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Gene Card

Best human hits

MYH4; ROCK1; ROCK2

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00008160

Gene Model ID

KH2012:KH.C7.324

Location

KhC7:5210777..5243787

Transcript Models and Sequences

  KH2012:KH.C7.324.v1.C.SL2-1
KH2012:KH.C7.324.v1.C.SL4-1
KH2012:KH.C7.324.v2.C.SL2-4
KH2012:KH.C7.324.v2.C.SL4-4
KH2012:KH.C7.324.v3.C.ND1-1
KH2012:KH.C7.324.v4.C.SL2-2
KH2012:KH.C7.324.v4.C.SL4-2
KH2012:KH.C7.324.v5.C.ND3-3

External Database Gene Card

External database links

3 results

Database Gene ID
ENSEMBL ENSCING00000003143
NCBI Reference Sequence XM_018812427.1
NCBI Reference Sequence XM_018812428.1
Collections

Gateway full ORF

2 results

cien163108

Plate: VES95_L12

cien212666

Plate: VES103_J06

Gene collection 1 (N. Satoh)

2 results

cilv002k08

Plate: R1CiGC25e01

citb036p05

Plate: R1CiGC32i20

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

17 results

IPR Term Analysis Definition
PH_domain SMART Pleckstrin homology domain
PE/DAG-bd CDD Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
ROCK2 PANTHER Rho-associated protein kinase 2
PH_domain ProSiteProfiles Pleckstrin homology domain
PE/DAG-bd SMART Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
PH-like_dom_sf Gene3D PH-like domain superfamily
Rho-bd_dom Pfam Rho binding domain
PE/DAG-bd ProSiteProfiles Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
Prot_kinase_dom Pfam Protein kinase domain
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site
Ser/Thr_kinase_AS ProSitePatterns Serine/threonine-protein kinase, active site
LET-502 PANTHER Rho-associated protein kinase LET-502
AGC-kinase_C ProSiteProfiles AGC-kinase, C-terminal
AGC-kinase_C SMART AGC-kinase, C-terminal
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Prot_kinase_dom SMART Protein kinase domain

GOSlim

48 results

GO Term Annotation Origin Type
Golgi membrane Blast cellular component
nucleotide binding Blast molecular function
RNA binding Blast molecular function
motor activity Blast molecular function
microtubule motor activity Blast molecular function
actin binding Blast molecular function
protein kinase activity Blast molecular function
protein serine/threonine kinase activity Blast molecular function
structural molecule activity Blast molecular function
protein binding Blast molecular function
calmodulin binding Blast molecular function
ATP binding Blast molecular function
extracellular region Blast cellular component
intracellular Blast cellular component
nucleus Blast cellular component
cytoplasm Blast cellular component
Golgi apparatus Blast cellular component
centrosome Blast cellular component
microtubule organizing center Blast cellular component
cytosol Blast cellular component
cytoskeleton Blast cellular component
plasma membrane Blast cellular component
protein phosphorylation InterProScan biological process
microtubule binding Blast molecular function
membrane Blast cellular component
kinase activity Blast molecular function
transferase activity Blast molecular function
lamellipodium Blast cellular component
intracellular signal transduction InterProScan biological process
cell projection Blast cellular component
metal ion binding Blast molecular function
actin filament binding Blast molecular function
plasma membrane region Blast cellular component
cell leading edge Blast cellular component
cytoplasmic part Blast cellular component
cytoskeletal part Blast cellular component
macromolecular complex Blast cellular component
nucleoside-triphosphatase activity Blast molecular function
enzyme binding Blast molecular function
intracellular non-membrane-bounded organelle Blast cellular component
organelle part Blast cellular component
intracellular organelle part Blast cellular component
cytoplasmic vesicle Blast cellular component
endomembrane system Blast cellular component
intracellular organelle lumen Blast cellular component
small GTPase mediated signal transduction InterProScan biological process
organelle organization InterProScan biological process
microtubule-based process InterProScan biological process

GO (Orthology)

No result

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type

GO (Blast)

47 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
Golgi membrane Hs cellular component 466 1.80e-148
microfilament motor activity Hs molecular function 41.2 0.003
nucleotide binding Hs molecular function 511 2.01e-165
ruffle Hs cellular component 466 1.80e-148
RNA binding Hs molecular function 511 2.01e-165
double-stranded RNA binding Hs molecular function 41.2 0.003
motor activity Hs molecular function 41.2 0.003
microtubule motor activity Hs molecular function 41.2 0.003
actin binding Hs molecular function 41.2 0.003
protein kinase activity Hs molecular function 511 2.01e-165
protein serine/threonine kinase activity Hs molecular function 511 2.01e-165
structural molecule activity Hs molecular function 511 2.01e-165
protein binding Hs molecular function 511 2.01e-165
calmodulin binding Hs molecular function 41.2 0.003
ATP binding Hs molecular function 511 2.01e-165
extracellular region Hs cellular component 466 1.80e-148
intracellular Hs cellular component 511 2.01e-165
nucleus Hs cellular component 511 2.01e-165
cytoplasm Hs cellular component 511 2.01e-165
Golgi apparatus Hs cellular component 466 1.80e-148
centrosome Hs cellular component 511 2.01e-165
centriole Hs cellular component 466 1.80e-148
microtubule organizing center Hs cellular component 511 2.01e-165
cytosol Hs cellular component 511 2.01e-165
cytoskeleton Hs cellular component 511 2.01e-165
muscle myosin complex Hs cellular component 41.2 0.003
plasma membrane Hs cellular component 511 2.01e-165
microtubule binding Hs molecular function 41.2 0.003
membrane Hs cellular component 511 2.01e-165
kinase activity Hs molecular function 511 2.01e-165
myosin complex Hs cellular component 41.2 0.003
transferase activity Hs molecular function 511 2.01e-165
ATPase activity Hs molecular function 41.2 0.003
Rho GTPase binding Hs molecular function 511 2.01e-165
GTP-Rho binding Hs molecular function 511 2.01e-165
myofibril Hs cellular component 41.2 0.003
sarcomere Hs cellular component 41.2 0.003
lamellipodium Hs cellular component 466 1.80e-148
bleb Hs cellular component 466 1.80e-148
myosin filament Hs cellular component 41.2 0.003
secretory granule lumen Hs cellular component 466 1.80e-148
cytoplasmic ribonucleoprotein granule Hs cellular component 511 2.01e-165
cell projection Hs cellular component 466 1.80e-148
metal ion binding Hs molecular function 511 2.01e-165
actin filament binding Hs molecular function 41.2 0.003
Rho-dependent protein serine/threonine kinase activity Hs molecular function 511 2.01e-165
amyloid-beta complex Hs cellular component 466 1.80e-148

GO (InterProScan)

10 results

GO Term Analysis Type e-value
protein kinase activity SMART molecular function 8.0E-95
protein serine/threonine kinase activity PANTHER molecular function 0.0
ATP binding SMART molecular function 8.0E-95
protein phosphorylation SMART biological process 8.0E-95
smooth muscle contraction PANTHER biological process 1.5E-185
Rho protein signal transduction PANTHER biological process 1.5E-185
positive regulation of centrosome duplication PANTHER biological process 1.5E-185
Rho GTPase binding Pfam molecular function 1.0E-21
regulation of actin cytoskeleton organization PANTHER biological process 1.5E-185
intracellular signal transduction CDD biological process 7.42447E-10

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