Database	Gene ID
NCBI Reference Sequence	XM_002121978.3
NCBI Reference Sequence	XM_018812204.1
NCBI Reference Sequence	XM_018812205.1
NCBI Reference Sequence	XM_018812206.1
NCBI Reference Sequence	XM_018812207.1

IPR Term	Analysis	Definition
Endo/exonu/phosph_ase_sf	Gene3D	Endonuclease/exonuclease/phosphatase superfamily
Endo/exonu/phosph_ase_sf	SUPERFAMILY	Endonuclease/exonuclease/phosphatase superfamily
RhoGAP_dom	Pfam	Rho GTPase-activating protein domain
Ig-like_fold	Gene3D	Immunoglobulin-like fold
RhoGAP_dom	SMART	Rho GTPase-activating protein domain
IPPc	SMART	Inositol polyphosphate-related phosphatase
Rho_GTPase_activation_prot	SUPERFAMILY	Rho GTPase activation protein
Endo/exonuclease/phosphatase	Pfam	Endonuclease/exonuclease/phosphatase
OCRL1/INPP5B_INPP5c	CDD	OCRL1/INPP5B, INPP5c domain
Rho_GTPase_activation_prot	Gene3D	Rho GTPase activation protein
RhoGAP_dom	ProSiteProfiles	Rho GTPase-activating protein domain

GO Term	Annotation Origin	Type
nucleic acid binding	Blast	molecular function
RNA binding	Blast	molecular function
GTPase activator activity	Orthology	molecular function
protein binding	Orthology	molecular function
cell	Blast	cellular component
nucleus	Orthology	cellular component
cytoplasm	Orthology	cellular component
endosome	Orthology	cellular component
early endosome	Orthology	cellular component
Golgi apparatus	Orthology	cellular component
cytosol	Orthology	cellular component
microtubule	Blast	cellular component
plasma membrane	Orthology	cellular component
signal transduction	Orthology	biological process
spermatogenesis	Orthology	biological process
protein C-terminus binding	Blast	molecular function
membrane	Orthology	cellular component
integral component of membrane	Orthology	cellular component
hydrolase activity	Orthology	molecular function
cell projection organization	Orthology	biological process
cytoplasmic vesicle	Orthology	cellular component
cell projection	Orthology	cellular component
neuron projection	Orthology	cellular component
regulation of GTPase activity	Orthology	biological process
positive regulation of GTPase activity	Orthology	biological process
synapse	Blast	cellular component
metal ion binding	Orthology	molecular function
perinuclear region of cytoplasm	Blast	cellular component
membrane organization	Orthology	biological process
extracellular exosome	Orthology	cellular component
synaptic membrane	Blast	cellular component
organelle part	Orthology	cellular component
cell projection part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
dephosphorylation	Orthology	biological process
cytoplasmic part	Orthology	cellular component
intracellular membrane-bounded organelle	Orthology	cellular component
Golgi apparatus part	Orthology	cellular component
membrane part	Orthology	cellular component
endomembrane system	Orthology	cellular component
organelle	Orthology	cellular component
plasma membrane region	Orthology	cellular component
organic substance metabolic process	Orthology	biological process
cellular biosynthetic process	Orthology	biological process
phosphate-containing compound metabolic process	Orthology	biological process
reproductive process	Orthology	biological process
cell motility	Orthology	biological process
intracellular organelle part	Orthology	cellular component
whole membrane	Orthology	cellular component
bounding membrane of organelle	Orthology	cellular component
enzyme binding	Orthology	molecular function
small GTPase mediated signal transduction	Orthology	biological process
regulation of signal transduction	Orthology	biological process
regulation of gene expression	Orthology	biological process
proteolysis	Orthology	biological process
vesicle	Blast	cellular component
organelle membrane	Blast	cellular component
plasma membrane part	Blast	cellular component
axon	Blast	cellular component
synapse part	Blast	cellular component
neuron part	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
photoreceptor outer segment	Hs	cellular component
phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	Hs	molecular function
GTPase activator activity	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
cytoplasm	Hs	cellular component
endosome	Hs	cellular component
early endosome	Hs	cellular component
endoplasmic reticulum-Golgi intermediate compartment	Hs	cellular component
Golgi apparatus	Hs	cellular component
Golgi stack	Hs	cellular component
Golgi-associated vesicle	Hs	cellular component
trans-Golgi network	Hs	cellular component
cytosol	Hs	cellular component
plasma membrane	Hs	cellular component
clathrin-coated pit	Hs	cellular component
cilium	Hs	cellular component
lipid metabolic process	Hs	biological process
phosphatidylinositol biosynthetic process	Hs	biological process
signal transduction	Hs	biological process
spermatogenesis	Hs	biological process
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
hydrolase activity	Hs	molecular function
cell projection organization	Hs	biological process
clathrin-coated vesicle	Hs	cellular component
flagellated sperm motility	Hs	biological process
phagocytic vesicle membrane	Hs	cellular component
cytoplasmic vesicle	Hs	cellular component
early endosome membrane	Hs	cellular component
phosphatidylinositol phosphate 4-phosphatase activity	Hs	molecular function
phosphatidylinositol-3-phosphate biosynthetic process	Hs	biological process
cell projection	Hs	cellular component
regulation of GTPase activity	Hs	biological process
positive regulation of GTPase activity	Hs	biological process
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	Hs	molecular function
phosphatidylinositol dephosphorylation	Hs	biological process
metal ion binding	Hs	molecular function
Rac GTPase binding	Hs	molecular function
regulation of small GTPase mediated signal transduction	Hs	biological process
inositol-1,4,5-trisphosphate 5-phosphatase activity	Hs	molecular function
inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	Hs	molecular function
inositol phosphate phosphatase activity	Hs	molecular function
cilium assembly	Hs	biological process
membrane organization	Hs	biological process
extracellular exosome	Hs	cellular component
regulation of protein processing	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
photoreceptor outer segment	Hs	cellular component	674	0.0
nucleic acid binding	Hs	molecular function	227	1.83e-61
RNA binding	Hs	molecular function	227	1.83e-61
phosphatidylinositol-3-phosphatase activity	Hs	molecular function	227	1.83e-61
phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	Hs	molecular function	674	0.0
GTPase activator activity	Hs	molecular function	674	0.0
protein binding	Hs	molecular function	674	0.0
cell	Hs	cellular component	227	1.83e-61
nucleus	Hs	cellular component	674	0.0
cytoplasm	Hs	cellular component	674	0.0
endosome	Hs	cellular component	674	0.0
early endosome	Hs	cellular component	674	0.0
endoplasmic reticulum-Golgi intermediate compartment	Hs	cellular component	671	0.0
Golgi apparatus	Hs	cellular component	674	0.0
Golgi stack	Hs	cellular component	674	0.0
Golgi-associated vesicle	Hs	cellular component	674	0.0
trans-Golgi network	Hs	cellular component	674	0.0
cytosol	Hs	cellular component	674	0.0
microtubule	Hs	cellular component	227	1.83e-61
plasma membrane	Hs	cellular component	674	0.0
clathrin-coated pit	Hs	cellular component	674	0.0
cilium	Hs	cellular component	674	0.0
protein C-terminus binding	Hs	molecular function	227	1.83e-61
vesicle membrane	Hs	cellular component	227	1.83e-61
membrane	Hs	cellular component	674	0.0
integral component of membrane	Hs	cellular component	671	0.0
hydrolase activity	Hs	molecular function	674	0.0
SH3 domain binding	Hs	molecular function	227	1.83e-61
membrane coat	Hs	cellular component	227	1.83e-61
clathrin coat of coated pit	Hs	cellular component	227	1.83e-61
clathrin-coated vesicle	Hs	cellular component	674	0.0
phagocytic vesicle membrane	Hs	cellular component	674	0.0
cytoplasmic vesicle	Hs	cellular component	674	0.0
early endosome membrane	Hs	cellular component	674	0.0
phosphatidylinositol phosphate 5-phosphatase activity	Hs	molecular function	227	1.83e-61
phosphatidylinositol phosphate 4-phosphatase activity	Hs	molecular function	674	0.0
phosphoric ester hydrolase activity	Hs	molecular function	227	1.83e-61
cell projection	Hs	cellular component	674	0.0
neuron projection	Hs	cellular component	227	1.83e-61
terminal bouton	Hs	cellular component	227	1.83e-61
phosphatidylinositol-4-phosphate phosphatase activity	Hs	molecular function	227	1.83e-61
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	Hs	molecular function	674	0.0
synapse	Hs	cellular component	227	1.83e-61
metal ion binding	Hs	molecular function	671	0.0
Rac GTPase binding	Hs	molecular function	674	0.0
perinuclear region of cytoplasm	Hs	cellular component	227	1.83e-61
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	Hs	molecular function	227	1.83e-61
inositol-1,4,5-trisphosphate 5-phosphatase activity	Hs	molecular function	674	0.0
inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	Hs	molecular function	674	0.0
inositol phosphate phosphatase activity	Hs	molecular function	674	0.0
extracellular exosome	Hs	cellular component	674	0.0
synaptic membrane	Hs	cellular component	227	1.83e-61
presynapse	Hs	cellular component	227	1.83e-61

GO Term	Analysis	Type	e-value
signal transduction	Gene3D	biological process	6.7E-45
phosphatidylinositol dephosphorylation	SMART	biological process	1.5E-106
inositol phosphate phosphatase activity	CDD	molecular function	0.0