KH.C5.581.v1.A.ND2-1
KH2012:KH.C5.581.v1.A.SL1-1

External Database Gene Card

External database links

3 results

Database Gene ID
ENSEMBL ENSCING00000012173
ENSEMBL ENSCING00000022769
NCBI Reference Sequence XM_002131387.4
Collections

Gateway full ORF

2 results

cima881775

Plate: VES68_E24

cien137084

Plate: VES91_F18

Gene collection 1 (N. Satoh)

2 results

ciad014i08

Plate: R1CiGC02d21

ciad079o21

Plate: R1CiGC07l04

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

6 results

IPR Term Analysis Definition
TIMP PANTHER Protease inhibitor I35 (TIMP)
TIMP_CS ProSitePatterns Tissue inhibitor of metalloproteinase, conserved site
TIMP SMART Protease inhibitor I35 (TIMP)
TIMP-like_OB-fold SUPERFAMILY Tissue inhibitor of metalloproteinases-like, OB-fold
TIMP Pfam Protease inhibitor I35 (TIMP)
TIMP_C Gene3D Proteinase inhibitor I35b (TIMP), C-terminal

GOSlim

25 results

GO Term Annotation Origin Type
integrin binding Blast molecular function
protein binding Blast molecular function
extracellular region Blast cellular component
extracellular space Blast cellular component
nucleus Blast cellular component
zinc ion binding Blast molecular function
cell surface Blast cellular component
neuron projection Blast cellular component
neuronal cell body Blast cellular component
metal ion binding Blast molecular function
extracellular exosome Blast cellular component
enzyme binding Blast molecular function
enzyme regulator activity Blast molecular function
extracellular region part Blast cellular component
metalloendopeptidase activity Blast molecular function
cytoplasmic part Blast cellular component
organelle part Blast cellular component
intracellular non-membrane-bounded organelle Blast cellular component
peptidase activity Blast molecular function
cell projection part Blast cellular component
axon Blast cellular component
intracellular organelle part Blast cellular component
cytoplasmic vesicle Blast cellular component
endomembrane system Blast cellular component
intracellular organelle lumen Blast cellular component

GO (Orthology)

No result

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type

GO (Blast)

24 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
protease binding Hs molecular function 79.7 6.50e-17
enzyme inhibitor activity Hs molecular function 79.7 6.50e-17
integrin binding Hs molecular function 79.7 6.50e-17
protein binding Hs molecular function 79.7 6.50e-17
extracellular region Hs cellular component 79.7 6.50e-17
proteinaceous extracellular matrix Hs cellular component 79.7 6.50e-17
basement membrane Hs cellular component 68.9 2.59e-13
extracellular space Hs cellular component 79.7 6.50e-17
nucleus Hs cellular component 68.9 2.59e-13
metalloendopeptidase inhibitor activity Hs molecular function 79.7 6.50e-17
zinc ion binding Hs molecular function 79.7 6.50e-17
cell surface Hs cellular component 79.7 6.50e-17
sarcomere Hs cellular component 65.9 3.74e-12
peptidase inhibitor activity Hs molecular function 79.7 6.50e-17
growth cone Hs cellular component 79.7 6.50e-17
extracellular matrix Hs cellular component 79.7 6.50e-17
platelet dense granule lumen Hs cellular component 68.9 2.59e-13
specific granule lumen Hs cellular component 79.7 6.50e-17
neuron projection Hs cellular component 79.7 6.50e-17
neuronal cell body Hs cellular component 79.7 6.50e-17
metal ion binding Hs molecular function 79.7 6.50e-17
extracellular exosome Hs cellular component 79.7 6.50e-17
tertiary granule lumen Hs cellular component 79.7 6.50e-17
ficolin-1-rich granule lumen Hs cellular component 79.7 6.50e-17

GO (InterProScan)

1 result

GO Term Analysis Type e-value
metalloendopeptidase inhibitor activity PANTHER molecular function 1.3E-58

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