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Gene Card

Best human hits

BTRC; FBXW11; FBXW7

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00007587

Gene Model ID

KH2012:KH.C5.76

Location

KhC5:2913269..2927252

Transcript Models and Sequences

  KH2012:KH.C5.76.v1.A.nonSL3-1
KH2012:KH.C5.76.v1.A.SL1-1
KH2012:KH.C5.76.v1.A.SL2-1
KH2012:KH.C5.76.v2.A.nonSL3-1
KH2012:KH.C5.76.v2.A.SL1-1
KH2012:KH.C5.76.v2.A.SL2-1

External Database Gene Card

External database links

3 results

Database Gene ID
ENSEMBL ENSCING00000009295
NCBI Reference Sequence NM_001032454.1
NCBI Reference Sequence XM_009860216.2
Collections

Gateway full ORF

2 results

cien98222

Plate: VES85_P16

cima883818

Plate: VES69_K09

Gene collection 1 (N. Satoh)

2 results

cieg001c06

Plate: R1CiGC15o08

cign076g10

Plate: R1CiGC43e05

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

14 results

IPR Term Analysis Definition
WD40_repeat ProSiteProfiles WD40 repeat
F-box_dom Pfam F-box domain
WD40_repeat_CS ProSitePatterns WD40 repeat, conserved site
Beta-TrCP_D Pfam D domain of beta-TrCP
WD40/YVTN_repeat-like_dom_sf Gene3D WD40/YVTN repeat-like-containing domain superfamily
F-box_dom SMART F-box domain
WD40_repeat Pfam WD40 repeat
Beta-TrCP_D SMART D domain of beta-TrCP
F-box-like_dom_sf SUPERFAMILY F-box-like domain superfamily
WD40_repeat_dom_sf SUPERFAMILY WD40-repeat-containing domain superfamily
F-box_dom ProSiteProfiles F-box domain
WD40_repeat_dom ProSiteProfiles WD40-repeat-containing domain
G-protein_beta_WD-40_rep PRINTS G-protein beta WD-40 repeat
WD40_repeat SMART WD40 repeat

GOSlim

40 results

GO Term Annotation Origin Type
G2/M transition of mitotic cell cycle Orthology biological process
protein polyubiquitination Orthology biological process
ubiquitin-protein transferase activity Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
nucleolus Blast cellular component
cytoplasm Orthology cellular component
centrosome Orthology cellular component
cytosol Orthology cellular component
protein dephosphorylation Orthology biological process
cell cycle Orthology biological process
signal transduction Orthology biological process
protein ubiquitination Orthology biological process
ligase activity Orthology molecular function
ubiquitin protein ligase binding Blast molecular function
identical protein binding Blast molecular function
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription, DNA-templated Orthology biological process
protein dimerization activity Orthology molecular function
regulation of canonical Wnt signaling pathway Orthology biological process
intracellular part Orthology cellular component
macromolecular complex Orthology cellular component
proteolysis Orthology biological process
cell surface receptor signaling pathway Orthology biological process
cell-cell signaling Orthology biological process
protein metabolic process Orthology biological process
transcription factor activity, sequence-specific DNA binding Orthology molecular function
intracellular signal transduction Orthology biological process
immune response Orthology biological process
regulation of signal transduction Orthology biological process
regulation of molecular function Orthology biological process
cellular protein modification process Orthology biological process
negative regulation of signal transduction Orthology biological process
cellular response to stress Orthology biological process
protein phosphorylation Orthology biological process
regulation of cellular metabolic process Orthology biological process
cytokine-mediated signaling pathway Orthology biological process
cellular response to organic substance Orthology biological process
enzyme regulator activity Blast molecular function

GO (Orthology)

46 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
G2/M transition of mitotic cell cycle Hs biological process
ubiquitin ligase complex Hs cellular component
protein polyubiquitination Hs biological process
ubiquitin-protein transferase activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
centrosome Hs cellular component
cytosol Hs cellular component
protein dephosphorylation Hs biological process
ubiquitin-dependent protein catabolic process Hs biological process
cell cycle Hs biological process
signal transduction Hs biological process
beta-catenin binding Hs molecular function
viral process Hs biological process
Wnt signaling pathway Hs biological process
protein ubiquitination Hs biological process
ligase activity Hs molecular function
SCF ubiquitin ligase complex Hs cellular component
protein catabolic process Hs biological process
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Hs biological process
protein destabilization Hs biological process
NIK/NF-kappaB signaling Hs biological process
Fc-epsilon receptor signaling pathway Hs biological process
regulation of circadian rhythm Hs biological process
positive regulation of circadian rhythm Hs biological process
regulation of I-kappaB kinase/NF-kappaB signaling Hs biological process
proteasome-mediated ubiquitin-dependent protein catabolic process Hs biological process
negative regulation of sequence-specific DNA binding transcription factor activity Hs biological process
post-translational protein modification Hs biological process
protein phosphorylated amino acid binding Hs molecular function
positive regulation of proteolysis Hs biological process
negative regulation of smoothened signaling pathway Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
protein dimerization activity Hs molecular function
rhythmic process Hs biological process
T cell receptor signaling pathway Hs biological process
stress-activated MAPK cascade Hs biological process
regulation of cell cycle Hs biological process
regulation of canonical Wnt signaling pathway Hs biological process
regulation of proteasomal protein catabolic process Hs biological process
ubiquitin protein ligase activity Hs molecular function
interleukin-1-mediated signaling pathway Hs biological process
cellular response to organic cyclic compound Hs biological process

GO (Blast)

22 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
ubiquitin ligase complex Hs cellular component 825 0.0
ubiquitin-protein transferase activity Hs molecular function 835 0.0
protein binding Hs molecular function 835 0.0
nucleus Hs cellular component 835 0.0
nucleoplasm Hs cellular component 835 0.0
nucleolus Hs cellular component 228 1.74e-65
cytoplasm Hs cellular component 835 0.0
centrosome Hs cellular component 825 0.0
cytosol Hs cellular component 835 0.0
beta-catenin binding Hs molecular function 835 0.0
ligase activity Hs molecular function 835 0.0
SCF ubiquitin ligase complex Hs cellular component 835 0.0
cyclin binding Hs molecular function 228 1.74e-65
protein binding, bridging Hs molecular function 228 1.74e-65
ubiquitin protein ligase binding Hs molecular function 228 1.74e-65
identical protein binding Hs molecular function 228 1.74e-65
protein phosphorylated amino acid binding Hs molecular function 835 0.0
protein dimerization activity Hs molecular function 835 0.0
phosphothreonine residue binding Hs molecular function 228 1.74e-65
ubiquitin protein ligase activity Hs molecular function 835 0.0
ubiquitin-protein transferase activator activity Hs molecular function 228 1.74e-65
Parkin-FBXW7-Cul1 ubiquitin ligase complex Hs cellular component 228 1.74e-65

GO (InterProScan)

2 results

GO Term Analysis Type e-value
protein binding Gene3D molecular function 8.7E-106
protein dimerization activity SMART molecular function 1.4E-26

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